|
|
reduced_flavodoxin + N2 + ATP + H2O <=> flavin + NH3 + H2 + ADP + phosphate + H+
|
1.19.6.1
nitrogenase (flavodoxin)
|
–
|
MK
|
|
BRENDA:
BR40513
KEGG:
R05186
MetaCyc:
NITROGENASE-FLAVODOXIN-RXN
|
|
|
|
L-arginine + reduced_flavodoxin + O2 <=> L-citrulline + NO + flavin + H2O + H+
|
1.14.14.47
nitric-oxide synthase (flavodoxin)
|
–
|
K
|
|
BRENDA:
BR40515
KEGG:
R11711
MetaCyc:
RXN-13568
|
|
|
|
reduced_flavodoxin + NAD+ <=> flavin + NADH + H+
|
1.5.1.36
flavin reductase (NADH)
|
–
|
|
|
BRENDA:
BR49640
KEGG:
R09662
MetaCyc:
RXN-12446
|
|
|
|
Nomega-hydroxy-L-arginine + reduced_flavodoxin + O2 <=> L-citrulline + NO + flavin + H2O + H+
|
1.14.14.47
nitric-oxide synthase (flavodoxin)
|
–
|
MK
|
|
BRENDA:
BR50159
KEGG:
R11713
MetaCyc:
RXN-13567
|
|
|
|
a_7-oxoheptanoyl-[acyl-carrier_protein] + flavin + H2O <=> pimeloyl-[acyl-carrier_protein] + reduced_flavodoxin + H+
|
1.14.14.46
pimeloyl-[acyl-carrier protein] synthase
|
–
|
|
|
BRENDA:
BR50377
MetaCyc:
RXN-13837
|
|
|
|
(E)-4-hydroxy-3-methylbut-2-en-1-yl_diphosphate + flavin + H2O + H+ <=> 2-C-methyl-D-erythritol_2,4-cyclodiphosphate + reduced_flavodoxin
|
1.17.7.3
(E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase (flavodoxin)
|
–
|
MK
|
|
BRENDA:
BR51177
KEGG:
R10859
MetaCyc:
RXN-15878
|
|
|
|
reduced_flavodoxin + NADP+ <=> flavin + NADPH + H+
|
1.19.1.1
flavodoxin---NADP+ reductase
1.6.2.4
NADPH---hemoprotein reductase
|
–
–
|
|
|
BRENDA:
BR51843
KEGG:
R08551;
R11485
MetaCyc:
FLAVONADPREDUCT-RXN
|
|
|
|
S-adenosyl-L-methionine + heme + reduced_flavodoxin <=> anaerobilin + L-methionine + 5''-deoxyadenosine + S-adenosyl-L-homocysteine + Fe2+ + flavin
|
2.1.1.342
anaerobilin synthase
|
–
|
M
|
|
BRENDA:
BR52055
KEGG:
R11700
MetaCyc:
RXN-18337
|
|
|
|
L-arginine + reduced_flavodoxin + O2 <=> Nomega-hydroxy-L-arginine + flavin + H2O
|
1.14.14.47
nitric-oxide synthase (flavodoxin)
|
–
|
MK
|
|
BRENDA:
BR52113
KEGG:
R11712
MetaCyc:
RXN-13566
|
|
|
|
S-adenosyl-L-methionine + menaquinone + reduced_flavodoxin <=> an_8-methylmenaquinone + S-adenosyl-L-homocysteine + L-methionine + 5''-deoxyadenosine + flavin + H+
|
2.1.1.350
menaquinone C8-methyltransferase
|
–
|
M
|
|
BRENDA:
BR52531
KEGG:
R12238
MetaCyc:
RXN-18515
|
|
|
|
S-adenosyl-L-methionine + 2-demethylmenaquinone + reduced_flavodoxin <=> a_2-demethyl-8-methylmenaquinone + S-adenosyl-L-homocysteine + L-methionine + 5''-deoxyadenosine + flavin + H+
|
2.1.1.350
menaquinone C8-methyltransferase
|
–
|
|
|
BRENDA:
BR52532
KEGG:
R12239
MetaCyc:
RXN-18518
|
|
|
|
reduced_flavodoxin + an_inactive_(R)-2-hydroxyacyl-CoA_dehydratase + ATP + H2O <=> reduced_flavodoxin + an_active_(R)-2-hydroxyacyl-CoA_dehydratase + ADP + phosphate + H+
|
5.6.1.9
(R)-2-hydroxyacyl-CoA dehydratase activating ATPase
|
–
|
|
|
BRENDA:
BR52952
MetaCyc:
RXN-19894
|
|
|
|
trimethylamine + H2O + oxidized_electron_transfer_flavoprotein + H+ <=> Dimethylamine + formaldehyde + reduced_flavodoxin
|
1.5.8.2
trimethylamine dehydrogenase
|
–
|
|
|
BRENDA:
BS374767
MetaCyc:
1.5.8.2-RXN
|
|
|
|
S-adenosyl-L-methionine + menaquinone-6 + reduced_flavodoxin <=> 8-methylmenaquinone-6 + S-adenosyl-L-homocysteine + L-methionine + 5''-deoxyadenosine + flavin + H+
|
2.1.1.350
menaquinone C8-methyltransferase
|
–
|
|
|
BRENDA:
BS444604
MetaCyc:
RXN-18516
|
|
|
|
2-methylbutanoyl-CoA + flavin <=> tigloyl-CoA + reduced_flavodoxin + H+
|
1.3.8.5
2-methyl-branched-chain-enoyl-CoA reductase
1.3.99.12
2-methylacyl-CoA dehydrogenase
|
–
–
|
|
|
BRENDA:
BR1200
KEGG:
R03169
|
|
|
|
cholesterol + reduced_flavodoxin + O2 <=> 7alpha-hydroxycholesterol + flavin + H2O
|
1.14.14.23
cholesterol 7alpha-monooxygenase
|
–
|
BK
|
|
BRENDA:
BR29138
KEGG:
R01463
|
|
|
|
(S)-N-methylcanadine + reduced_flavodoxin + O2 <=> Allocryptopine + flavin + H2O
|
1.14.14.97
methyltetrahydroprotoberberine 14-monooxygenase
|
–
|
K
|
|
BRENDA:
BR29140
KEGG:
R03842
|
|
|
|
formononetin + reduced_flavodoxin + O2 <=> Calycosin + flavin + H2O
|
1.14.14.88
isoflavone 3'-hydroxylase
|
–
|
K
|
|
BRENDA:
BR29141
KEGG:
R03006
|
|
|
|
formononetin + reduced_flavodoxin + O2 <=> 2''-hydroxyformononetin + flavin + H2O
|
1.14.14.89
4'-methoxyisoflavone 2'-hydroxylase
1.14.14.90
isoflavone 2'-hydroxylase
|
–
–
|
K
|
|
BRENDA:
BR29142
KEGG:
R06560
|
|
|
|
Quinine + reduced_flavodoxin + O2 <=> 3-hydroxyquinine + flavin + H2O
|
1.14.14.55
quinine 3-monooxygenase
|
–
|
|
|
BRENDA:
BR29143
KEGG:
R05727
|
|
|
|
p-hydroxyphenylacetaldoxime + reduced_flavodoxin + O2 <=> (S)-4-hydroxymandelonitrile + flavin + 2 H2O
|
1.14.14.37
4-hydroxyphenylacetaldehyde oxime monooxygenase
|
–
|
K
|
|
BRENDA:
BR29144
KEGG:
R05728
|
|
|
|
a_14alpha-methylsteroid + 3 reduced_flavodoxin + 3 O2 <=> a_DELTA14-steroid + formate + 3 flavin + 4 H2O
|
1.14.14.154
sterol 14alpha-demethylase
|
–
|
|
|
BRENDA:
BR29146
KEGG:
R12118
|
|
|
|
(S)-N-methylcoclaurine + reduced_flavodoxin + O2 <=> (S)-3''-hydroxy-N-methylcoclaurine + flavin + H2O
|
1.14.14.102
N-methylcoclaurine 3'-monooxygenase
|
–
|
K
|
|
BRENDA:
BR29147
KEGG:
R05732
|
|
|
|
trans-cinnamate + reduced_flavodoxin + O2 <=> p-coumaric_acid + flavin + H2O
|
1.14.14.91
trans-cinnamate 4-monooxygenase
|
–
|
BK
|
|
BRENDA:
BR33713
KEGG:
R02253
|
|
|
|
17alpha-hydroxyprogesterone + reduced_flavodoxin + O2 <=> 4-androstene-3,17-dione + acetate + flavin + H2O
|
1.14.14.32
17alpha-hydroxyprogesterone deacetylase
|
–
|
BK
|
|
BRENDA:
BR362
KEGG:
R08518
|
|
|
|
demethylmedicarpin + reduced_flavodoxin + O2 <=> (6aS,11aS)-3,6a,9-trihydroxypterocarpan + flavin + H2O
|
1.14.14.93
3,9-dihydroxypterocarpan 6a-monooxygenase
|
–
|
K
|
|
BRENDA:
BR36760
KEGG:
R03452
|
|
|
|
leukotriene_B4 + reduced_flavodoxin + O2 <=> 20-hydroxy-leukotriene_B4 + flavin + H2O
|
1.14.14.78
phylloquinone omega-hydroxylase
1.14.14.94
leukotriene-B4 20-monooxygenase
|
–
–
|
K
|
|
BRENDA:
BR36761
KEGG:
R03866
|
|
|
|
L-tyrosine + O2 + reduced_flavodoxin <=> N-hydroxy-L-tyrosine + flavin + H2O
|
1.14.14.36
tyrosine N-monooxygenase
|
–
|
K
|
|
BRENDA:
BR36762
KEGG:
R00730
|
|
|
|
(-)-limonene + reduced_flavodoxin + O2 <=> (-)-trans-isopiperitenol + flavin + H2O
|
1.14.14.99
(S)-limonene 3-monooxygenase
|
–
|
K
|
|
BRENDA:
BR36763
KEGG:
R02469
|
|
|
|
(-)-limonene + reduced_flavodoxin + O2 <=> (-)-trans-carveol + flavin + H2O
|
1.14.14.51
(S)-limonene 6-monooxygenase
|
–
|
K
|
|
BRENDA:
BR36764
KEGG:
R02468
|
|
|
|
(-)-limonene + reduced_flavodoxin + O2 <=> (S)-perillyl_alcohol + flavin + H2O
|
1.14.14.52
(S)-limonene 7-monooxygenase
|
–
|
K
|
|
BRENDA:
BR36765
KEGG:
R02470
|
|
|
|
A + reduced_flavodoxin + O2 <=> rhodopsin + flavin + H2O
|
1.14.13.231
tetracycline 11a-monooxygenase
1.14.14.1
unspecific monooxygenase
|
–
–
|
|
|
BRENDA:
BR36767
KEGG:
R04122
|
|
|
|
linalool + 2 reduced_flavodoxin + 2 O2 <=> (6E)-8-oxolinalool + 2 flavin + 3 H2O
|
1.14.14.84
linalool 8-monooxygenase
|
–
|
|
|
BRENDA:
BR36768
KEGG:
R09925
|
|
|
|
isovaleryl-CoA + flavin <=> 3-methylcrotonoyl-CoA + reduced_flavodoxin
|
1.3.8.4
isovaleryl-CoA dehydrogenase
|
–
|
|
|
BRENDA:
BR36848
KEGG:
R04096
|
|
|
|
butyryl-CoA + flavin <=> crotonyl-CoA + reduced_flavodoxin
|
1.3.8.1
short-chain acyl-CoA dehydrogenase
1.3.8.4
isovaleryl-CoA dehydrogenase
1.3.8.7
medium-chain acyl-CoA dehydrogenase
1.3.8.8
long-chain acyl-CoA dehydrogenase
|
–
–
–
–
|
|
|
BRENDA:
BR36851
KEGG:
R01178
|
|
|
|
glutaryl-CoA + flavin <=> crotonyl-CoA + CO2 + reduced_flavodoxin
|
1.3.8.6
glutaryl-CoA dehydrogenase (ETF)
|
–
|
BK
|
|
BRENDA:
BR36856
KEGG:
R02488
|
|
|
|
reduced_flavodoxin + ubiquinone <=> flavin + ubiquinol
|
1.5.5.1
electron-transferring-flavoprotein dehydrogenase
|
–
|
|
|
BRENDA:
BR36912;
BS259373
KEGG:
R04433
|
|
|
|
sarcosine + H2O + flavin <=> glycine + formaldehyde + reduced_flavodoxin
|
1.5.8.3
sarcosine dehydrogenase
|
–
|
K
|
|
BRENDA:
BR36913
KEGG:
R00611
|
|
|
|
N,N-dimethylglycine + tetrahydrofolate + flavin <=> sarcosine + 5,10-methylenetetrahydrofolate + reduced_flavodoxin
|
1.5.8.4
dimethylglycine dehydrogenase
|
–
|
K
|
|
BRENDA:
BR36914
KEGG:
R01565
|
|
|
|
(S)-N-methylcoclaurine + (R)-N-methylcoclaurine + reduced_flavodoxin + O2 <=> Berbamunine + flavin + 2 H2O
|
1.14.19.66
berbamunine synthase
|
–
|
K
|
|
BRENDA:
BR36941
KEGG:
R04694
|
|
|
|
(S)-tetrahydrocolumbamine + reduced_flavodoxin + O2 <=> (S)-canadine + flavin + 2 H2O
|
1.14.19.64
(S)-stylopine synthase
1.14.19.68
(S)-canadine synthase
1.14.19.73
(S)-nandinine synthase
|
–
–
–
|
K
|
|
BRENDA:
BR36946
KEGG:
R04400
|
|
|
|
(R)-reticuline + reduced_flavodoxin + O2 <=> salutaridine + flavin + 2 H2O
|
1.14.19.67
salutaridine synthase
|
–
|
K
|
|
BRENDA:
BR36966
KEGG:
R04696
|
|
|
|
Dimethylamine + H2O + flavin <=> methylamine + formaldehyde + reduced_flavodoxin
|
1.5.8.1
dimethylamine dehydrogenase
|
–
|
BK
|
|
BRENDA:
BR36967
KEGG:
R01588
|
|
|
|
trimethylamine + H2O + flavin <=> Dimethylamine + formaldehyde + reduced_flavodoxin
|
1.5.8.2
trimethylamine dehydrogenase
|
–
|
BK
|
|
BRENDA:
BR36968
KEGG:
R02511
|
|
|
|
(S)-cheilanthifoline + reduced_flavodoxin + O2 <=> (S)-Stylopine + flavin + 2 H2O
|
1.14.19.64
(S)-stylopine synthase
|
–
|
K
|
|
BRENDA:
BR37080
KEGG:
R04690
|
|
|
|
(S)-scoulerine + reduced_flavodoxin + O2 <=> (S)-cheilanthifoline + flavin + 2 H2O
|
1.14.19.65
(S)-cheilanthifoline synthase
|
–
|
K
|
|
BRENDA:
BR37081
KEGG:
R03834
|
|
|
|
5-O-p-coumaroylquinic_acid + reduced_flavodoxin + O2 <=> chlorogenic_acid + flavin + H2O
|
1.14.14.96
5-O-(4-coumaroyl)-D-quinate 3'-monooxygenase
|
–
|
BK
|
|
BRENDA:
BR37109
KEGG:
R04342
|
|
|
|
loganin + reduced_flavodoxin + O2 <=> secologanin + flavin + 2 H2O
|
1.14.19.62
secologanin synthase
|
–
|
K
|
|
BRENDA:
BR40360
KEGG:
R03555
|
|
|
|
squalene + reduced_flavodoxin + O2 <=> (3S)-2,3-epoxy-2,3-dihydrosqualene + flavin + H2O
|
1.14.14.17
squalene monooxygenase
|
–
|
K
|
|
BRENDA:
BR40381
KEGG:
R02874
|
|
|
|
heme + 3 reduced_flavodoxin + 3 O2 <=> Biliverdin + Fe2+ + CO + 3 flavin + 3 H2O
|
1.14.14.18
heme oxygenase (biliverdin-producing)
1.14.99.58
heme oxygenase (biliverdin-IX-beta and delta-forming)
|
–
–
|
BK
|
|
BRENDA:
BR40384
KEGG:
R00311
|
|
|
|
taxa-4(20),11-dien-5alpha-yl_acetate + reduced_flavodoxin + O2 <=> 10beta-hydroxytaxa-4(20),11-dien-5alpha-yl_acetate + flavin + H2O
|
1.14.14.105
taxane 10beta-hydroxylase
|
–
|
BK
|
|
BRENDA:
BR40410
KEGG:
R06309
|
|
|
|
tabersonine + reduced_flavodoxin + O2 <=> 16-hydroxytabersonine + flavin + H2O
|
1.14.14.103
tabersonine 16-hydroxylase
|
–
|
K
|
|
BRENDA:
BR40411
KEGG:
R05855
|
|
|
|
flavonoids + reduced_flavodoxin + O2 <=> a_3''-hydroxyflavonoid + flavin + H2O
|
1.14.14.82
flavonoid 3'-monooxygenase
|
–
|
|
|
BRENDA:
BR40432
KEGG:
R03615
|
|
|
|
vinorine + reduced_flavodoxin + O2 <=> Vomilenine + flavin + H2O
|
1.14.14.104
vinorine hydroxylase
|
–
|
K
|
|
BRENDA:
BR40519
KEGG:
R05877
|
|
|
|
benzoate + reduced_flavodoxin + O2 <=> 4-hydroxybenzoate + flavin + H2O
|
1.14.14.1
unspecific monooxygenase
1.14.14.92
benzoate 4-monooxygenase
|
–
–
|
K
|
|
BRENDA:
BR40521
KEGG:
R01295
|
|
|
|
taxa-4,11-diene + reduced_flavodoxin + O2 <=> taxa-4(20),11-dien-5alpha-ol + flavin + H2O
|
1.14.14.176
taxadiene 5alpha-hydroxylase
|
–
|
BK
|
|
BRENDA:
BR40524
KEGG:
R06306
|
|
|
|
ent-kaur-16-ene + reduced_flavodoxin + O2 <=> ent-kaur-16-en-19-ol + flavin + H2O
|
1.14.14.86
ent-kaurene monooxygenase
|
–
|
K
|
|
BRENDA:
BR40525
KEGG:
R06291
|
|
|
|
ent-kaur-16-en-19-ol + reduced_flavodoxin + O2 <=> ent-kaur-16-en-19-al + flavin + 2 H2O
|
1.14.14.86
ent-kaurene monooxygenase
|
–
|
K
|
|
BRENDA:
BR40526
KEGG:
R06292
|
|
|
|
ent-kaur-16-en-19-al + reduced_flavodoxin + O2 <=> ent-kaur-16-en-19-oate + flavin + H2O
|
1.14.14.86
ent-kaurene monooxygenase
|
–
|
K
|
|
BRENDA:
BR40527
KEGG:
R06293
|
|
|
|
7-deoxyloganate + reduced_flavodoxin + O2 <=> loganic_acid + flavin + H2O
|
1.14.14.85
7-deoxyloganate 7-hydroxylase
|
–
|
K
|
|
BRENDA:
BR40528
KEGG:
R05832
|
|
|
|
ent-kaur-16-en-19-oate + reduced_flavodoxin + O2 <=> ent-7alpha-hydroxykaur-16-en-19-oate + flavin + H2O
|
1.14.14.107
ent-kaurenoic acid monooxygenase
|
–
|
K
|
|
BRENDA:
BR40543
KEGG:
R06294
|
|
|
|
ent-7alpha-hydroxykaur-16-en-19-oate + reduced_flavodoxin + O2 <=> gibberellin_A12_aldehyde + flavin + 2 H2O
|
1.14.14.107
ent-kaurenoic acid monooxygenase
|
–
|
K
|
|
BRENDA:
BR40544
KEGG:
R06295
|
|
|
|
gibberellin_A12_aldehyde + reduced_flavodoxin + O2 <=> gibberellin_A12 + flavin + H2O
|
1.14.14.107
ent-kaurenoic acid monooxygenase
|
–
|
K
|
|
BRENDA:
BR40545
KEGG:
R06297
|
|
|
|
N-hydroxy-L-tyrosine + O2 + reduced_flavodoxin <=> N,N-dihydroxy-L-tyrosine + flavin + H2O
|
1.14.14.36
tyrosine N-monooxygenase
|
–
|
K
|
|
BRENDA:
BR47356
KEGG:
R04460
|
|
|
|
(R)-2-benzylsuccinyl-CoA + flavin <=> (E)-2-benzylidenesuccinyl-CoA + reduced_flavodoxin
|
1.3.8.3
(R)-benzylsuccinyl-CoA dehydrogenase
|
–
|
BK
|
|
BRENDA:
BR47377
KEGG:
R05584
|
|
|
|
(+)-limonene + reduced_flavodoxin + O2 <=> (+)-trans-carveol + flavin + H2O
|
1.14.14.53
(R)-limonene 6-monooxygenase
|
–
|
K
|
|
BRENDA:
BR47606
KEGG:
R06119
|
|
|
|
(6aS,11aS)-2-dimethylallyl-3,6a,9-trihydroxypterocarpan + reduced_flavodoxin + O2 <=> glyceollin_II + flavin + 2 H2O
|
1.14.14.135
glyceollin synthase
|
–
|
K
|
|
BRENDA:
BR48493
KEGG:
R07195
|
|
|
|
a_flavanone + reduced_flavodoxin + O2 <=> a_3''-hydroxyflavanone + flavin + H2O
|
1.14.14.81
flavanoid 3',5'-hydroxylase
|
–
|
|
|
BRENDA:
BR48495
KEGG:
R07369
|
|
|
|
a_3''-hydroxyflavanone + reduced_flavodoxin + O2 <=> a_3'',5''-dihydroxyflavanone + flavin + H2O
|
1.14.14.81
flavanoid 3',5'-hydroxylase
|
–
|
|
|
BRENDA:
BR48496
KEGG:
R07370
|
|
|
|
25-hydroxycholesterol + reduced_flavodoxin + O2 <=> 7alpha,25-Dihydroxycholesterol + flavin + H2O
|
1.14.14.29
25/26-hydroxycholesterol 7alpha-hydroxylase
|
–
|
K
|
|
BRENDA:
BR48561
KEGG:
R07209
|
|
|
|
(24S)-24-hydroxycholesterol + reduced_flavodoxin + O2 <=> (24S)-cholest-5-ene-3beta,7alpha,24-triol + flavin + H2O
|
1.14.14.26
24-hydroxycholesterol 7alpha-hydroxylase
|
–
|
K
|
|
BRENDA:
BR48563
KEGG:
R07208
|
|
|
|
cholesterol + reduced_flavodoxin + O2 <=> (24S)-24-hydroxycholesterol + flavin + H2O
|
1.14.14.25
cholesterol 24-hydroxylase
|
–
|
K
|
|
BRENDA:
BR48564
KEGG:
R07207
|
|
|
|
taurochenodeoxycholate + reduced_flavodoxin + O2 <=> taurohyocholate + flavin + H2O
|
1.14.14.57
taurochenodeoxycholate 6alpha-hydroxylase
|
–
|
|
|
BRENDA:
BR48565
KEGG:
R07205
|
|
|
|
lithocholic_acid + reduced_flavodoxin + O2 <=> hyodeoxycholic_acid + flavin + H2O
|
1.14.14.57
taurochenodeoxycholate 6alpha-hydroxylase
|
–
|
|
|
BRENDA:
BR48566
KEGG:
R07206
|
|
|
|
5beta-cholestane-3alpha,7alpha-diol + reduced_flavodoxin + O2 <=> 5beta-cholestane-3alpha,7alpha,12alpha-triol + flavin + H2O
|
1.14.14.139
5beta-cholestane-3alpha,7alpha-diol 12alpha-hydroxylase
|
–
|
K
|
|
BRENDA:
BR48567
KEGG:
R07204
|
|
|
|
lithocholic_acid + reduced_flavodoxin + O2 <=> 6beta-hydroxylithocholate + flavin + H2O
|
1.14.14.138
lithocholate 6beta-hydroxylase
|
–
|
|
|
BRENDA:
BR48569
KEGG:
R07203
|
|
|
|
abscisic_acid + reduced_flavodoxin + O2 <=> 8''-hydroxyabscisate + flavin + H2O
|
1.14.14.137
(+)-abscisic acid 8'-hydroxylase
|
–
|
K
|
|
BRENDA:
BR48570
KEGG:
R07202
|
|
|
|
an_isoflavone + reduced_flavodoxin + O2 <=> a_2''-hydroxyisoflavone + flavin + H2O
|
1.14.14.90
isoflavone 2'-hydroxylase
|
–
|
|
|
BRENDA:
BR48603
KEGG:
R07371
|
|
|
|
2 ATP + 2 cob(II)yrinic_acid_a,c-diamide + reduced_flavodoxin <=> 2 tripolyphosphate + 2 adenosylcobyrinic_acid_a,c-diamide + flavin
|
2.5.1.17
corrinoid adenosyltransferase
|
–
|
K
|
|
BRENDA:
BR48626
KEGG:
R12184
|
|
|
|
2 ATP + 2 Cobalamin + reduced_flavodoxin <=> 2 tripolyphosphate + 2 adenosylcobalamin + flavin
|
2.5.1.17
corrinoid adenosyltransferase
|
–
|
|
|
BRENDA:
BR48627
KEGG:
R12183
|
|
|
|
10-deoxysarpagine + reduced_flavodoxin + O2 <=> sarpagine + flavin + H2O
|
1.14.14.136
deoxysarpagine hydroxylase
|
–
|
K
|
|
BRENDA:
BR48709
KEGG:
R05828
|
|
|
|
(+)-marmesin + reduced_flavodoxin + O2 <=> psoralen + flavin + acetone + 2 H2O
|
1.14.14.141
psoralen synthase
|
–
|
|
|
BRENDA:
BR48846
KEGG:
R08207
|
|
|
|
sophoraflavanone_B + reduced_flavodoxin + O2 <=> leachianone_G + flavin + H2O
|
1.14.14.142
8-dimethylallylnaringenin 2'-hydroxylase
|
–
|
|
|
BRENDA:
BR48847
KEGG:
R08922
|
|
|
|
(R)-pulegone + reduced_flavodoxin + O2 <=> (+)-menthofuran + flavin + H2O
|
1.14.14.143
(+)-menthofuran synthase
|
–
|
K
|
|
BRENDA:
BR48926
KEGG:
R08923
|
|
|
|
abieta-7,13-diene + reduced_flavodoxin + O2 <=> abietadienol + flavin + H2O
|
1.14.14.144
abieta-7,13-diene hydroxylase
|
–
|
K
|
|
BRENDA:
BR49044
KEGG:
R06351
|
|
|
|
abietadienol + 2 reduced_flavodoxin + 2 O2 <=> abietic_acid + 2 flavin + 3 H2O
|
1.14.14.145
abieta-7,13-dien-18-ol hydroxylase
|
–
|
|
|
BRENDA:
BR49045
KEGG:
R12122
|
|
|
|
geranylgeraniol + reduced_flavodoxin + O2 <=> 18-hydroxygeranylgeraniol + flavin + H2O
|
1.14.14.146
geranylgeraniol 18-hydroxylase
|
–
|
K
|
|
BRENDA:
BR49046
KEGG:
R09122
|
|
|
|
3-epi-6-deoxocathasterone + reduced_flavodoxin + O2 <=> 6-deoxotyphasterol + flavin + H2O
|
1.14.14.147
3-epi-6-deoxocathasterone 23-monooxygenase
|
–
|
K
|
|
BRENDA:
BR49134
KEGG:
R07792
|
|
|
|
(22S,24R)-22-hydroxy-5alpha-ergostan-3-one + reduced_flavodoxin + O2 <=> 3-dehydro-6-deoxoteasterone + flavin + H2O
|
1.14.14.147
3-epi-6-deoxocathasterone 23-monooxygenase
|
–
|
K
|
|
BRENDA:
BR49135
KEGG:
R07791
|
|
|
|
(+)-columbianetin + reduced_flavodoxin + O2 <=> angelicin + flavin + acetone + 2 H2O
|
1.14.14.148
angelicin synthase
|
–
|
|
|
BRENDA:
BR49215
KEGG:
R09002
|
|
|
|
geranylhydroquinone + reduced_flavodoxin + O2 <=> 3''''-hydroxygeranylhydroquinone + flavin + H2O
|
1.14.14.174
geranylhydroquinone 3''-hydroxylase
|
–
|
K
|
|
BRENDA:
BR49271
KEGG:
R09042
|
|
|
|
L-isoleucine + 2 reduced_flavodoxin + 2 O2 <=> (1E,2S)-2-methylbutanal_oxime + 2 flavin + CO2 + 3 H2O
|
1.14.14.39
isoleucine N-monooxygenase
|
–
|
K
|
|
BRENDA:
BR49376
KEGG:
R09403
|
|
|
|
L-isoleucine + reduced_flavodoxin + O2 <=> N-hydroxy-L-isoleucine + flavin + H2O
|
1.14.14.38
valine N-monooxygenase
1.14.14.39
isoleucine N-monooxygenase
|
–
–
|
K
|
|
BRENDA:
BR49377
KEGG:
R10027
|
|
|
|
N-hydroxy-L-isoleucine + reduced_flavodoxin + O2 <=> N,N-dihydroxy-L-isoleucine + flavin + H2O
|
1.14.14.38
valine N-monooxygenase
1.14.14.39
isoleucine N-monooxygenase
|
–
–
|
K
|
|
BRENDA:
BR49378
KEGG:
R10028
|
|
|
|
L-valine + 2 reduced_flavodoxin + 2 O2 <=> (E/Z)-isobutyraldoxime + 2 flavin + CO2 + 3 H2O
|
1.14.14.38
valine N-monooxygenase
|
–
|
K
|
|
BRENDA:
BR49380
KEGG:
R08663
|
|
|
|
L-valine + reduced_flavodoxin + O2 <=> N-hydroxy-L-valine + flavin + H2O
|
1.14.14.38
valine N-monooxygenase
1.14.14.39
isoleucine N-monooxygenase
|
–
–
|
K
|
|
BRENDA:
BR49381
KEGG:
R10031
|
|
|
|
N-hydroxy-L-valine + reduced_flavodoxin + O2 <=> N,N-dihydroxy-L-valine + flavin + H2O
|
1.14.14.38
valine N-monooxygenase
1.14.14.39
isoleucine N-monooxygenase
|
–
–
|
K
|
|
BRENDA:
BR49382
KEGG:
R10032
|
|
|
|
5-epiaristolochene + 2 reduced_flavodoxin + 2 O2 <=> capsidiol + 2 flavin + 2 H2O
|
1.14.14.149
5-epiaristolochene 1,3-dihydroxylase
|
–
|
K
|
|
BRENDA:
BR49418
KEGG:
R09573
|
|
|
|
germacra-1(10),4,11(13)-trien-12-oate + reduced_flavodoxin + O2 <=> (+)-costunolide + flavin + 2 H2O
|
1.14.14.150
costunolide synthase
|
–
|
K
|
|
BRENDA:
BR49419
KEGG:
R09575
|
|
|
|
(-)-vetispiradiene + reduced_flavodoxin + O2 <=> solavetivol + flavin + H2O
|
1.14.14.151
premnaspirodiene oxygenase
|
–
|
K
|
|
BRENDA:
BR49420
KEGG:
R09576
|
|
|
|
solavetivol + reduced_flavodoxin + O2 <=> solavetivone + flavin + 2 H2O
|
1.14.14.151
premnaspirodiene oxygenase
|
–
|
K
|
|
BRENDA:
BR49421
KEGG:
R09577
|
|
|
|
Calycosin + reduced_flavodoxin + O2 <=> pseudobaptigenin + flavin + 2 H2O
|
1.14.19.63
pseudobaptigenin synthase
|
–
|
K
|
|
BRENDA:
BR49422
KEGG:
R07745
|
|
|
|
Pratensein + reduced_flavodoxin + O2 <=> 5-hydroxypseudobaptigenin + flavin + 2 H2O
|
1.14.19.63
pseudobaptigenin synthase
|
–
|
K
|
|
BRENDA:
BR49423
KEGG:
R09602
|
|
|
|
germacrene_A + 3 reduced_flavodoxin + 3 O2 <=> germacra-1(10),4,11(13)-trien-12-oate + 3 flavin + 4 H2O
|
1.14.14.95
germacrene A hydroxylase
|
–
|
|
|
BRENDA:
BR49588
KEGG:
R12128
|
|
|
|
L-phenylalanine + 2 reduced_flavodoxin + 2 O2 <=> (E)-phenylacetaldoxime + 2 flavin + CO2 + 3 H2O
|
1.14.14.40
phenylalanine N-monooxygenase
|
–
|
K
|
|
BRENDA:
BR49589
KEGG:
R09578
|
|
|
|
L-phenylalanine + reduced_flavodoxin + O2 <=> N-hydroxy-L-phenylalanine + flavin + H2O
|
1.14.14.40
phenylalanine N-monooxygenase
|
–
|
K
|
|
BRENDA:
BR49590
KEGG:
R09579
|
|
|
|
N-hydroxy-L-phenylalanine + reduced_flavodoxin + O2 <=> N,N-dihydroxy-L-phenylalanine + flavin + H2O
|
1.14.14.40
phenylalanine N-monooxygenase
|
–
|
K
|
|
BRENDA:
BR49591
KEGG:
R09580
|
|
|
|
L-tryptophan + 2 reduced_flavodoxin + 2 O2 <=> (E,Z)-indolyl-3-acetaldoxime + 2 flavin + CO2 + 3 H2O
|
1.14.14.156
tryptophan N-monooxygenase
|
–
|
K
|
|
BRENDA:
BR49593
KEGG:
R08160
|
|
|
|
L-tryptophan + reduced_flavodoxin + O2 <=> N-hydroxy-L-tryptophan + flavin + H2O
|
1.14.14.156
tryptophan N-monooxygenase
|
–
|
|
|
BRENDA:
BR49594
KEGG:
R09583
|
|
|
|
N-hydroxy-L-tryptophan + reduced_flavodoxin + O2 <=> N,N-dihydroxy-L-tryptophan + flavin + H2O
|
1.14.14.156
tryptophan N-monooxygenase
|
–
|
|
|
BRENDA:
BR49595
KEGG:
R09584
|
|
|
|
beta-amyrin + reduced_flavodoxin + O2 <=> 24-hydroxy-beta-amyrin + flavin + H2O
|
1.14.14.134
beta-amyrin 24-hydroxylase
|
–
|
K
|
|
BRENDA:
BR49606
KEGG:
R09604
|
|
|
|
sophoradiol + reduced_flavodoxin + O2 <=> soyasapogenol_B + flavin + H2O
|
1.14.14.134
beta-amyrin 24-hydroxylase
|
–
|
|
|
BRENDA:
BR49607
KEGG:
R09605
|
|
|
|
alpha-carotene + reduced_flavodoxin + O2 <=> alpha-cryptoxanthin + flavin + H2O
|
1.14.14.158
carotenoid epsilon hydroxylase
|
–
|
K
|
|
BRENDA:
BR49609
KEGG:
R07850
|
|
|
|
beta-amyrin + 2 reduced_flavodoxin + 2 O2 <=> 11-oxo-beta-amyrin + 2 flavin + 3 H2O
|
1.14.14.152
beta-amyrin 11-oxidase
|
–
|
|
|
BRENDA:
BR49822
KEGG:
R09817
|
|
|
|
beta-amyrin + reduced_flavodoxin + O2 <=> 11alpha-hydroxy-beta-amyrin + flavin + H2O
|
1.14.14.152
beta-amyrin 11-oxidase
|
–
|
|
|
BRENDA:
BR49823
KEGG:
R09815
|
|
|
|
11alpha-hydroxy-beta-amyrin + reduced_flavodoxin + O2 <=> 11-oxo-beta-amyrin + flavin + 2 H2O
|
1.14.14.152
beta-amyrin 11-oxidase
|
–
|
|
|
BRENDA:
BR49824
KEGG:
R09816
|
|
|
|
liquiritigenin + O2 + reduced_flavodoxin <=> 2,4'',7-trihydroxyisoflavanone + H2O + flavin
|
1.14.14.87
2-hydroxyisoflavanone synthase
|
–
|
K
|
|
BRENDA:
BR49825
KEGG:
R07777
|
|
|
|
abietadienol + reduced_flavodoxin + O2 <=> abieta-7,13-dien-18,18-diol + flavin + H2O
|
1.14.14.145
abieta-7,13-dien-18-ol hydroxylase
|
–
|
|
|
BRENDA:
BR49967
KEGG:
R10077
|
|
|
|
indole + reduced_flavodoxin + O2 <=> indolin-2-one + flavin + H2O
|
1.14.14.153
indole-2-monooxygenase
|
–
|
K
|
|
BRENDA:
BR49969
KEGG:
R07403
|
|
|
|
indolin-2-one + reduced_flavodoxin + O2 <=> 3-hydroxyindolin-2-one + flavin + H2O
|
1.14.14.157
indolin-2-one monooxygenase
|
–
|
K
|
|
BRENDA:
BR49970
KEGG:
R07421
|
|
|
|
3-hydroxyindolin-2-one + reduced_flavodoxin + O2 <=> 2-hydroxy-2H-1,4-benzoxazin-3(4H)-one + flavin + H2O
|
1.14.14.109
3-hydroxyindolin-2-one monooxygenase
|
–
|
K
|
|
BRENDA:
BR49971
KEGG:
R07422
|
|
|
|
ent-isokaurene + 2 O2 + 2 reduced_flavodoxin <=> ent-isokaurene-2beta,3beta-diol + flavin + 2 H2O
|
1.14.14.76
ent-isokaurene C2/C3-hydroxylase
|
–
|
|
|
BRENDA:
BR49975
KEGG:
R12058
|
|
|
|
9beta-pimara-7,15-diene + 3 O2 + 3 reduced_flavodoxin <=> 9beta-pimara-7,15-dien-19-oate + 3 flavin + 4 H2O
|
1.14.14.111
9beta-pimara-7,15-diene oxidase
|
–
|
K
|
|
BRENDA:
BR49976
KEGG:
R09865
|
|
|
|
9beta-pimara-7,15-diene + O2 + reduced_flavodoxin <=> 9beta-pimara-7,15-dien-19-ol + flavin + H2O
|
1.14.14.111
9beta-pimara-7,15-diene oxidase
|
–
|
|
|
BRENDA:
BR49977
KEGG:
R09862
|
|
|
|
9beta-pimara-7,15-dien-19-ol + O2 + reduced_flavodoxin <=> 9beta-pimara-7,15-dien-19-al + flavin + 2 H2O
|
1.14.14.111
9beta-pimara-7,15-diene oxidase
|
–
|
|
|
BRENDA:
BR49978
KEGG:
R09863
|
|
|
|
9beta-pimara-7,15-dien-19-al + O2 + reduced_flavodoxin <=> 9beta-pimara-7,15-dien-19-oate + flavin + H2O
|
1.14.14.111
9beta-pimara-7,15-diene oxidase
|
–
|
|
|
BRENDA:
BR49979
KEGG:
R09864
|
|
|
|
ent-cassa-12,15-diene + O2 + reduced_flavodoxin <=> ent-11beta-hydroxycassa-12,15-diene + flavin + H2O
|
1.14.14.112
ent-cassa-12,15-diene 11-hydroxylase
|
–
|
K
|
|
BRENDA:
BR49980
KEGG:
R09866
|
|
|
|
alpha-humulene + O2 + reduced_flavodoxin <=> 10-hydroxy-alpha-humulene + flavin + H2O
|
1.14.14.113
alpha-humulene 10-hydroxylase
|
–
|
|
|
BRENDA:
BR50023
KEGG:
R09934
|
|
|
|
linalool + reduced_flavodoxin + O2 <=> (6E)-8-hydroxylinalool + flavin + H2O
|
1.14.14.84
linalool 8-monooxygenase
|
–
|
K
|
|
BRENDA:
BR50024
KEGG:
R04366;
R09923
|
|
|
|
(6E)-8-hydroxylinalool + reduced_flavodoxin + O2 <=> (6E)-8-oxolinalool + flavin + 2 H2O
|
1.14.14.84
linalool 8-monooxygenase
|
–
|
K
|
|
BRENDA:
BR50025
KEGG:
R09924
|
|
|
|
geraniol + reduced_flavodoxin + O2 <=> (6E)-8-hydroxygeraniol + flavin + H2O
|
1.14.14.1
unspecific monooxygenase
1.14.14.83
geraniol 8-hydroxylase
|
–
–
|
K
|
|
BRENDA:
BR50026
KEGG:
R08785
|
|
|
|
glutaryl-CoA + flavin <=> glutaconyl-CoA + reduced_flavodoxin
|
1.3.8.6
glutaryl-CoA dehydrogenase (ETF)
|
–
|
B
|
|
BRENDA:
BR50093
KEGG:
R10074
|
|
|
|
1,8-cineole + reduced_flavodoxin + O2 <=> 2-exo-hydroxy-1,8-cineole + flavin + H2O
|
1.14.14.133
1,8-cineole 2-endo-monooxygenase
1.14.14.56
1,8-cineole 2-exo-monooxygenase
|
–
–
|
|
|
BRENDA:
BR50103;
BS418195
KEGG:
R10076
|
|
|
|
amorpha-4,11-diene + 3 O2 + 3 reduced_flavodoxin <=> artemisinate + 3 flavin + 4 H2O
|
1.14.14.114
amorpha-4,11-diene 12-monooxygenase
|
–
|
|
|
BRENDA:
BR50104
KEGG:
R10026
|
|
|
|
artemisinic_alcohol + O2 + reduced_flavodoxin <=> artemisinic_aldehyde + flavin + 2 H2O
|
1.14.14.114
amorpha-4,11-diene 12-monooxygenase
|
–
|
B
|
|
BRENDA:
BR50105
KEGG:
R10024
|
|
|
|
artemisinic_aldehyde + O2 + reduced_flavodoxin <=> artemisinate + flavin + H2O
|
1.14.14.114
amorpha-4,11-diene 12-monooxygenase
|
–
|
B
|
|
BRENDA:
BR50106
KEGG:
R10025
|
|
|
|
vitamin_D3 + O2 + reduced_flavodoxin <=> 25-hydroxyvitamin_D3 + flavin + H2O
|
1.14.14.24
vitamin D 25-hydroxylase
|
–
|
K
|
|
BRENDA:
BR50107
KEGG:
R03611
|
|
|
|
amorpha-4,11-diene + O2 + reduced_flavodoxin <=> artemisinic_alcohol + flavin + H2O
|
1.14.14.114
amorpha-4,11-diene 12-monooxygenase
|
–
|
B
|
|
BRENDA:
BR50356
KEGG:
R10023
|
|
|
|
ent-kaur-16-en-19-oate + 3 reduced_flavodoxin + 3 O2 <=> gibberellin_A12 + 3 flavin + 4 H2O
|
1.14.14.107
ent-kaurenoic acid monooxygenase
|
–
|
|
|
BRENDA:
BR50357
KEGG:
R10067
|
|
|
|
stearoyl-[acyl-carrier_protein] + 2 reduced_flavodoxin + 3 O2 <=> pimeloyl-[acyl-carrier_protein] + an_n-alkanal + 2 flavin + 3 H2O
|
1.14.14.46
pimeloyl-[acyl-carrier protein] synthase
|
–
|
K
|
|
BRENDA:
BR50373
KEGG:
R10123
|
|
|
|
naringenin + O2 + reduced_flavodoxin <=> 2,4'',5,7-tetrahydroxyisoflavanone + H2O + flavin
|
1.14.14.87
2-hydroxyisoflavanone synthase
|
–
|
K
|
|
BRENDA:
BR50515
KEGG:
R07778
|
|
|
|
11-oxo-beta-amyrin + 3 O2 + 3 reduced_flavodoxin <=> glycyrrhetinic_acid + 3 flavin + 4 H2O
|
1.14.14.115
11-oxo-beta-amyrin 30-oxidase
|
–
|
|
|
BRENDA:
BR50517
KEGG:
R10316
|
|
|
|
11-oxo-beta-amyrin + O2 + reduced_flavodoxin <=> 30-hydroxy-11-oxo-beta-amyrin + flavin + H2O
|
1.14.14.115
11-oxo-beta-amyrin 30-oxidase
|
–
|
|
|
BRENDA:
BR50518
KEGG:
R10313
|
|
|
|
30-hydroxy-11-oxo-beta-amyrin + O2 + reduced_flavodoxin <=> glycyrrhetaldehyde + flavin + 2 H2O
|
1.14.14.115
11-oxo-beta-amyrin 30-oxidase
|
–
|
|
|
BRENDA:
BR50519
KEGG:
R10314
|
|
|
|
glycyrrhetaldehyde + O2 + reduced_flavodoxin <=> glycyrrhetinic_acid + flavin + H2O
|
1.14.14.115
11-oxo-beta-amyrin 30-oxidase
|
–
|
|
|
BRENDA:
BR50520
KEGG:
R10315
|
|
|
|
(1''S)-averantin + reduced_flavodoxin + O2 <=> (1''S,5''S)-5''-hydroxyaverantin + flavin + H2O
|
1.14.14.116
averantin hydroxylase
|
–
|
K
|
|
BRENDA:
BR50521
KEGG:
R10317
|
|
|
|
(1''S)-averantin + reduced_flavodoxin + O2 <=> (1''S,5''R)-5''-hydroxyaverantin + flavin + H2O
|
1.14.14.116
averantin hydroxylase
|
–
|
K
|
|
BRENDA:
BR50522
KEGG:
R10318
|
|
|
|
8-O-methylsterigmatocystin + 2 reduced_flavodoxin + 2 O2 <=> aflatoxin_B1 + 2 flavin + H2O + methanol + CO2
|
1.14.14.117
aflatoxin B synthase
|
–
|
K
|
|
BRENDA:
BR50523
KEGG:
R10319
|
|
|
|
8-O-methyldihydrosterigmatocystin + 2 reduced_flavodoxin + 2 O2 <=> Aflatoxin_B2 + 2 flavin + H2O + methanol + CO2
|
1.14.14.117
aflatoxin B synthase
|
–
|
K
|
|
BRENDA:
BR50524
KEGG:
R10320
|
|
|
|
tryprostatin_B + reduced_flavodoxin + O2 <=> 6-hydroxytryprostatin_B + flavin + H2O
|
1.14.14.118
tryprostatin B 6-hydroxylase
|
–
|
BK
|
|
BRENDA:
BR50525
KEGG:
R10321
|
|
|
|
fumitremorgin_C + 2 reduced_flavodoxin + 2 O2 <=> 12alpha,13alpha-dihydroxyfumitremorgin_C + 2 flavin + 2 H2O
|
1.14.14.119
fumitremorgin C monooxygenase
|
–
|
BK
|
|
BRENDA:
BR50576
KEGG:
R10414
|
|
|
|
tryprostatin_A + reduced_flavodoxin + O2 <=> fumitremorgin_C + flavin + 2 H2O
|
1.14.19.71
fumitremorgin C synthase
|
–
|
BK
|
|
BRENDA:
BR50590
KEGG:
R10416
|
|
|
|
testosterone + 3 O2 + 3 reduced_flavodoxin <=> 17beta-estradiol + formate + 4 H2O + 3 flavin
|
1.14.14.14
aromatase
|
–
|
|
|
BRENDA:
BR50742
KEGG:
R10511
|
|
|
|
testosterone + O2 + reduced_flavodoxin <=> 19-hydroxytestosterone + H2O + flavin
|
1.14.14.14
aromatase
|
–
|
K
|
|
BRENDA:
BR50743
KEGG:
R02501
|
|
|
|
19-hydroxytestosterone + O2 + reduced_flavodoxin <=> 19-oxotestosterone + 2 H2O + flavin
|
1.14.14.14
aromatase
|
–
|
K
|
|
BRENDA:
BR50744
KEGG:
R04761
|
|
|
|
19-oxotestosterone + O2 + reduced_flavodoxin <=> 17beta-estradiol + formate + H2O + flavin
|
1.14.14.14
aromatase
|
–
|
K
|
|
BRENDA:
BR50745
KEGG:
R03087
|
|
|
|
4-androstene-3,17-dione + 3 O2 + 3 reduced_flavodoxin <=> estrone + formate + 4 H2O + 3 flavin
|
1.14.14.14
aromatase
|
–
|
|
|
BRENDA:
BR50746
KEGG:
R10515
|
|
|
|
4-androstene-3,17-dione + O2 + reduced_flavodoxin <=> 19-hydroxyandrost-4-ene-3,17-dione + H2O + flavin
|
1.14.14.14
aromatase
|
–
|
K
|
|
BRENDA:
BR50747;
BS425925
KEGG:
R01840
|
|
|
|
19-hydroxyandrost-4-ene-3,17-dione + O2 + reduced_flavodoxin <=> 19-oxoandrost-4-ene-3,17-dione + 2 H2O + flavin
|
1.14.14.14
aromatase
|
–
|
K
|
|
BRENDA:
BR50748;
BS425315
KEGG:
R04759
|
|
|
|
19-oxoandrost-4-ene-3,17-dione + O2 + reduced_flavodoxin <=> estrone + formate + H2O + flavin
|
1.14.14.14
aromatase
|
–
|
K
|
|
BRENDA:
BR50749;
BS425316
KEGG:
R02351
|
|
|
|
cyclohex-1-ene-1-carbonyl-CoA + flavin <=> cyclohexa-1,5-diene-1-carbonyl-CoA + reduced_flavodoxin
|
1.3.8.10
cyclohex-1-ene-1-carbonyl-CoA dehydrogenase
|
–
|
BK
|
|
BRENDA:
BR50781
KEGG:
R09252
|
|
|
|
cyclohexanecarboxyl-CoA + flavin <=> cyclohex-1-ene-1-carbonyl-CoA + reduced_flavodoxin
|
1.3.8.11
cyclohexane-1-carbonyl-CoA dehydrogenase (electron-transfer flavoprotein)
|
–
|
BK
|
|
BRENDA:
BR50782
KEGG:
R10601
|
|
|
|
(20S)-dammarenediol + reduced_flavodoxin + O2 <=> protopanaxadiol + flavin + H2O
|
1.14.14.120
dammarenediol 12-hydroxylase
|
–
|
B
|
|
BRENDA:
BR50786
KEGG:
R10540
|
|
|
|
protopanaxadiol + reduced_flavodoxin + O2 <=> protopanaxatriol + flavin + H2O
|
1.14.14.121
protopanaxadiol 6-hydroxylase
|
–
|
B
|
|
BRENDA:
BR50787
KEGG:
R10591
|
|
|
|
abieta-8,11,13-triene + reduced_flavodoxin + O2 <=> ferruginol + flavin + H2O
|
1.14.14.175
ferruginol synthase
|
–
|
K
|
|
BRENDA:
BR51028;
BS454240
KEGG:
R12652
|
|
|
|
ent-sandaracopimara-8(14),15-diene + reduced_flavodoxin + O2 <=> ent-sandaracopimaradien-3beta-ol + flavin + H2O
|
1.14.14.70
ent-sandaracopimaradiene 3-hydroxylase
|
–
|
BK
|
|
BRENDA:
BR51029
KEGG:
R11656
|
|
|
|
ent-sandaracopimaradien-3beta-ol + reduced_flavodoxin + O2 <=> oryzalexin_E + flavin + H2O
|
1.14.14.122
oryzalexin E synthase
|
–
|
BK
|
|
BRENDA:
BR51030
KEGG:
R11657
|
|
|
|
ent-sandaracopimaradien-3beta-ol + reduced_flavodoxin + O2 <=> oryzalexin_D + flavin + H2O
|
1.14.14.123
oryzalexin D synthase
|
–
|
BK
|
|
BRENDA:
BR51031
KEGG:
R11658
|
|
|
|
vitamin_K + reduced_flavodoxin + O2 <=> omega-hydroxyphylloquinone + flavin + H2O
|
1.14.14.78
phylloquinone omega-hydroxylase
|
–
|
|
|
BRENDA:
BR51032
KEGG:
R10728
|
|
|
|
dihydromonacolin_L_acid + O2 + reduced_flavodoxin <=> monacolin_L_acid + flavin + 2 H2O
|
1.14.14.124
dihydromonacolin L hydroxylase
|
–
|
|
|
BRENDA:
BR51072
KEGG:
R10793
|
|
|
|
dihydromonacolin_L_acid + O2 + reduced_flavodoxin <=> 3alpha-hydroxy-3,5-dihydromonacolin_L_acid + flavin + H2O
|
1.14.14.124
dihydromonacolin L hydroxylase
|
–
|
K
|
|
BRENDA:
BR51073
KEGG:
R10791
|
|
|
|
monacolin_L_acid + O2 + reduced_flavodoxin <=> monacolin_J_acid + flavin + H2O
|
1.14.14.125
monacolin L hydroxylase
|
–
|
K
|
|
BRENDA:
BR51075
KEGG:
R10794
|
|
|
|
docosahexaenoic_acid + reduced_flavodoxin + O2 <=> 22-hydroxydocosahexaenoic_acid + flavin + H2O
|
1.14.14.1
unspecific monooxygenase
1.14.14.79
docosahexaenoic acid omega-hydroxylase
|
–
–
|
|
|
BRENDA:
BR51076
KEGG:
R10795
|
|
|
|
(2S)-methylsuccinyl-CoA + flavin <=> 2-methylfumaryl-CoA + reduced_flavodoxin
|
1.3.8.12
(2S)-methylsuccinyl-CoA dehydrogenase
|
–
|
BK
|
|
BRENDA:
BR51215
KEGG:
R09293
|
|
|
|
beta-amyrin + O2 + reduced_flavodoxin <=> erythrodiol + flavin + H2O
|
1.14.14.126
beta-amyrin 28-monooxygenase
|
–
|
|
|
BRENDA:
BR51294
KEGG:
R10921
|
|
|
|
erythrodiol + O2 + reduced_flavodoxin <=> oleanolic_aldehyde + flavin + 2 H2O
|
1.14.14.126
beta-amyrin 28-monooxygenase
|
–
|
|
|
BRENDA:
BR51295
KEGG:
R10922
|
|
|
|
oleanolic_aldehyde + O2 + reduced_flavodoxin <=> oleanolic_acid + flavin + H2O
|
1.14.14.126
beta-amyrin 28-monooxygenase
|
–
|
|
|
BRENDA:
BR51296
KEGG:
R10923
|
|
|
|
beta-amyrin + 3 O2 + 3 reduced_flavodoxin <=> oleanolic_acid + 3 flavin + 4 H2O
|
1.14.14.115
11-oxo-beta-amyrin 30-oxidase
1.14.14.126
beta-amyrin 28-monooxygenase
|
–
–
|
B
|
|
BRENDA:
BR51297
KEGG:
R10924
|
|
|
|
methyl_farnesoate + reduced_flavodoxin + O2 <=> juvenile_hormone_III + flavin + H2O
|
1.14.14.127
methyl farnesoate epoxidase
|
–
|
K
|
|
BRENDA:
BR51298
KEGG:
R08148
|
|
|
|
farnesoic_acid + reduced_flavodoxin + O2 <=> juvenile_hormone_III_acid + flavin + H2O
|
1.14.14.128
farnesoate epoxidase
|
–
|
K
|
|
BRENDA:
BR51300
KEGG:
R10925
|
|
|
|
oleoyl-CoA + reduced_flavodoxin + O2 <=> 18-hydroxyoleoyl-CoA + flavin + H2O
|
1.14.14.129
long-chain acyl-CoA omega-monooxygenase
|
–
|
|
|
BRENDA:
BR51355
KEGG:
R10999
|
|
|
|
linoleoyl-CoA + reduced_flavodoxin + O2 <=> 18-hydroxylinoleoyl-CoA + flavin + H2O
|
1.14.14.129
long-chain acyl-CoA omega-monooxygenase
|
–
|
|
|
BRENDA:
BR51356
KEGG:
R11000
|
|
|
|
palmitate + reduced_flavodoxin + O2 <=> an_omega-hydroxy-long-chain_fatty_acid + flavin + H2O
|
1.14.14.80
long-chain fatty acid omega-monooxygenase
|
–
|
|
|
BRENDA:
BR51357
KEGG:
R12072
|
|
|
|
laurate + reduced_flavodoxin + O2 <=> 7-hydroxydodecanoate + flavin + H2O
|
1.14.14.130
laurate 7-monooxygenase
|
–
|
|
|
BRENDA:
BR51494
KEGG:
R11054
|
|
|
|
myrcene + reduced_flavodoxin + O2 <=> (4R)-ipsdienol + flavin + H2O
|
1.14.14.31
ipsdienol synthase
|
–
|
K
|
|
BRENDA:
BR51495
KEGG:
R11055
|
|
|
|
(-)-bursehernin + reduced_flavodoxin + O2 <=> (-)-5''-demethylyatein + flavin + H2O
|
1.14.14.131
bursehernin 5'-monooxygenase
|
–
|
K
|
|
BRENDA:
BR51573
KEGG:
R11211
|
|
|
|
(-)-4''-demethyldeoxypodophyllotoxin + reduced_flavodoxin + O2 <=> (-)-4''-demethylepipodophyllotoxin + flavin + H2O
|
1.14.14.132
(-)-4'-demethyl-deoxypodophyllotoxin 4-hydroxylase
|
–
|
|
|
BRENDA:
BR51574
KEGG:
R11212
|
|
|
|
(-)-matairesinol + reduced_flavodoxin + O2 <=> (-)-pluviatolide + flavin + 2 H2O
|
1.14.19.72
(-)-pluviatolide synthase
|
–
|
K
|
|
BRENDA:
BR51591
KEGG:
R11222
|
|
|
|
17alpha-hydroxypregnenolone + reduced_flavodoxin + O2 <=> dehydroepiandrosterone + acetate + flavin + H2O
|
1.14.14.32
17alpha-hydroxyprogesterone deacetylase
|
–
|
K
|
|
BRENDA:
BR51745
KEGG:
R08517
|
|
|
|
(S)-scoulerine + reduced_flavodoxin + O2 <=> (S)-nandinine + flavin + 2 H2O
|
1.14.19.64
(S)-stylopine synthase
1.14.19.73
(S)-nandinine synthase
|
–
–
|
|
|
BRENDA:
BR51746
KEGG:
R11405
|
|
|
|
L-tyrosine + 2 O2 + 2 reduced_flavodoxin <=> p-hydroxyphenylacetaldoxime + 2 flavin + CO2 + 3 H2O
|
1.14.14.36
tyrosine N-monooxygenase
1.14.14.40
phenylalanine N-monooxygenase
|
–
–
|
K
|
|
BRENDA:
BR51798
KEGG:
R10671
|
|
|
|
4-Hydroxyphenylacetonitrile + reduced_flavodoxin + O2 <=> (S)-4-hydroxymandelonitrile + flavin + H2O
|
1.14.14.37
4-hydroxyphenylacetaldehyde oxime monooxygenase
|
–
|
|
|
BRENDA:
BR51801
KEGG:
R02708
|
|
|
|
4''-O-methylnorbelladine + reduced_flavodoxin + O2 <=> (10bS,4aR)-noroxomaritidine + flavin + 2 H2O
|
1.14.19.50
noroxomaritidine synthase
|
–
|
K
|
|
BRENDA:
BR51838
KEGG:
R11483
|
|
|
|
4''-O-methylnorbelladine + reduced_flavodoxin + O2 <=> (4aS,10bR)-8-hydroxy-9-methoxy-4,4a-dihydro-3H,6H-5,10b-ethanophenanthridin-3-one + flavin + 2 H2O
|
1.14.19.50
noroxomaritidine synthase
|
–
|
K
|
|
BRENDA:
BR51839
KEGG:
R11482
|
|
|
|
gamma-butyrobetainyl-CoA + flavin <=> (E)-4-(trimethylammonio)but-2-enoyl-CoA + reduced_flavodoxin
|
1.3.8.13
crotonobetainyl-CoA reductase
|
–
|
B
|
|
BRENDA:
BR51924
KEGG:
R11600
|
|
|
|
(E)-2-methylbutanal_oxime + reduced_flavodoxin + O2 <=> 2-Methyl-2-hydroxybutyronitrile + flavin + 2 H2O
|
1.14.14.41
(E)-2-methylbutanal oxime monooxygenase
|
–
|
|
|
BRENDA:
BR51939
KEGG:
R11597
|
|
|
|
2-methylbutyronitrile + reduced_flavodoxin + O2 <=> 2-Methyl-2-hydroxybutyronitrile + flavin + H2O
|
1.14.14.41
(E)-2-methylbutanal oxime monooxygenase
|
–
|
K
|
|
BRENDA:
BR51942
KEGG:
R11640
|
|
|
|
(E/Z)-isobutyraldoxime + reduced_flavodoxin + O2 <=> acetone_cyanohydrin + flavin + 2 H2O
|
1.14.14.41
(E)-2-methylbutanal oxime monooxygenase
|
–
|
|
|
BRENDA:
BR51943
KEGG:
R11598
|
|
|
|
Isobutyronitrile + reduced_flavodoxin + O2 <=> acetone_cyanohydrin + flavin + H2O
|
1.14.14.41
(E)-2-methylbutanal oxime monooxygenase
|
–
|
K
|
|
BRENDA:
BR51946
KEGG:
R11642
|
|
|
|
an_omega-(methylthio)-(E)-alkanal_oxime + reduced_flavodoxin + glutathione + O2 <=> (E)-1-(glutathione-S-yl)-omega-(methylthio)alkylhydroximate + flavin + 2 H2O
|
1.14.14.40
phenylalanine N-monooxygenase
1.14.14.43
(methylsulfanyl)alkanaldoxime N-monooxygenase
1.14.14.45
aromatic aldoxime N-monooxygenase
|
–
–
–
|
|
|
BRENDA:
BR51951;
BS438185
KEGG:
R11650
|
|
|
|
an_omega-(methylthio)-(E)-alkanal_oxime + reduced_flavodoxin + O2 <=> a_1-aci-nitro-omega-(methylthio)alkane + flavin + H2O
|
1.14.14.43
(methylsulfanyl)alkanaldoxime N-monooxygenase
|
–
|
|
|
BRENDA:
BR51952
KEGG:
R11651
|
|
|
|
(E)-phenylacetaldoxime + reduced_flavodoxin + O2 <=> (R)-mandelonitrile + flavin + 2 H2O
|
1.14.14.44
phenylacetaldehyde oxime monooxygenase
|
–
|
|
|
BRENDA:
BR52032
KEGG:
R11732
|
|
|
|
phenylacetonitrile + reduced_flavodoxin + O2 <=> (R)-mandelonitrile + flavin + H2O
|
1.14.14.44
phenylacetaldehyde oxime monooxygenase
1.14.14.77
phenylacetonitrile alpha-monooxygenase
|
–
–
|
K
|
|
BRENDA:
BR52035
KEGG:
R11733
|
|
|
|
(E)-phenylacetaldoxime + reduced_flavodoxin + glutathione + O2 <=> S-[(Z)-N-hydroxy(phenyl)acetimidoyl]-L-glutathione + flavin + 2 H2O
|
1.14.14.45
aromatic aldoxime N-monooxygenase
|
–
|
|
|
BRENDA:
BR52039
KEGG:
R11737
|
|
|
|
(E)-phenylacetaldoxime + reduced_flavodoxin + O2 <=> 1-aci-nitro-2-phenylethane + flavin + H2O
|
1.14.14.43
(methylsulfanyl)alkanaldoxime N-monooxygenase
1.14.14.45
aromatic aldoxime N-monooxygenase
|
–
–
|
|
|
BRENDA:
BR52040
KEGG:
R11738
|
|
|
|
(S)-reticuline + reduced_flavodoxin + O2 <=> (S)-corytuberine + flavin + 2 H2O
|
1.14.19.51
(S)-corytuberine synthase
|
–
|
K
|
|
BRENDA:
BR52042
KEGG:
R08790
|
|
|
|
a_jasmonoyl-L-amino_acid + reduced_flavodoxin + O2 <=> a_12-hydroxyjasmonoyl-L-amino_acid + flavin + H2O
|
1.14.14.48
jasmonoyl-L-amino acid 12-hydroxylase
|
–
|
|
|
BRENDA:
BR52141
KEGG:
R11806
|
|
|
|
a_12-hydroxyjasmonoyl-L-amino_acid + 2 reduced_flavodoxin + 2 O2 <=> a_12-hydroxy-12-oxojasmonoyl-L-amino_acid + 2 flavin + 3 H2O
|
1.14.14.49
12-hydroxyjasmonoyl-L-amino acid 12-hydroxylase
|
–
|
|
|
BRENDA:
BR52142
KEGG:
R11807
|
|
|
|
a_12-hydroxyjasmonoyl-L-amino_acid + reduced_flavodoxin + O2 <=> a_12-oxojasmonoyl-L-amino_acid + flavin + 2 H2O
|
1.14.14.49
12-hydroxyjasmonoyl-L-amino acid 12-hydroxylase
|
–
|
|
|
BRENDA:
BR52143
KEGG:
R11808
|
|
|
|
a_12-oxojasmonoyl-L-amino_acid + reduced_flavodoxin + O2 <=> a_12-hydroxy-12-oxojasmonoyl-L-amino_acid + flavin + H2O
|
1.14.14.49
12-hydroxyjasmonoyl-L-amino acid 12-hydroxylase
|
–
|
|
|
BRENDA:
BR52144
KEGG:
R11809
|
|
|
|
16-methoxytabersonine + reduced_flavodoxin + O2 <=> (3R)-3-hydroxy-16-methoxy-1,2-didehydro-2,3-dihydrotabersonine + flavin + H2O
|
1.14.14.50
tabersonine 3-oxygenase
|
–
|
K
|
|
BRENDA:
BR52145
KEGG:
R11810
|
|
|
|
tabersonine + reduced_flavodoxin + O2 <=> (3R)-3-hydroxy-1,2-didehydro-2,3-dihydrotabersonine + flavin + H2O
|
1.14.14.50
tabersonine 3-oxygenase
|
–
|
K
|
|
BRENDA:
BR52146
KEGG:
R11811
|
|
|
|
phenylacetate + reduced_flavodoxin + O2 <=> 2-hydroxyphenylacetate + flavin + H2O
|
1.14.14.54
phenylacetate 2-hydroxylase
|
–
|
K
|
|
BRENDA:
BR52147
KEGG:
R05487
|
|
|
|
2-(L-cystein-S-yl)-2-(1H-indol-3-yl)acetonitrile + 2 reduced_flavodoxin + 2 O2 <=> camalexin + cyanide + CO2 + 2 flavin + 4 H2O
|
1.14.19.52
camalexin synthase
|
–
|
|
|
BRENDA:
BR52149
KEGG:
R11813
|
|
|
|
2-(L-cystein-S-yl)-2-(1H-indol-3-yl)acetonitrile + reduced_flavodoxin + O2 <=> (R)-dihydrocamalexate + cyanide + flavin + 2 H2O
|
1.14.19.52
camalexin synthase
|
–
|
|
|
BRENDA:
BR52150
KEGG:
R11814
|
|
|
|
(R)-dihydrocamalexate + reduced_flavodoxin + O2 <=> camalexin + CO2 + flavin + 2 H2O
|
1.14.19.52
camalexin synthase
|
–
|
|
|
BRENDA:
BR52151
KEGG:
R11815
|
|
|
|
(L-prolyl)-[peptidyl-carrier_protein] + 2 flavin <=> (1H-pyrrole-2-carbonyl)-[peptidyl-carrier_protein] + 2 reduced_flavodoxin
|
1.3.8.14
L-prolyl-[peptidyl-carrier protein] dehydrogenase
|
–
|
K
|
|
BRENDA:
BR52237
KEGG:
R06747
|
|
|
|
(E,E)-geranyllinalool + reduced_flavodoxin + O2 <=> (E,E)-4,8,12-trimethyltrideca-1,3,7,11-tetraene + flavin + 3-buten-2-one + 2 H2O
|
1.14.14.58
trimethyltridecatetraene synthase
|
–
|
K
|
|
BRENDA:
BR52290
KEGG:
R10562
|
|
|
|
(3S,6E)-nerolidol + reduced_flavodoxin + O2 <=> (3E)-4,8-dimethylnona-1,3,7-triene + flavin + 3-buten-2-one + 2 H2O
|
1.14.14.58
trimethyltridecatetraene synthase
1.14.14.59
dimethylnonatriene synthase
|
–
–
|
|
|
BRENDA:
BR52291
KEGG:
R11949
|
|
|
|
ferruginol + reduced_flavodoxin + O2 <=> 11-hydroxyferruginol + flavin + H2O
|
1.14.14.60
ferruginol monooxygenase
|
–
|
K
|
|
BRENDA:
BR52292
KEGG:
R11951
|
|
|
|
11-hydroxyferruginol + 3 reduced_flavodoxin + 3 O2 <=> carnosic_acid + 3 flavin + 4 H2O
|
1.14.14.61
carnosic acid synthase
|
–
|
K
|
|
BRENDA:
BR52293
KEGG:
R11973
|
|
|
|
ferruginol + reduced_flavodoxin + O2 <=> salviol + flavin + H2O
|
1.14.14.62
salviol synthase
|
–
|
K
|
|
BRENDA:
BR52294
KEGG:
R11974
|
|
|
|
beta-amyrin + reduced_flavodoxin + O2 <=> maniladiol + flavin + H2O
|
1.14.14.63
beta-amyrin 16beta-monooxygenase
|
–
|
|
|
BRENDA:
BR52295
KEGG:
R11975
|
|
|
|
beta-amyrin + reduced_flavodoxin + O2 <=> daturadiol + flavin + H2O
|
1.14.14.64
beta-amyrin 6beta-monooxygenase
|
–
|
|
|
BRENDA:
BR52296
KEGG:
R11976
|
|
|
|
ferruginol + 2 reduced_flavodoxin + 2 O2 <=> sugiol + 2 flavin + 3 H2O
|
1.14.14.65
sugiol synthase
|
–
|
K
|
|
BRENDA:
BR52297
KEGG:
R11977
|
|
|
|
demethylsuberosin + reduced_flavodoxin + O2 <=> (+)-marmesin + flavin + H2O
|
1.14.14.66
marmesin synthase
|
–
|
|
|
BRENDA:
BR52298
KEGG:
R08997
|
|
|
|
11-hydroxysugiol + reduced_flavodoxin + O2 <=> 11,20-dihydroxysugiol + flavin + H2O
|
1.14.14.67
11-hydroxysugiol 20-monooxygenase
|
–
|
K
|
|
BRENDA:
BR52299
KEGG:
R11979
|
|
|
|
9beta-pimara-7,15-diene + reduced_flavodoxin + O2 <=> 9beta-pimara-7,15-diene-3beta-ol + flavin + H2O
|
1.14.14.68
syn-pimaradiene 3-monooxygenase
|
–
|
K
|
|
BRENDA:
BR52300
KEGG:
R11980
|
|
|
|
ent-cassa-12,15-diene + 3 reduced_flavodoxin + 3 O2 <=> ent-3beta-hydroxycassa-12,15-dien-2-one + 3 flavin + 4 H2O
|
1.14.14.69
ent-cassadiene hydroxylase
|
–
|
K
|
|
BRENDA:
BR52301
KEGG:
R11981
|
|
|
|
ent-cassa-12,15-diene + reduced_flavodoxin + O2 <=> 2alpha-hydroxy-ent-cassadiene + flavin + H2O
|
1.14.14.69
ent-cassadiene hydroxylase
|
–
|
|
|
BRENDA:
BR52302
KEGG:
R11982
|
|
|
|
2alpha-hydroxy-ent-cassadiene + reduced_flavodoxin + O2 <=> ent-cassa-12,15-dien-2-one + flavin + 2 H2O
|
1.14.14.69
ent-cassadiene hydroxylase
|
–
|
|
|
BRENDA:
BR52303
KEGG:
R11983
|
|
|
|
2alpha-hydroxy-ent-cassadiene + reduced_flavodoxin + O2 <=> ent-cassa-12,15-diene-2beta,3beta-diol + flavin + H2O
|
1.14.14.69
ent-cassadiene hydroxylase
|
–
|
|
|
BRENDA:
BR52304
KEGG:
R11985
|
|
|
|
ent-cassa-12,15-dien-2-one + reduced_flavodoxin + O2 <=> ent-3beta-hydroxycassa-12,15-dien-2-one + flavin + H2O
|
1.14.14.69
ent-cassadiene hydroxylase
|
–
|
|
|
BRENDA:
BR52305
KEGG:
R11984
|
|
|
|
ent-cassa-12,15-diene-2beta,3beta-diol + reduced_flavodoxin + O2 <=> ent-3beta-hydroxycassa-12,15-dien-2-one + flavin + 2 H2O
|
1.14.14.69
ent-cassadiene hydroxylase
|
–
|
|
|
BRENDA:
BR52306
KEGG:
R11986
|
|
|
|
cucurbitadienol + 2 reduced_flavodoxin + 2 O2 <=> 11-oxocucurbitadienol + 2 flavin + 3 H2O
|
1.14.14.71
cucurbitadienol 11-hydroxylase
|
–
|
|
|
BRENDA:
BR52346
KEGG:
R12007
|
|
|
|
cucurbitadienol + reduced_flavodoxin + O2 <=> 11-hydroxycucurbitadienol + flavin + H2O
|
1.14.14.71
cucurbitadienol 11-hydroxylase
|
–
|
|
|
BRENDA:
BR52347
KEGG:
R12008
|
|
|
|
11-hydroxycucurbitadienol + reduced_flavodoxin + O2 <=> 11-oxocucurbitadienol + flavin + 2 H2O
|
1.14.14.71
cucurbitadienol 11-hydroxylase
|
–
|
|
|
BRENDA:
BR52348
KEGG:
R12009
|
|
|
|
drimenol + reduced_flavodoxin + O2 <=> drimendiol + flavin + H2O
|
1.14.14.72
drimenol monooxygenase
|
–
|
|
|
BRENDA:
BR52349
KEGG:
R12010
|
|
|
|
(S)-reticuline + reduced_flavodoxin + O2 <=> 1,2-dehydroreticuline + flavin + 2 H2O
|
1.14.19.54
1,2-dehydroreticuline synthase
|
–
|
K
|
|
BRENDA:
BR52350
KEGG:
R03833
|
|
|
|
ent-kaur-16-ene + 3 reduced_flavodoxin + 3 O2 <=> ent-kaur-16-en-19-oate + 3 flavin + 4 H2O
|
1.14.14.86
ent-kaurene monooxygenase
|
–
|
|
|
BRENDA:
BR52392;
BS427442
KEGG:
R10066
|
|
|
|
a_flavanone + 2 reduced_flavodoxin + 2 O2 <=> a_3'',5''-dihydroxyflavanone + 2 flavin + 2 H2O
|
1.14.14.81
flavanoid 3',5'-hydroxylase
|
–
|
|
|
BRENDA:
BR52393
KEGG:
R10069
|
|
|
|
ent-isokaurene + O2 + reduced_flavodoxin <=> ent-isokauren-2beta-ol + flavin + H2O
|
1.14.14.76
ent-isokaurene C2/C3-hydroxylase
|
–
|
BK
|
|
BRENDA:
BR52394;
BS418604
KEGG:
R09861
|
|
|
|
ent-isokauren-2beta-ol + O2 + reduced_flavodoxin <=> ent-isokaurene-2beta,3beta-diol + flavin + H2O
|
1.14.14.76
ent-isokaurene C2/C3-hydroxylase
|
–
|
BK
|
|
BRENDA:
BR52395
KEGG:
R11978
|
|
|
|
albendazole + reduced_flavodoxin + O2 <=> albendazole_S-oxide + flavin + H2O
|
1.14.14.73
albendazole monooxygenase (sulfoxide-forming)
|
–
|
|
|
BRENDA:
BR52397
KEGG:
R12068
|
|
|
|
febendazole + reduced_flavodoxin + O2 <=> oxfendazole + flavin + H2O
|
1.14.14.73
albendazole monooxygenase (sulfoxide-forming)
|
–
|
|
|
BRENDA:
BR52398
KEGG:
R12069
|
|
|
|
albendazole + reduced_flavodoxin + O2 <=> hydroxyalbendazole + flavin + H2O
|
1.14.14.74
albendazole monooxygenase (hydroxylating)
|
–
|
|
|
BRENDA:
BR52399
KEGG:
R12070
|
|
|
|
febendazole + reduced_flavodoxin + O2 <=> 4''-hydroxyfenbendazole + flavin + H2O
|
1.14.14.75
fenbendazole monooxygenase (4'-hydroxylating)
|
–
|
|
|
BRENDA:
BR52400
KEGG:
R12071
|
|
|
|
a_14alpha-methylsteroid + reduced_flavodoxin + O2 <=> a_14alpha-hydroxymethylsteroid + flavin + H2O
|
1.14.14.154
sterol 14alpha-demethylase
|
–
|
|
|
BRENDA:
BR52435
KEGG:
R12119
|
|
|
|
a_14alpha-hydroxymethylsteroid + reduced_flavodoxin + O2 <=> a_14alpha-formylsteroid + flavin + 2 H2O
|
1.14.14.154
sterol 14alpha-demethylase
|
–
|
|
|
BRENDA:
BR52436
KEGG:
R12120
|
|
|
|
a_14alpha-formylsteroid + reduced_flavodoxin + O2 <=> a_DELTA14-steroid + formate + flavin + H2O
|
1.14.14.154
sterol 14alpha-demethylase
|
–
|
|
|
BRENDA:
BR52437
KEGG:
R12121
|
|
|
|
(6aS,11aS)-2-dimethylallyl-3,6a,9-trihydroxypterocarpan + reduced_flavodoxin + O2 <=> glyceollin_III + flavin + 2 H2O
|
1.14.14.135
glyceollin synthase
|
–
|
K
|
|
BRENDA:
BR52438
KEGG:
R07196
|
|
|
|
2-(or_4-)dimethylallyl-(6aS,11aS)-3,6a,9-trihydroxypterocarpan + reduced_flavodoxin + O2 <=> glyceollin + flavin + 2 H2O
|
1.14.14.135
glyceollin synthase
|
–
|
K
|
|
BRENDA:
BR52439
KEGG:
R07197;
R07357
|
|
|
|
abietadienal + reduced_flavodoxin + O2 <=> abietic_acid + flavin + H2O
|
1.14.14.145
abieta-7,13-dien-18-ol hydroxylase
|
–
|
K
|
|
BRENDA:
BR52440
KEGG:
R12123
|
|
|
|
germacra-1(10),4,11(13)-trien-12-oate + reduced_flavodoxin + O2 <=> 6alpha-hydroxygermacra-1(10),4,11(13)-trien-12-oate + flavin + H2O
|
1.14.14.150
costunolide synthase
|
–
|
B
|
|
BRENDA:
BR52441
KEGG:
R12131
|
|
|
|
(-)-vetispiradiene + 2 reduced_flavodoxin + 2 O2 <=> solavetivone + 2 flavin + 3 H2O
|
1.14.14.149
5-epiaristolochene 1,3-dihydroxylase
1.14.14.151
premnaspirodiene oxygenase
|
–
–
|
|
|
BRENDA:
BR52443;
BS413539
KEGG:
R10073
|
|
|
|
germacrene_A + O2 + reduced_flavodoxin <=> germacra-1(10),4,11(13)-trien-12-ol + flavin + H2O
|
1.14.14.95
germacrene A hydroxylase
|
–
|
BK
|
|
BRENDA:
BR52444
KEGG:
R09549
|
|
|
|
germacra-1(10),4,11(13)-trien-12-ol + O2 + reduced_flavodoxin <=> germacra-1(10),4,11(13)-trien-12-al + flavin + 2 H2O
|
1.14.14.95
germacrene A hydroxylase
|
–
|
B
|
|
BRENDA:
BR52445
KEGG:
R12129
|
|
|
|
germacra-1(10),4,11(13)-trien-12-al + O2 + reduced_flavodoxin <=> germacra-1(10),4,11(13)-trien-12-oate + flavin + H2O
|
1.14.14.95
germacrene A hydroxylase
|
–
|
B
|
|
BRENDA:
BR52446
KEGG:
R12130
|
|
|
|
zeinoxanthin + reduced_flavodoxin + O2 <=> lutein + flavin + H2O
|
1.14.14.158
carotenoid epsilon hydroxylase
|
–
|
BK
|
|
BRENDA:
BR52468
KEGG:
R07531
|
|
|
|
(+)-pinoresinol + reduced_flavodoxin + O2 <=> (+)-piperitol + flavin + 2 H2O
|
1.14.19.74
(+)-piperitol/(+)-sesamin synthase
|
–
|
|
|
BRENDA:
BR52469
KEGG:
R12153
|
|
|
|
(+)-piperitol + reduced_flavodoxin + O2 <=> sesamin + flavin + 2 H2O
|
1.14.19.74
(+)-piperitol/(+)-sesamin synthase
|
–
|
|
|
BRENDA:
BR52470
KEGG:
R12154
|
|
|
|
dolabradiene + O2 + reduced_flavodoxin <=> 15,16-epoxydolabrene + H2O + flavin
|
1.14.14.159
dolabradiene monooxygenase
|
–
|
|
|
BRENDA:
BR52513
KEGG:
R12224
|
|
|
|
15,16-epoxydolabrene + O2 + reduced_flavodoxin <=> 3beta-hydroxy-15,16-epoxydolabrene + H2O + flavin
|
1.14.14.159
dolabradiene monooxygenase
|
–
|
|
|
BRENDA:
BR52514
KEGG:
R12225
|
|
|
|
(S)-beta-macrocarpene + 3 O2 + 3 reduced_flavodoxin <=> zealexin_A1 + 4 H2O + 3 flavin
|
1.14.14.160
zealexin A1 synthase
|
–
|
|
|
BRENDA:
BR52515
KEGG:
R12226
|
|
|
|
(S)-beta-macrocarpene + O2 + reduced_flavodoxin <=> [(4S)-4-(5,5-dimethylcyclohex-1-en-1-yl)-cyclohex-1-en-1-yl]_methanol + H2O + flavin
|
1.14.14.160
zealexin A1 synthase
|
–
|
|
|
BRENDA:
BR52516
KEGG:
R12227
|
|
|
|
[(4S)-4-(5,5-dimethylcyclohex-1-en-1-yl)-cyclohex-1-en-1-yl]_methanol + O2 + reduced_flavodoxin <=> (4S)-4-(5,5-dimethylcyclohex-1-en-1-yl)cyclohex-1-ene-1-carbaldehyde + 2 H2O + flavin
|
1.14.14.160
zealexin A1 synthase
|
–
|
|
|
BRENDA:
BR52517
KEGG:
R12228
|
|
|
|
(4S)-4-(5,5-dimethylcyclohex-1-en-1-yl)cyclohex-1-ene-1-carbaldehyde + O2 + reduced_flavodoxin <=> zealexin_A1 + H2O + flavin
|
1.14.14.160
zealexin A1 synthase
|
–
|
|
|
BRENDA:
BR52518
KEGG:
R12229
|
|
|
|
cis-trans-nepetalactol + 3 reduced_flavodoxin + 3 O2 <=> 7-deoxyloganetate + 3 flavin + 4 H2O
|
1.14.14.161
nepetalactol monooxygenase
|
–
|
|
|
BRENDA:
BR52519
KEGG:
R12230
|
|
|
|
cis-trans-nepetalactol + reduced_flavodoxin + O2 <=> 7-deoxyloganetic_alcohol + flavin + H2O
|
1.14.14.161
nepetalactol monooxygenase
|
–
|
K
|
|
BRENDA:
BR52520
KEGG:
R12231
|
|
|
|
7-deoxyloganetic_alcohol + reduced_flavodoxin + O2 <=> iridotrial + flavin + 2 H2O
|
1.14.14.161
nepetalactol monooxygenase
|
–
|
K
|
|
BRENDA:
BR52521
KEGG:
R12253
|
|
|
|
iridotrial + reduced_flavodoxin + O2 <=> 7-deoxyloganetate + flavin + H2O
|
1.14.14.161
nepetalactol monooxygenase
|
–
|
K
|
|
BRENDA:
BR52522
KEGG:
R12182
|
|
|
|
a_flavanone + reduced_flavodoxin + O2 <=> a_2-hydroxyflavanone + flavin + H2O
|
1.14.14.162
flavanone 2-hydroxylase
|
–
|
|
|
BRENDA:
BR52524
KEGG:
R12218
|
|
|
|
(S)-1-hydroxy-N-methylcanadine + reduced_flavodoxin + O2 <=> (13S,14R)-1,13-dihydroxy-N-methylcanadine + flavin + H2O
|
1.14.14.163
(S)-1-hydroxy-N-methylcanadine 13-hydroxylase
|
–
|
K
|
|
BRENDA:
BR52525
KEGG:
R11688
|
|
|
|
fraxetin + reduced_flavodoxin + O2 <=> sideretin_(reduced_form) + flavin + H2O
|
1.14.14.164
fraxetin 5-hydroxylase
|
–
|
|
|
BRENDA:
BR52526
KEGG:
R12223
|
|
|
|
indole-3-carbonyl_nitrile + reduced_flavodoxin + O2 <=> 4-hydroxyindole-3-carbonyl_nitrile + flavin + H2O
|
1.14.14.165
indole-3-carbonyl nitrile 4-hydroxylase
|
–
|
|
|
BRENDA:
BR52527
KEGG:
R12232
|
|
|
|
(S)-N-methylcanadine + reduced_flavodoxin + O2 <=> (S)-1-hydroxy-N-methylcanadine + flavin + H2O
|
1.14.14.166
(S)-N-methylcanadine 1-hydroxylase
|
–
|
K
|
|
BRENDA:
BR52561
KEGG:
R11687
|
|
|
|
(13S,14R)-13-O-acetyl-1-hydroxy-N-methylcanadine + reduced_flavodoxin + O2 <=> (13S,14R)-13-O-acetyl-1,8-dihydroxy-N-methylcanadine + flavin + H2O
|
1.14.14.167
(13S,14R)-13-O-acetyl-1-hydroxy-N-methylcanadine 8-hydroxylase
|
–
|
K
|
|
BRENDA:
BR52562
KEGG:
R11690
|
|
|
|
germacra-1(10),4,11(13)-trien-12-oate + reduced_flavodoxin + O2 <=> 8beta-hydroxygermacra-1(10),4,11(13)-trien-12-oate + flavin + H2O
|
1.14.14.168
germacrene A acid 8beta-hydroxylase
|
–
|
B
|
|
BRENDA:
BR52563
KEGG:
R12266
|
|
|
|
8beta-hydroxygermacra-1(10),4,11(13)-trien-12-oate + reduced_flavodoxin + O2 <=> eupatolide + flavin + 2 H2O
|
1.14.14.169
eupatolide synthase
|
–
|
|
|
BRENDA:
BR52564
KEGG:
R12270
|
|
|
|
8beta-hydroxygermacra-1(10),4,11(13)-trien-12-oate + reduced_flavodoxin + O2 <=> 6alpha,8beta-dihydroxygermacra-1(10),4,11(13)-trien-12-oate + flavin + H2O
|
1.14.14.169
eupatolide synthase
|
–
|
B
|
|
BRENDA:
BR52565
KEGG:
R12267
|
|
|
|
germacra-1(10),4,11(13)-trien-12-oate + reduced_flavodoxin + O2 <=> 8-epi-inunolide + flavin + 2 H2O
|
1.14.14.170
8-epi-inunolide synthase
|
–
|
|
|
BRENDA:
BR52567
KEGG:
R12275
|
|
|
|
germacra-1(10),4,11(13)-trien-12-oate + reduced_flavodoxin + O2 <=> 8alpha-hydroxygermacra-1(10),4,11(13)-trien-12-oate + flavin + H2O
|
1.14.14.170
8-epi-inunolide synthase
|
–
|
B
|
|
BRENDA:
BR52568
KEGG:
R12273
|
|
|
|
a_flavanone + reduced_flavodoxin + O2 <=> a_flavone + flavin + 2 H2O
|
1.14.19.76
flavone synthase II
|
–
|
|
|
BRENDA:
BR52570
KEGG:
R12276
|
|
|
|
L-homomethionine + 2 reduced_flavodoxin + 2 O2 <=> an_omega-(methylthio)-(E)-alkanal_oxime + 2 flavin + CO2 + 3 H2O
|
1.14.14.42
homomethionine N-monooxygenase
|
–
|
K
|
|
BRENDA:
BR52625;
BS438376
KEGG:
R08665;
R11646
|
|
|
|
L-homomethionine + reduced_flavodoxin + O2 <=> an_L-N-hydroxypolyhomomethionine + flavin + H2O
|
1.14.14.42
homomethionine N-monooxygenase
|
–
|
|
|
BRENDA:
BR52626
KEGG:
R11647
|
|
|
|
an_L-N-hydroxypolyhomomethionine + reduced_flavodoxin + O2 <=> an_L-N,N-dihydroxypolyhomomethionine + flavin + H2O
|
1.14.14.42
homomethionine N-monooxygenase
|
–
|
|
|
BRENDA:
BR52627
KEGG:
R11648
|
|
|
|
beta-amyrin + reduced_flavodoxin + O2 <=> 16alpha-hydroxy-beta-amyrin + flavin + H2O
|
1.14.14.171
beta-amyrin 16alpha-hydroxylase
|
–
|
|
|
BRENDA:
BR52722
KEGG:
R12367
|
|
|
|
4-hydroxyphenylpropionic_acid + flavin <=> p-coumaric_acid + reduced_flavodoxin
|
1.3.8.15
3-(aryl)acrylate reductase
|
–
|
B
|
|
BRENDA:
BR52970
KEGG:
R12534
|
|
|
|
3-Phenylpropionic_acid + flavin <=> trans-cinnamate + reduced_flavodoxin
|
1.3.8.15
3-(aryl)acrylate reductase
|
–
|
B
|
|
BRENDA:
BR52971
KEGG:
R12535
|
|
|
|
Indole-3-propionic_acid + flavin <=> indole-3-acrylic_acid + reduced_flavodoxin
|
1.3.8.15
3-(aryl)acrylate reductase
|
–
|
B
|
|
BRENDA:
BR52972
KEGG:
R12536
|
|
|
|
protopine + reduced_flavodoxin + O2 <=> 6-hydroxyprotopine + flavin + H2O
|
1.14.14.98
protopine 6-monooxygenase
|
–
|
K
|
|
BRENDA:
BR652
KEGG:
R04699
|
|
|
|
Dihydrosanguinarine + reduced_flavodoxin + O2 <=> 10-Hydroxydihydrosanguinarine + flavin + H2O
|
1.14.14.100
dihydrosanguinarine 10-monooxygenase
|
–
|
K
|
|
BRENDA:
BR653
KEGG:
R04702
|
|
|
|
dihydrochelirubine + reduced_flavodoxin + O2 <=> 12-hydroxydihydrochelirubine + flavin + H2O
|
1.14.14.101
dihydrochelirubine 12-monooxygenase
|
–
|
K
|
|
BRENDA:
BR654
KEGG:
R04708
|
|
|
|
(S)-cis-N-Methylstylopine + reduced_flavodoxin + O2 <=> protopine + flavin + H2O
|
1.14.14.97
methyltetrahydroprotoberberine 14-monooxygenase
|
–
|
K
|
|
BRENDA:
BS186710
KEGG:
R04700
|
|
|
|
Biochanin_A + reduced_flavodoxin + O2 <=> Pratensein + flavin + H2O
|
1.14.14.88
isoflavone 3'-hydroxylase
|
–
|
K
|
|
BRENDA:
BS186715
KEGG:
R07776
|
|
|
|
Biochanin_A + reduced_flavodoxin + O2 <=> 2''-hydroxybiochanin_A + flavin + H2O
|
1.14.14.89
4'-methoxyisoflavone 2'-hydroxylase
1.14.14.90
isoflavone 2'-hydroxylase
|
–
–
|
K
|
|
BRENDA:
BS186718
KEGG:
R06561
|
|
|
|
daidzein + reduced_flavodoxin + O2 <=> 2''-hydroxydaidzein + flavin + H2O
|
1.14.14.89
4'-methoxyisoflavone 2'-hydroxylase
1.14.14.90
isoflavone 2'-hydroxylase
|
–
–
|
K
|
|
BRENDA:
BS186719
KEGG:
R06606
|
|
|
|
genistein + reduced_flavodoxin + O2 <=> 2''-hydroxygenistein + flavin + H2O
|
1.14.14.89
4'-methoxyisoflavone 2'-hydroxylase
1.14.14.90
isoflavone 2'-hydroxylase
|
–
–
|
K
|
|
BRENDA:
BS186720
KEGG:
R06607
|
|
|
|
obtusifoliol + reduced_flavodoxin + O2 <=> 4alpha-methyl-5alpha-ergosta-8,14,24(28)-trien-3beta-ol + formate + flavin + H2O
|
1.14.14.154
sterol 14alpha-demethylase
|
–
|
K
|
|
BRENDA:
BS186733
KEGG:
R05731
|
|
|
|
lanosterol + reduced_flavodoxin + O2 <=> 4,4-dimethyl-5alpha-cholesta-8,14,24-trien-3beta-ol + formate + flavin + H2O
|
1.14.14.154
sterol 14alpha-demethylase
|
–
|
BK
|
|
BRENDA:
BS186735
KEGG:
R05640
|
|
|
|
progesterone + reduced_flavodoxin + O2 <=> 17alpha-hydroxyprogesterone + flavin + H2O
|
1.14.14.19
steroid 17alpha-monooxygenase
1.14.14.32
17alpha-hydroxyprogesterone deacetylase
|
–
–
|
K
|
|
BRENDA:
BS258003
KEGG:
R02211
|
|
|
|
4-coumaroylshikimate + reduced_flavodoxin + O2 <=> trans-5-O-caffeoylshikimate + flavin + H2O
|
1.14.14.96
5-O-(4-coumaroyl)-D-quinate 3'-monooxygenase
|
–
|
K
|
|
BRENDA:
BS260915
KEGG:
R06582
|
|
|
|
naringenin + reduced_flavodoxin + O2 <=> eriodictyol + flavin + H2O
|
1.14.14.81
flavanoid 3',5'-hydroxylase
1.14.14.82
flavonoid 3'-monooxygenase
|
–
–
|
K
|
|
BRENDA:
BS288543;
BS372123
KEGG:
R02442
|
|
|
|
dihydrokaempferol + reduced_flavodoxin + O2 <=> dihydroquercetin + flavin + H2O
|
1.14.14.81
flavanoid 3',5'-hydroxylase
1.14.14.82
flavonoid 3'-monooxygenase
|
–
–
|
K
|
|
BRENDA:
BS288544
KEGG:
R03124
|
|
|
|
apigenin + reduced_flavodoxin + O2 <=> luteolin + flavin + H2O
|
1.14.14.81
flavanoid 3',5'-hydroxylase
1.14.14.82
flavonoid 3'-monooxygenase
|
–
–
|
K
|
|
BRENDA:
BS288545
KEGG:
R06537
|
|
|
|
kaempferol + reduced_flavodoxin + O2 <=> quercetin + flavin + H2O
|
1.14.14.81
flavanoid 3',5'-hydroxylase
1.14.14.82
flavonoid 3'-monooxygenase
|
–
–
|
K
|
|
BRENDA:
BS288546
KEGG:
R06538
|
|
|
|
7-deoxyloganin + reduced_flavodoxin + O2 <=> loganin + flavin + H2O
|
1.14.14.85
7-deoxyloganate 7-hydroxylase
|
–
|
K
|
|
BRENDA:
BS289300
KEGG:
R03556
|
|
|
|
acyl-CoA + flavin <=> trans-2-enoyl-CoA + reduced_flavodoxin
|
1.3.8.7
medium-chain acyl-CoA dehydrogenase
1.3.8.8
long-chain acyl-CoA dehydrogenase
|
–
–
|
|
|
BRENDA:
BS370165
KEGG:
R00392
|
|
|
|
liquiritigenin + reduced_flavodoxin + O2 <=> licodione + flavin + H2O
|
1.14.14.162
flavanone 2-hydroxylase
|
–
|
|
|
BRENDA:
BS371262
KEGG:
R07198
|
|
|
|
naringenin + 2 reduced_flavodoxin + 2 O2 <=> (2S)-5,7,3'',4'',5''-pentahydroxyflavanone + 2 flavin + 2 H2O
|
1.14.14.81
flavanoid 3',5'-hydroxylase
|
–
|
|
|
BRENDA:
BS372122
KEGG:
R02443
|
|
|
|
eriodictyol + reduced_flavodoxin + O2 <=> luteolin + flavin + H2O
|
1.14.14.162
flavanone 2-hydroxylase
1.14.19.76
flavone synthase II
|
–
–
|
K
|
|
BRENDA:
BS373155
KEGG:
R12279
|
|
|
|
arachidonic_acid + reduced_flavodoxin + O2 <=> 20-hydroxyeicosatetraenoic_acid + flavin + H2O
|
1.14.14.78
phylloquinone omega-hydroxylase
1.14.14.79
docosahexaenoic acid omega-hydroxylase
1.14.14.80
long-chain fatty acid omega-monooxygenase
1.14.14.94
leukotriene-B4 20-monooxygenase
|
–
–
–
–
|
K
|
|
BRENDA:
BS375050
KEGG:
R07041
|
|
|
|
dihydrokaempferol + 2 reduced_flavodoxin + 2 O2 <=> dihydromyricetin + 2 flavin + 2 H2O
|
1.14.14.81
flavanoid 3',5'-hydroxylase
|
–
|
|
|
BRENDA:
BS386445
KEGG:
R03125
|
|
|
|
abietadienol + reduced_flavodoxin + O2 <=> abietadienal + flavin + H2O
|
1.14.14.145
abieta-7,13-dien-18-ol hydroxylase
|
–
|
K
|
|
BRENDA:
BS387688
KEGG:
R06354
|
|
|
|
kaempferol + 2 reduced_flavodoxin + 2 O2 <=> 5,7,3'',4'',5''-pentahydroxyflavone + 2 flavin + 2 H2O
|
1.14.14.81
flavanoid 3',5'-hydroxylase
|
–
|
K
|
|
BRENDA:
BS388957
KEGG:
R10260
|
|
|
|
(22S)-22-hydroxycampest-4-en-3-one + reduced_flavodoxin + O2 <=> (22R,23R)-22,23-dihydroxycampest-4-en-3-one + flavin + H2O
|
1.14.14.147
3-epi-6-deoxocathasterone 23-monooxygenase
|
–
|
K
|
|
BRENDA:
BS399135
KEGG:
R07787
|
|
|
|
(22S)-22-hydroxycampesterol + reduced_flavodoxin + O2 <=> (22R,23R)-22,23-dihydroxycampesterol + flavin + H2O
|
1.14.14.147
3-epi-6-deoxocathasterone 23-monooxygenase
|
–
|
K
|
|
BRENDA:
BS399136
KEGG:
R07786
|
|
|
|
palmitate + reduced_flavodoxin + O2 <=> 16-hydroxypalmitic_acid + flavin + H2O
|
1.14
1.14.14.78
phylloquinone omega-hydroxylase
1.14.14.80
long-chain fatty acid omega-monooxygenase
|
–
–
–
|
K
|
|
BRENDA:
BS410038
KEGG:
R09451
|
|
|
|
germacra-1(10),4,11(13)-trien-12-ol + 2 O2 + 2 reduced_flavodoxin <=> germacra-1(10),4,11(13)-trien-12-oate + 2 flavin + 3 H2O
|
1.14.14.95
germacrene A hydroxylase
|
–
|
K
|
|
BRENDA:
BS417032
KEGG:
R09548
|
|
|
|
2-hydroxy-2H-1,4-benzoxazin-3(4H)-one + reduced_flavodoxin + O2 <=> 2,4-dihydroxy-2H-1,4-benzoxazin-3(4H)-one + flavin + H2O
|
1.14.14.110
2-hydroxy-1,4-benzoxazin-3-one monooxygenase
|
–
|
K
|
|
BRENDA:
BS422405
KEGG:
R07423
|
|
|
|
17alpha-hydroxyprogesterone + reduced_flavodoxin + O2 <=> 11-deoxycortisol + flavin + H2O
|
1.14.14.16
steroid 21-monooxygenase
|
–
|
K
|
|
BRENDA:
BS427270
KEGG:
R03326
|
|
|
|
pregnenolone + reduced_flavodoxin + O2 <=> 17alpha-hydroxypregnenolone + flavin + H2O
|
1.14.14.19
steroid 17alpha-monooxygenase
1.14.14.32
17alpha-hydroxyprogesterone deacetylase
|
–
–
|
K
|
|
BRENDA:
BS427508
KEGG:
R03783
|
|
|
|
progesterone + reduced_flavodoxin + O2 <=> 11-deoxycorticosterone + flavin + H2O
|
1.14.14.16
steroid 21-monooxygenase
|
–
|
K
|
|
BRENDA:
BS427511
KEGG:
R02213
|
|
|
|
oleic_acid + reduced_flavodoxin + O2 <=> omega-hydroxy_oleic_acid + flavin + H2O
|
1.14.14.129
long-chain acyl-CoA omega-monooxygenase
1.14.14.78
phylloquinone omega-hydroxylase
1.14.14.80
long-chain fatty acid omega-monooxygenase
|
–
–
–
|
K
|
|
BRENDA:
BS430577
KEGG:
R09452
|
|
|
|
(E,Z)-indolyl-3-acetaldoxime + reduced_flavodoxin + O2 <=> 1-aci-nitro-2-indolyl-ethane + flavin + 2 H2O
|
1.14.14.45
aromatic aldoxime N-monooxygenase
|
–
|
|
|
BRENDA:
BS438363
KEGG:
R11735
|
|
|
|
L-dihomomethionine + 2 O2 + 2 reduced_flavodoxin <=> omega-(methylthio)-(E)-alkanal_oxime + CO2 + 3 H2O + 2 flavin
|
1.14.14.42
homomethionine N-monooxygenase
|
–
|
K
|
|
BRENDA:
BS438372
KEGG:
R08670
|
|
|
|
L-hexahomomethionine + 2 O2 + 2 reduced_flavodoxin <=> 4-methylthiononanaldoxime + CO2 + 3 H2O + 2 flavin
|
1.14.14.42
homomethionine N-monooxygenase
|
–
|
K
|
|
BRENDA:
BS438375
KEGG:
R08675
|
|
|
|
L-pentahomomethionine + 2 O2 + 2 reduced_flavodoxin <=> 4-methylthiooctanaldoxime + CO2 + 3 H2O + 2 flavin
|
1.14.14.42
homomethionine N-monooxygenase
|
–
|
K
|
|
BRENDA:
BS438382
KEGG:
R08674
|
|
|
|
L-tetrahomomethionine + 2 O2 + 2 reduced_flavodoxin <=> 4-methylthioheptanaldoxime + CO2 + 3 H2O + 2 flavin
|
1.14.14.42
homomethionine N-monooxygenase
|
–
|
K
|
|
BRENDA:
BS438386
KEGG:
R08673
|
|
|
|
dihydroquercetin + reduced_flavodoxin + O2 <=> dihydromyricetin + flavin + H2O
|
1.14.14.81
flavanoid 3',5'-hydroxylase
|
–
|
K
|
|
BRENDA:
BS442378
KEGG:
R03639
|
|
|
|
fatty_acid + reduced_flavodoxin + O2 <=> omega-hydroxy_fatty_acid + flavin + H2O
|
1.14.14.80
long-chain fatty acid omega-monooxygenase
|
–
|
K
|
|
BRENDA:
BS442561
KEGG:
R01348
|
|
|
|
11-hydroxyferruginol + reduced_flavodoxin + O2 <=> 11,20-dihydroxyferruginol + flavin + H2O
|
1.14.14.67
11-hydroxysugiol 20-monooxygenase
|
–
|
K
|
|
BRENDA:
BS442718
KEGG:
R11987
|
|
|
|
11-hydroxyferruginol + reduced_flavodoxin + O2 <=> 11-hydroxysugiol + flavin + H2O
|
1.14.14.65
sugiol synthase
|
–
|
K
|
|
BRENDA:
BS442719
KEGG:
R11990
|
|
|
|
ferruginol + 3 reduced_flavodoxin + 3 O2 <=> pisiferic_acid + 3 flavin + 4 H2O
|
1.14.14.61
carnosic acid synthase
|
–
|
K
|
|
BRENDA:
BS443561
KEGG:
R11989
|
|
|
|
sugiol + reduced_flavodoxin + O2 <=> 11-hydroxysugiol + flavin + H2O
|
1.14.14.60
ferruginol monooxygenase
|
–
|
K
|
|
BRENDA:
BS443912
KEGG:
R11988
|
|
|
|
liquiritigenin + reduced_flavodoxin + O2 <=> 7,4''-dihydroxyflavone + flavin + 2 H2O
|
1.14.19.76
flavone synthase II
|
–
|
K
|
|
BRENDA:
BS446301
KEGG:
R12277
|
|
|
|
naringenin + reduced_flavodoxin + O2 <=> apigenin + flavin + 2 H2O
|
1.14.19.76
flavone synthase II
|
–
|
K
|
|
BRENDA:
BS446316
KEGG:
R12278
|
|
|
|
pyruvate + CoA + flavin + H+ <=> acetyl-CoA + CO2 + reduced_flavodoxin
|
1.2.7
1.2.7.1
pyruvate synthase
|
–
–
|
K
|
|
KEGG:
R10866
MetaCyc:
PYFLAVOXRE-RXN
|
|
|
|
1,8-cineole + reduced_flavodoxin + O2 <=> 6-endo-hydroxycineole + flavin + H2O
|
1.14.14.133
1,8-cineole 2-endo-monooxygenase
|
–
|
K
|
|
KEGG:
R08784
MetaCyc:
RXN-13136
|
|
|
|
4-androstene-3,17-dione + reduced_flavodoxin + O2 <=> 7alpha-hydroxy-4-androstene-3,17-dione + flavin + H2O
|
1.14.14.1
unspecific monooxygenase
|
–
|
K
|
|
KEGG:
R01842
|
|
|
|
steroid + reduced_flavodoxin + O2 <=> 21-Hydroxysteroid + flavin + H2O
|
1.14.14.16
steroid 21-monooxygenase
|
–
|
|
|
KEGG:
R02130
|
|
|
|
steroid + reduced_flavodoxin + O2 <=> 5alpha-androstane-3alpha,17beta-diol + flavin + H2O
|
1.14.14.19
steroid 17alpha-monooxygenase
|
–
|
|
|
KEGG:
R02131
|
|
|
|
testosterone + reduced_flavodoxin + O2 <=> 7alpha,17beta-dihydroxyandrost-4-en-3-one + flavin + H2O
|
1.14.14.1
unspecific monooxygenase
|
–
|
K
|
|
KEGG:
R02503
|
|
|
|
21-deoxycortisol + reduced_flavodoxin + O2 <=> cortisol + flavin + H2O
|
1.14.14.16
steroid 21-monooxygenase
|
–
|
K
|
|
KEGG:
R02838
|
|
|
|
Melatonin + reduced_flavodoxin + O2 <=> 6-hydroxymelatonin + flavin + H2O
|
1.14.14.1
unspecific monooxygenase
|
–
|
K
|
|
KEGG:
R03629
|
|
|
|
morphine + flavin + formaldehyde + H2O <=> codeine + reduced_flavodoxin + O2
|
1.14.14.1
unspecific monooxygenase
|
–
|
K
|
|
KEGG:
R03697
|
|
|
|
pregnenolone + reduced_flavodoxin + O2 <=> 21-hydroxypregnenolone + flavin + H2O
|
1.14.14.16
steroid 21-monooxygenase
|
–
|
K
|
|
KEGG:
R03784
|
|
|
|
11beta-hydroxyprogesterone + reduced_flavodoxin + O2 <=> corticosterone + flavin + H2O
|
1.14.14.16
steroid 21-monooxygenase
|
–
|
K
|
|
KEGG:
R03849
|
|
|
|
reduced_flavodoxin + fatty_acid + O2 <=> alpha-Hydroxy_fatty_acid + flavin + H2O
|
1.14.14.1
unspecific monooxygenase
|
–
|
K
|
|
KEGG:
R04121
|
|
|
|
flavin + propionyl-CoA <=> reduced_flavodoxin + acryloyl-CoA
|
1.3.8.1
short-chain acyl-CoA dehydrogenase
|
–
|
K
|
|
KEGG:
R04432
|
|
|
|
17alpha-hydroxypregnenolone + reduced_flavodoxin + O2 <=> 17alpha,21-Dihydroxypregnenolone + flavin + H2O
|
1.14.14.16
steroid 21-monooxygenase
|
–
|
K
|
|
KEGG:
R04675
|
|
|
|
S-adenosyl-L-methionine + reduced_flavodoxin + Protein_glycine <=> 5''-Deoxyadenosine + L-methionine + reduced_flavodoxin + Protein_glycin-2-yl_radical
|
1.97.1.4
[formate-C-acetyltransferase]-activating enzyme
|
–
|
|
|
KEGG:
R04710
|
|
|
|
21-deoxycortisol + flavin + H2O <=> 11beta-hydroxyprogesterone + reduced_flavodoxin + O2
|
1.14.14.19
steroid 17alpha-monooxygenase
|
–
|
K
|
|
KEGG:
R04852
|
|
|
|
20alpha-hydroxycholesterol + reduced_flavodoxin + O2 <=> 17alpha,20alpha-dihydroxycholesterol + flavin + H2O
|
1.14.14.19
steroid 17alpha-monooxygenase
|
–
|
K
|
|
KEGG:
R04853
|
|
|
|
eriodictyol + reduced_flavodoxin + O2 <=> pentahydroxyflavanone + flavin + H2O
|
1.14.14.81
flavanoid 3',5'-hydroxylase
|
–
|
K
|
|
KEGG:
R04902
|
|
|
|
(S)-Coclaurine + (R)-N-methylcoclaurine + reduced_flavodoxin + O2 <=> 2''-Norberbamunine + flavin + 2 H2O
|
1.14.19.66
berbamunine synthase
|
–
|
K
|
|
KEGG:
R05210
|
|
|
|
2 (R)-N-methylcoclaurine + reduced_flavodoxin + O2 <=> (R,R)-guattegaumerine + flavin + 2 H2O
|
1.14.19.66
berbamunine synthase
|
–
|
K
|
|
KEGG:
R05215
|
|
|
|
parathion + reduced_flavodoxin + O2 <=> paraoxon + flavin + sulfur + H2O
|
1.14.14.1
unspecific monooxygenase
|
–
|
K
|
|
KEGG:
R05259
|
|
|
|
Geissoschizine + reduced_flavodoxin + O2 <=> polyneuridine_aldehyde + flavin + 2 H2O
|
1.14.14
|
–
|
K
|
|
KEGG:
R05829
|
|
|
|
loganic_acid + reduced_flavodoxin + O2 <=> secologanate + flavin + 2 H2O
|
1.14.19.62
secologanin synthase
|
–
|
K
|
|
KEGG:
R05833
|
|
|
|
Ajmalicine + reduced_flavodoxin + O2 <=> serpentine + flavin + 2 H2O + 2 H+
|
1.14.14
|
–
|
K
|
|
KEGG:
R05849
|
|
|
|
ent-7alpha-hydroxykaur-16-en-19-oate + reduced_flavodoxin + O2 <=> 6beta,7beta-Dihydroxykaurenoic_acid + flavin + H2O
|
1.14.14.107
ent-kaurenoic acid monooxygenase
|
–
|
K
|
|
KEGG:
R06296
|
|
|
|
taxa-4(20),11-dien-5alpha-ol + reduced_flavodoxin + O2 <=> taxa-4(20),11-dien-5alpha,13alpha-diol + flavin + H2O
|
1.14.14.106
taxane 13alpha-hydroxylase
|
–
|
K
|
|
KEGG:
R06308
|
|
|
|
arachidonic_acid + reduced_flavodoxin + O2 <=> 19(S)-HETE + flavin + H2O
|
1.14.13
1.14.14
1.14.14.1
unspecific monooxygenase
1.14.14.80
long-chain fatty acid omega-monooxygenase
|
–
–
–
–
|
K
|
|
KEGG:
R07046
|
|
|
|
(6aS,11aS)-2-dimethylallyl-3,6a,9-trihydroxypterocarpan + reduced_flavodoxin + O2 <=> glyceollin + flavin + 2 H2O
|
1.14.14.135
glyceollin synthase
|
–
|
|
|
KEGG:
R07356
|
|
|
|
27-Hydroxycholesterol + reduced_flavodoxin + O2 <=> 7alpha,27-dihydroxycholesterol + flavin + H2O
|
1.14.14.23
cholesterol 7alpha-monooxygenase
1.14.14.29
25/26-hydroxycholesterol 7alpha-hydroxylase
|
–
–
|
K
|
|
KEGG:
R07372
|
|
|
|
6-Deoxocastasterone + O2 + reduced_flavodoxin <=> 6alpha-Hydroxy-castasterone + H2O + flavin
|
1.14
|
–
|
K
|
|
KEGG:
R07450
|
|
|
|
6alpha-Hydroxy-castasterone + O2 + reduced_flavodoxin <=> 24-epicastasterone + 2 H2O + flavin
|
1.14
|
–
|
K
|
|
KEGG:
R07451
|
|
|
|
6-deoxoteasterone + 2 O2 + 2 reduced_flavodoxin <=> Teasterone + 3 H2O + 2 flavin
|
1.14
|
–
|
K
|
|
KEGG:
R07455
|
|
|
|
3-dehydro-6-deoxoteasterone + 2 O2 + 2 reduced_flavodoxin <=> 3-Dehydroteasterone + 3 H2O + 2 flavin
|
1.14
|
–
|
K
|
|
KEGG:
R07457
|
|
|
|
6-deoxotyphasterol + 2 O2 + 2 reduced_flavodoxin <=> typhasterol + 3 H2O + 2 flavin
|
1.14
|
–
|
K
|
|
KEGG:
R07458
|
|
|
|
6,7,4''-Trihydroxyflavanone + O2 + reduced_flavodoxin <=> 2,6,7,4''-Tetrahydroxyisoflavanone + H2O + flavin
|
1.14.14.87
2-hydroxyisoflavanone synthase
|
–
|
K
|
|
KEGG:
R07715
|
|
|
|
pseudobaptigenin + reduced_flavodoxin + O2 <=> 2'',7-Dihydroxy-4'',5''-methylenedioxyisoflavone + flavin + H2O
|
1.14.14.90
isoflavone 2'-hydroxylase
|
–
|
K
|
|
KEGG:
R07746
|
|
|
|
liquiritigenin + reduced_flavodoxin + O2 <=> butin + flavin + H2O
|
1.14.14.82
flavonoid 3'-monooxygenase
|
–
|
K
|
|
KEGG:
R08002
|
|
|
|
3,7,4'-trihydroxyflavanone + reduced_flavodoxin + O2 <=> fustin + flavin + H2O
|
1.14.14.82
flavonoid 3'-monooxygenase
|
–
|
K
|
|
KEGG:
R08032
|
|
|
|
Isopentenyladenosine-5''-triphosphate + reduced_flavodoxin + O2 <=> N6-(4-hydroxy-3-methyl-2-(E)-butenyl)ATP + flavin + H2O
|
not assigned
|
–
|
K
|
|
KEGG:
R08053
|
|
|
|
Isopentenyladenosine-5''-diphosphate + reduced_flavodoxin + O2 <=> N6-(4-hydroxy-3-methyl-2-(E)-butenyl)ADP + flavin + H2O
|
not assigned
|
–
|
K
|
|
KEGG:
R08054
|
|
|
|
N6-(delta2-Isopentenyl)-adenosine_5''-monophosphate + reduced_flavodoxin + O2 <=> N6-(4-hydroxy-3-methyl-2-(E)-butyl)adenosine_5'-phosphate + flavin + H2O
|
not assigned
|
–
|
K
|
|
KEGG:
R08055
|
|
|
|
N6-isopentenyladenosine + reduced_flavodoxin + O2 <=> zeatin_riboside + flavin + H2O
|
not assigned
|
–
|
K
|
|
KEGG:
R08066
|
|
|
|
N6-(2-isopentenyl)adenine + reduced_flavodoxin + O2 <=> trans-zeatin + flavin + H2O
|
not assigned
|
–
|
K
|
|
KEGG:
R08068
|
|
|
|
Tegafur + reduced_flavodoxin + O2 <=> 5-fluorouracil + 1,4-butanedione + flavin + H2O
|
1.14.14.1
unspecific monooxygenase
|
–
|
K
|
|
KEGG:
R08225
|
|
|
|
irinotecan + 2 reduced_flavodoxin + 2 O2 <=> NPC + Glutaraldehyde + 2 flavin + 2 H2O
|
1.14.13
|
–
|
K
|
|
KEGG:
R08257
|
|
|
|
codeine + reduced_flavodoxin + O2 <=> Norcodeine + formaldehyde + flavin + H2O
|
1.14.13
|
–
|
K
|
|
KEGG:
R08264
|
|
|
|
morphine + reduced_flavodoxin + O2 <=> normorphine + formaldehyde + flavin + H2O
|
1.14.14.1
unspecific monooxygenase
|
–
|
K
|
|
KEGG:
R08265
|
|
|
|
retinoic_acid + reduced_flavodoxin + O2 <=> all-trans-18-Hydroxyretinoic_acid + flavin + H2O
|
1.14.13
1.14.14
1.14.14.1
unspecific monooxygenase
|
–
–
–
|
K
|
|
KEGG:
R08390
|
|
|
|
4''-O-Methylnorbelladine + reduced_flavodoxin + O2 <=> N-Demethylnarwedine + flavin + 2 H2O
|
1.14.19
|
–
|
K
|
|
KEGG:
R08440
|
|
|
|
L-phenylalanine + 2 O2 + 2 reduced_flavodoxin <=> (Z)-phenylacetaldoxime + 2 flavin + CO2 + 3 H2O
|
1.14.14.40
phenylalanine N-monooxygenase
|
–
|
|
|
KEGG:
R08652
|
|
|
|
4-methylthiobutanaldoxime + L-cysteine + reduced_flavodoxin + O2 <=> S-(4-Methylthiobutylthiohydroximoyl)-L-cysteine + flavin + 2 H2O
|
1.14.14.43
(methylsulfanyl)alkanaldoxime N-monooxygenase
|
–
|
K
|
|
KEGG:
R08666
|
|
|
|
L-trihomomethionine + 2 reduced_flavodoxin + 2 O2 <=> 6-Methylthiohexanaldoxime + 2 flavin + CO2 + 3 H2O
|
1.14.14.42
homomethionine N-monooxygenase
|
–
|
K
|
|
KEGG:
R08672
|
|
|
|
cinnamoyl-CoA + reduced_flavodoxin + O2 <=> 4-coumaroyl-CoA + flavin + H2O
|
1.14.14.91
trans-cinnamate 4-monooxygenase
|
–
|
K
|
|
KEGG:
R08815
|
|
|
|
Teasterone + reduced_flavodoxin + O2 <=> 7-Oxateasterone + flavin + H2O
|
1.14.14
|
–
|
K
|
|
KEGG:
R08840
|
|
|
|
typhasterol + reduced_flavodoxin + O2 <=> 7-Oxatyphasterol + flavin + H2O
|
1.14.14
|
–
|
K
|
|
KEGG:
R08841
|
|
|
|
dehydroepiandrosterone + O2 + reduced_flavodoxin <=> 7alpha-hydroxydehydroepiandrosterone + flavin + H2O
|
1.14.14.23
cholesterol 7alpha-monooxygenase
|
–
|
K
|
|
KEGG:
R08961
|
|
|
|
stemod-13(17)-ene + 3 O2 + 3 reduced_flavodoxin <=> syn-stemoden-19-oate + 3 flavin + 4 H2O
|
1.14.14.111
9beta-pimara-7,15-diene oxidase
|
–
|
K
|
|
KEGG:
R09921
|
|
|
|
(3S)-linalool + reduced_flavodoxin + O2 <=> (6E)-8-hydroxylinalool + flavin + H2O
|
1.14.14.84
linalool 8-monooxygenase
|
–
|
K
|
|
KEGG:
R09922
|
|
|
|
quercetin + reduced_flavodoxin + O2 <=> myricetin + flavin + H2O
|
1.14.14.81
flavanoid 3',5'-hydroxylase
|
–
|
K
|
|
KEGG:
R10258
|
|
|
|
6-Deoxocastasterone + 2 O2 + 2 reduced_flavodoxin <=> 24-epicastasterone + 3 H2O + 2 flavin
|
1.14
|
–
|
|
|
KEGG:
R10669
|
|
|
|
6-Deoxocastasterone + 3 O2 + 3 reduced_flavodoxin <=> 24-epibrassinolide + 4 H2O + 3 flavin
|
1.14
|
–
|
|
|
KEGG:
R10682
|
|
|
|
6-deoxotyphasterol + 3 O2 + 3 reduced_flavodoxin <=> 7-Oxatyphasterol + 4 H2O + 3 flavin
|
1.14
|
–
|
|
|
KEGG:
R10683
|
|
|
|
6-deoxoteasterone + 3 O2 + 3 reduced_flavodoxin <=> 7-Oxateasterone + 4 H2O + 3 flavin
|
1.14
|
–
|
|
|
KEGG:
R10684
|
|
|
|
(E,Z)-indolyl-3-acetaldoxime + reduced_flavodoxin + glutathione + O2 <=> S-[(E)-N-hydroxy(indol-3-yl)acetimidoyl]-L-glutathione + flavin + 2 H2O
|
1.14.14.45
aromatic aldoxime N-monooxygenase
|
–
|
|
|
KEGG:
R11734
|
|
|
|
cis-trans-nepetalactol + 2 reduced_flavodoxin + 2 O2 <=> iridotrial + 2 flavin + 3 H2O
|
1.14.14.161
nepetalactol monooxygenase
|
–
|
|
|
KEGG:
R12181
|
|
|
|
Tetrahydroalstonine + reduced_flavodoxin + O2 <=> Alstonine + flavin + 2 H2O + 2 H+
|
1.14.14
|
–
|
K
|
|
KEGG:
R12282
|
|
|
|
guaiacol + reduced_flavodoxin + O2 <=> catechol + flavin + formaldehyde + H2O
|
1.14.14
|
–
|
K
|
|
KEGG:
R12301
|
|
|
|
Fumiquinazoline_F + 3 reduced_flavodoxin + 2 O2 <=> Fumiquinazoline_F-indoline-2'',3''-diol + 3 flavin + 2 H2O
|
1.14.14
|
–
|
K
|
|
KEGG:
R12418
|
|
|
|
Roquefortine_C + 2 reduced_flavodoxin + 2 O2 <=> Glandicoline_A + 2 flavin + 3 H2O
|
1.14.14
|
–
|
K
|
|
KEGG:
R12441
|
|
|
|
Glandicoline_A + reduced_flavodoxin + O2 <=> Glandicoline_B + flavin + H2O
|
1.14.14
|
–
|
K
|
|
KEGG:
R12442
|
|
|
|
Roquefortine_C + reduced_flavodoxin + O2 <=> N1-Hydroxy-roquefortine_C + flavin + H2O
|
1.14.14
|
–
|
K
|
|
KEGG:
R12444
|
|
|
|
N1-Hydroxy-roquefortine_C + reduced_flavodoxin + O2 <=> Roquefortine_L + flavin + 2 H2O
|
1.14.14
|
–
|
K
|
|
KEGG:
R12445
|
|
|
|
Roquefortine_L + reduced_flavodoxin + O2 <=> Glandicoline_B + flavin + H2O
|
1.14.14
|
–
|
K
|
|
KEGG:
R12446
|
|
|
|
Roquefortine_F + reduced_flavodoxin + O2 <=> Neoxaline + flavin + H2O
|
1.14.14
|
–
|
K
|
|
KEGG:
R12448
|
|
|
|
reduced_flavodoxin + ubiquinone-6 <=> oxidized_electron_transfer_flavoprotein + ubiquinol-6 + H+
|
1.5.5.1
electron-transferring-flavoprotein dehydrogenase
|
–
|
|
|
MetaCyc:
1.5.5.1-RXN-YEAST
|
|
|
|
Dimethylamine + H2O + oxidized_electron_transfer_flavoprotein + H+ <=> formaldehyde + methylamine + reduced_flavodoxin
|
1.5.8.1
dimethylamine dehydrogenase
|
–
|
|
|
MetaCyc:
1.5.8.1-RXN
|
|
|
|
(S)-2-methylbutanoyl-CoA + oxidized_electron_transfer_flavoprotein + H+ <=> tigloyl-CoA + reduced_flavodoxin
|
1.3.8.5
2-methyl-branched-chain-enoyl-CoA reductase
|
–
|
M
|
|
MetaCyc:
2-METHYLACYL-COA-DEHYDROGENASE-RXN
|
|
|
|
2,3,4-saturated_fatty_acyl_CoA + oxidized_electron_transfer_flavoprotein + H+ <=> trans-2-enoyl-CoA + reduced_flavodoxin
|
1.3.8
|
–
|
M
|
|
MetaCyc:
ACYLCOADEHYDROG-RXN
|
|
|
|
butyryl-CoA + oxidized_electron_transfer_flavoprotein + H+ <=> crotonyl-CoA + reduced_flavodoxin
|
1.3.8.1
short-chain acyl-CoA dehydrogenase
|
–
|
M
|
|
MetaCyc:
BUTYRYL-COA-DEHYDROGENASE-RXN
|
|
|
|
gamma-butyrobetainyl-CoA + oxidized_electron_transfer_flavoprotein + H+ <=> (E)-4-(trimethylammonio)but-2-enoyl-CoA + reduced_flavodoxin
|
1.3.8.13
crotonobetainyl-CoA reductase
|
–
|
M
|
|
MetaCyc:
CROBETREDUCT-RXN
|
|
|
|
N,N-dimethylglycine + tetrahydrofolate + oxidized_electron_transfer_flavoprotein + H+ <=> sarcosine + 5,10-methylenetetrahydrofolate + reduced_flavodoxin
|
1.5.8.4
dimethylglycine dehydrogenase
|
–
|
M
|
|
MetaCyc:
DIMETHYLGLYCINE-DEHYDROGENASE-RXN
|
|
|
|
reduced_flavodoxin + inactive_lactoyl-CoA_dehydratase + ATP + H2O <=> reduced_flavodoxin + lactoyl-CoA_dehydratase + ADP + phosphate + H+
|
5.6.1.9
(R)-2-hydroxyacyl-CoA dehydratase activating ATPase
|
–
|
|
|
MetaCyc:
EICOMP-RXN
|
|
|
|
reduced_flavodoxin + NAD+ <=> oxidized_electron_transfer_flavoprotein + NADH + H+
|
1.5.1.M1
|
–
|
|
|
MetaCyc:
ETFCLOS-RXN
|
|
|
|
glutaryl-CoA + oxidized_electron_transfer_flavoprotein + H+ <=> glutaconyl-CoA + reduced_flavodoxin
|
not assigned
|
–
|
M
|
|
MetaCyc:
GLUTARYL-COA-DEHYDROG-RXN
|
|
|
|
glutaryl-CoA + oxidized_electron_transfer_flavoprotein + H+ <=> crotonyl-CoA + CO2 + reduced_flavodoxin
|
1.3.8.6
glutaryl-CoA dehydrogenase (ETF)
|
–
|
|
|
MetaCyc:
GLUTARYL-COA-DEHYDROGENASE-RXN
|
|
|
|
long-chain_2,3,4-saturated_fatty_acyl_CoA + oxidized_electron_transfer_flavoprotein + H+ <=> trans-2-hexadecenoyl-CoA + reduced_flavodoxin
|
1.3.8.8
long-chain acyl-CoA dehydrogenase
|
–
|
|
|
MetaCyc:
LONG-CHAIN-ACYL-COA-DEHYDROGENASE-RXN
|
|
|
|
isobutyryl-CoA + oxidized_electron_transfer_flavoprotein + H+ <=> methacryloyl-CoA + reduced_flavodoxin
|
1.3.8.5
2-methyl-branched-chain-enoyl-CoA reductase
|
–
|
M
|
|
MetaCyc:
MEPROPCOA-FAD-RXN
|
|
|
|
propionyl-CoA + oxidized_electron_transfer_flavoprotein + H+ <=> acryloyl-CoA + reduced_flavodoxin
|
1.3.8.1
short-chain acyl-CoA dehydrogenase
|
–
|
M
|
|
MetaCyc:
PROPCOASYN-RXN
|
|
|
|
cyclohex-1-ene-1-carbonyl-CoA + oxidized_electron_transfer_flavoprotein + H+ <=> cyclohexa-1,5-diene-1-carbonyl-CoA + reduced_flavodoxin
|
1.3.8.10
cyclohex-1-ene-1-carbonyl-CoA dehydrogenase
|
–
|
M
|
|
MetaCyc:
R265-RXN
|
|
|
|
cyclohexanecarboxyl-CoA + oxidized_electron_transfer_flavoprotein + H+ <=> cyclohex-1-ene-1-carbonyl-CoA + reduced_flavodoxin
|
1.3.8.11
cyclohexane-1-carbonyl-CoA dehydrogenase (electron-transfer flavoprotein)
|
–
|
M
|
|
MetaCyc:
R282-RXN
|
|
|
|
S-adenosyl-L-methionine + inactive_ribonucleoside_triphosphate_reductase + reduced_flavodoxin <=> active_ribonucleoside_triphosphate_reductase + 5''-deoxyadenosine + L-methionine + reduced_flavodoxin + H+
|
1.97.1
|
–
|
|
|
MetaCyc:
RNTRACTIV-RXN
|
|
|
|
medium-chain_2,3,4-saturated_fatty_acyl_CoA + oxidized_electron_transfer_flavoprotein + H+ <=> trans-2-hexenoyl-CoA + reduced_flavodoxin
|
1.3.8.7
medium-chain acyl-CoA dehydrogenase
|
–
|
|
|
MetaCyc:
RXN-11734
|
|
|
|
citronellyl-CoA + oxidized_electron_transfer_flavoprotein + H+ <=> cis-geranyl-CoA + reduced_flavodoxin
|
1.3.8
|
–
|
M
|
|
MetaCyc:
RXN-11915
|
|
|
|
3-methylthiopropionyl-CoA + oxidized_electron_transfer_flavoprotein + H+ <=> 3-(methylthio)acryloyl-CoA + reduced_flavodoxin
|
1.3.8
|
–
|
M
|
|
MetaCyc:
RXN-12572
|
|
|
|
short-chain_2,3,4-saturated_fatty_acyl_CoA + oxidized_electron_transfer_flavoprotein + H+ <=> short-chain_(2E)-2-enoyl-CoA + reduced_flavodoxin
|
1.3.8.1
short-chain acyl-CoA dehydrogenase
|
–
|
|
|
MetaCyc:
RXN-13449
|
|
|
|
very-long-chain_2,3,4-saturated_fatty_acyl_CoA + oxidized_electron_transfer_flavoprotein + H+ <=> very-long-chain_(2E)-2-enoyl-CoA + reduced_flavodoxin
|
1.3.8.9
very-long-chain acyl-CoA dehydrogenase
|
–
|
|
|
MetaCyc:
RXN-13451
|
|
|
|
decanoyl-CoA + oxidized_electron_transfer_flavoprotein + H+ <=> trans-2-decenoyl-CoA + reduced_flavodoxin
|
1.3.8.7
medium-chain acyl-CoA dehydrogenase
|
–
|
M
|
|
MetaCyc:
RXN-13615
|
|
|
|
palmitoyl-[acyl-carrier_protein] + reduced_flavodoxin + O2 <=> pimeloyl-[acyl-carrier_protein] + an_n-alkanal + flavin + H2O + H+
|
1.14.14.46
pimeloyl-[acyl-carrier protein] synthase
|
–
|
M
|
|
MetaCyc:
RXN-13834
|
|
|
|
palmitoyl-[acyl-carrier_protein] + reduced_flavodoxin + O2 <=> 7-hydroxy-long-chain_acyl-[acp] + flavin + H2O
|
not assigned
|
–
|
|
|
MetaCyc:
RXN-13835
|
|
|
|
7-hydroxy-long-chain_acyl-[acp] + reduced_flavodoxin + O2 <=> 7,8-dihydroxy-long-chain_acyl-[acp] + flavin + H2O
|
not assigned
|
–
|
|
|
MetaCyc:
RXN-13836
|
|
|
|
7,8-dihydroxy-long-chain_acyl-[acp] + O2 + reduced_flavodoxin <=> a_7-oxoheptanoyl-[acyl-carrier_protein] + an_n-alkanal + H2O + flavin
|
not assigned
|
–
|
|
|
MetaCyc:
RXN-13991
|
|
|
|
myristoyl-CoA + oxidized_electron_transfer_flavoprotein + H+ <=> 2-tetradecenoyl-CoA + reduced_flavodoxin
|
1.3.8.8
long-chain acyl-CoA dehydrogenase
|
–
|
M
|
|
MetaCyc:
RXN-14131
|
|
|
|
octanoyl-CoA + oxidized_electron_transfer_flavoprotein + H+ <=> 2-octenoyl-CoA + reduced_flavodoxin
|
1.3.8.7
medium-chain acyl-CoA dehydrogenase
|
–
|
M
|
|
MetaCyc:
RXN-14229
|
|
|
|
lauroyl-CoA + oxidized_electron_transfer_flavoprotein + H+ <=> trans-2-dodecenoyl-CoA + reduced_flavodoxin
|
1.3.8.7
medium-chain acyl-CoA dehydrogenase
|
–
|
|
|
MetaCyc:
RXN-14262
|
|
|
|
hexanoyl-CoA + oxidized_electron_transfer_flavoprotein + H+ <=> trans-2-hexenoyl-CoA + reduced_flavodoxin
|
1.3.8.7
medium-chain acyl-CoA dehydrogenase
|
–
|
M
|
|
MetaCyc:
RXN-14278
|
|
|
|
L-prolyl-[PigG_prolyl-carrier_protein] + oxidized_electron_transfer_flavoprotein + H+ <=> 1H-pyrrole-2-carbonyl-[PigG_prolyl-carrier_protein] + reduced_flavodoxin
|
1.3.8.14
L-prolyl-[peptidyl-carrier protein] dehydrogenase
|
–
|
M
|
|
MetaCyc:
RXN-15780
|
|
|
|
S-adenosyl-L-methionine + 4-amino-1-(beta-D-glucuronosyl)pyrimidin-2(1H)-one + reduced_flavodoxin <=> cytosyl-alpha-L-arabinopyranose + CO2 + 5''-deoxyadenosine + L-methionine + flavin + H+
|
1.3.98
|
–
|
|
|
MetaCyc:
RXN-15942
|
|
|
|
1-(6-hydroxypyrid-3-yl)-4-(methylamino)-butan-1-one + H2O + oxidized_electron_transfer_flavoprotein + H+ <=> 6-hydroxy-3-succinoylsemialdehyde-pyridine + methylamine + reduced_flavodoxin
|
1.5.8.M1
|
–
|
M
|
|
MetaCyc:
RXN-16529
|
|
|
|
palmitoyl-CoA + oxidized_electron_transfer_flavoprotein + H+ <=> trans-2-hexadecenoyl-CoA + reduced_flavodoxin
|
1.3.8.9
very-long-chain acyl-CoA dehydrogenase
|
–
|
M
|
|
MetaCyc:
RXN-16540
|
|
|
|
(11Z)-hexadec-11-enoyl-CoA + oxidized_electron_transfer_flavoprotein + H+ <=> (2E,11Z)-hexadec-2,11-dienoyl-CoA + reduced_flavodoxin
|
1.3.8.9
very-long-chain acyl-CoA dehydrogenase
|
–
|
M
|
|
MetaCyc:
RXN-16557
|
|
|
|
oleoyl-CoA + oxidized_electron_transfer_flavoprotein + H+ <=> 2-trans-9-trans-octadecendienoyl-CoA + reduced_flavodoxin
|
1.3.8.8
long-chain acyl-CoA dehydrogenase
|
–
|
M
|
|
MetaCyc:
RXN-17775
|
|
|
|
(7Z)-hexadecenoyl-CoA + oxidized_electron_transfer_flavoprotein + H+ <=> (2E,7Z)-hexadecenoyl-CoA + reduced_flavodoxin
|
1.3.8.8
long-chain acyl-CoA dehydrogenase
|
–
|
M
|
|
MetaCyc:
RXN-17779
|
|
|
|
(5Z)-tetradecenoyl-CoA + oxidized_electron_transfer_flavoprotein + H+ <=> 2-trans,5-cis-tetradecadienoyl-CoA + reduced_flavodoxin
|
1.3.8.8
long-chain acyl-CoA dehydrogenase
|
–
|
M
|
|
MetaCyc:
RXN-17783
|
|
|
|
cis-vaccenoyl-CoA + oxidized_electron_transfer_flavoprotein + H+ <=> (2E,11Z)-octadecenoyl-CoA + reduced_flavodoxin
|
1.3.8
|
–
|
|
|
MetaCyc:
RXN-17784
|
|
|
|
palmitoleoyl-CoA + oxidized_electron_transfer_flavoprotein + H+ <=> (2E,9Z)-hexadecenoyl-CoA + reduced_flavodoxin
|
1.3.8
|
–
|
|
|
MetaCyc:
RXN-17788
|
|
|
|
(7Z)-tetradecenoyl-CoA + oxidized_electron_transfer_flavoprotein + H+ <=> (2E,7Z)-tetradecenoyl-CoA + reduced_flavodoxin
|
1.3.8
|
–
|
|
|
MetaCyc:
RXN-17792
|
|
|
|
(5Z)-dodecenoyl-CoA + oxidized_electron_transfer_flavoprotein + H+ <=> (2E,5Z)-dodecenoyl-CoA + reduced_flavodoxin
|
1.3.8
|
–
|
|
|
MetaCyc:
RXN-17796
|
|
|
|
S-adenosyl-L-methionine + vitamin_K2 + reduced_flavodoxin <=> 8-methylmenaquinone-8 + S-adenosyl-L-homocysteine + L-methionine + 5''-deoxyadenosine + flavin + H+
|
2.1.1.350
menaquinone C8-methyltransferase
|
–
|
|
|
MetaCyc:
RXN-18517
|
|
|
|
S-adenosyl-L-methionine + 2-demethylmenaquinone-8 + reduced_flavodoxin <=> 2-demethyl-8-methylmenaquinone-8 + S-adenosyl-L-homocysteine + L-methionine + 5''-deoxyadenosine + flavin + H+
|
2.1.1.350
menaquinone C8-methyltransferase
|
–
|
|
|
MetaCyc:
RXN-18519
|
|
|
|
L-prolyl-[PltL_prolyl-carrier_protein] + oxidized_electron_transfer_flavoprotein + H+ <=> 1H-pyrrole-2-carbonyl-[PltL_prolyl-carrier_protein] + reduced_flavodoxin
|
1.3.8.14
L-prolyl-[peptidyl-carrier protein] dehydrogenase
|
–
|
M
|
|
MetaCyc:
RXN-19066
|
|
|
|
(L-prolyl)-[peptidyl-carrier_protein] + oxidized_electron_transfer_flavoprotein + H+ <=> (1H-pyrrole-2-carbonyl)-[peptidyl-carrier_protein] + reduced_flavodoxin
|
1.3.8.14
L-prolyl-[peptidyl-carrier protein] dehydrogenase
|
–
|
|
|
MetaCyc:
RXN-19070
|
|
|
|
L-prolyl-[Bmp1_prolyl-carrier_protein] + oxidized_electron_transfer_flavoprotein + H+ <=> 1H-pyrrole-2-carbonyl-[Bmp1_prolyl-carrier_protein] + reduced_flavodoxin
|
1.3.8.14
L-prolyl-[peptidyl-carrier protein] dehydrogenase
|
–
|
M
|
|
MetaCyc:
RXN-19071
|
|
|
|
7-carboxy-4-methyl-5-oxoheptanoyl-CoA + oxidized_electron_transfer_flavoprotein + H+ <=> (2E)-7-carboxy-4-methyl-5-oxohept-2-enoyl-CoA + reduced_flavodoxin
|
1.3.8
|
–
|
M
|
|
MetaCyc:
RXN-19801
|
|
|
|
3-Phenylpropionic_acid + oxidized_electron_transfer_flavoprotein + H+ <=> Cinnamic_acid + reduced_flavodoxin
|
1.3.8.15
3-(aryl)acrylate reductase
|
–
|
M
|
|
MetaCyc:
RXN-19882
|
|
|
|
Indole-3-propionic_acid + oxidized_electron_transfer_flavoprotein + H+ <=> indole-3-acrylic_acid + reduced_flavodoxin
|
1.3.8.15
3-(aryl)acrylate reductase
|
–
|
M
|
|
MetaCyc:
RXN-19885
|
|
|
|
4-hydroxyphenylpropionic_acid + oxidized_electron_transfer_flavoprotein + H+ <=> p-coumaric_acid + reduced_flavodoxin
|
1.3.8.15
3-(aryl)acrylate reductase
|
–
|
M
|
|
MetaCyc:
RXN-19888
|
|
|
|
reduced_flavodoxin + inactive_(R)-2-hydroxyisocaproyl-CoA_dehydratase + ATP + H2O <=> reduced_flavodoxin + active_(R)-2-hydroxyisocaproyl-CoA_dehydratase + ADP + phosphate + H+
|
5.6.1.9
(R)-2-hydroxyacyl-CoA dehydratase activating ATPase
|
–
|
|
|
MetaCyc:
RXN-19890
|
|
|
|
reduced_flavodoxin + inactive_(R)-2-hydroxyglutaryl-CoA_dehydratase + ATP + H2O <=> reduced_flavodoxin + active_(R)-2-hydroxyglutaryl-CoA_dehydratase + ADP + phosphate + H+
|
5.6.1.9
(R)-2-hydroxyacyl-CoA dehydratase activating ATPase
|
–
|
|
|
MetaCyc:
RXN-19891
|
|
|
|
reduced_flavodoxin + inactive_(R)-phenyllactoyl-CoA_dehydratase + ATP + H2O <=> reduced_flavodoxin + active_(R)-phenyllactoyl-CoA_dehydratase + ADP + phosphate + H+
|
5.6.1.9
(R)-2-hydroxyacyl-CoA dehydratase activating ATPase
|
–
|
|
|
MetaCyc:
RXN-19892
|
|
|
|
reduced_flavodoxin + Acetylene + ATP + H2O <=> flavin + ethylene + H2 + ADP + phosphate + H+
|
1.19.6.1
nitrogenase (flavodoxin)
|
–
|
|
|
MetaCyc:
RXN-20189
|
|
|
|
(4S)-homoplatensicyl-CoA + oxidized_electron_transfer_flavoprotein + H+ <=> homoplatensic-4-enyl-CoA + reduced_flavodoxin
|
1.3.8
|
–
|
M
|
|
MetaCyc:
RXN-21751
|
|
|
|
2-methyl_branched_2,3,4-saturated_fatty_acyl-CoA + oxidized_electron_transfer_flavoprotein + H+ <=> (2E)-2-methyl-2-enoyl-CoA + reduced_flavodoxin
|
1.3.8
|
–
|
|
|
MetaCyc:
RXN-21754
|
|
|
|
valproyl-CoA + oxidized_electron_transfer_flavoprotein + H+ <=> (2E)-2-propylpent-2-enoyl-CoA + reduced_flavodoxin
|
1.3.8.5
2-methyl-branched-chain-enoyl-CoA reductase
|
–
|
M
|
|
MetaCyc:
RXN-21765
|
|
|
|
pentanoyl-CoA + oxidized_electron_transfer_flavoprotein + H+ <=> 2-pentenoyl-CoA + reduced_flavodoxin
|
1.3.8
|
–
|
M
|
|
MetaCyc:
RXN-21769
|
|
|
|
short-chain_2-methyl_fatty_acyl-CoA + oxidized_electron_transfer_flavoprotein + H+ <=> short-chain_(2E)-2-methyl-2-enoyl-CoA + reduced_flavodoxin
|
1.3.8.5
2-methyl-branched-chain-enoyl-CoA reductase
|
–
|
M
|
|
MetaCyc:
RXN-21774
|
|
|
|
medium-chain_2-methyl_fatty_acyl-CoA + oxidized_electron_transfer_flavoprotein + H+ <=> medium-chain_(2E)-2-methyl-2-enoyl-CoA + reduced_flavodoxin
|
1.3.8.8
long-chain acyl-CoA dehydrogenase
|
–
|
M
|
|
MetaCyc:
RXN-21775
|
|
|
|
long-chain_2-methyl_fatty_acyl-CoA + oxidized_electron_transfer_flavoprotein + H+ <=> long-chain_(2E)-2-methyl-2-enoyl-CoA + reduced_flavodoxin
|
1.3.8.8
long-chain acyl-CoA dehydrogenase
|
–
|
M
|
|
MetaCyc:
RXN-21776
|
|
|
|
4-methylpentanoate + oxidized_electron_transfer_flavoprotein + H+ <=> (E)-4-methyl-2-pentenoate + reduced_flavodoxin
|
1.3.8.15
3-(aryl)acrylate reductase
|
–
|
|
|
MetaCyc:
RXN-21788
|
|
|
|
NAD+ + electron-transfer_quinol + reduced_flavodoxin <=> NADH + electron-transfer_quinone + reduced_flavodoxin + H+
|
1.19.1.M1
|
–
|
|
|
MetaCyc:
RXN-21798
|
|
|
|
acetyl-CoA + oxidized_electron_transfer_flavoprotein + NADPH + CO2 + H+ <=> glyoxylate + propionyl-CoA + CoA + reduced_flavodoxin + NADP+
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-2802
|
|
|
|
(R)-2-benzylsuccinyl-CoA + oxidized_electron_transfer_flavoprotein + H+ <=> (E)-2-benzylidenesuccinyl-CoA + reduced_flavodoxin
|
1.3.8.3
(R)-benzylsuccinyl-CoA dehydrogenase
|
–
|
M
|
|
MetaCyc:
RXN-865
|
|
|
|
(2S)-methylsuccinyl-CoA + oxidized_electron_transfer_flavoprotein + H+ <=> 2-methylfumaryl-CoA + reduced_flavodoxin
|
1.3.8.12
(2S)-methylsuccinyl-CoA dehydrogenase
|
–
|
M
|
|
MetaCyc:
RXN-8959
|
|
|
|
isovaleryl-CoA + oxidized_electron_transfer_flavoprotein + H+ <=> 3-methylcrotonoyl-CoA + reduced_flavodoxin
|
1.3.8.4
isovaleryl-CoA dehydrogenase
|
–
|
M
|
|
MetaCyc:
RXN0-2301
|
|
|
|
L-prolyl-[RedO_prolyl-carrier_protein] + oxidized_electron_transfer_flavoprotein + H+ <=> 1H-pyrrole-2-carbonyl-[RedO_prolyl-carrier_protein] + reduced_flavodoxin
|
1.3.8.14
L-prolyl-[peptidyl-carrier protein] dehydrogenase
|
–
|
M
|
|
MetaCyc:
RXN1A0-6108
|
|
|
|
8-phenyloctanoyl-CoA + oxidized_electron_transfer_flavoprotein + H+ <=> (2E)-phenyloct-2-enoyl-CoA + reduced_flavodoxin
|
1.3.8.7
medium-chain acyl-CoA dehydrogenase
|
–
|
|
|
MetaCyc:
RXN1G01-39
|
|
|
|
stearoyl-CoA + oxidized_electron_transfer_flavoprotein + H+ <=> trans-2-octadecenoyl-CoA + reduced_flavodoxin
|
1.3.8.7
medium-chain acyl-CoA dehydrogenase
|
–
|
|
|
MetaCyc:
RXN1G01-40
|
|
|
|
oxidized_electron_transfer_flavoprotein + e- + H+ <=> reduced_flavodoxin
|
not assigned
|
–
|
|
|
MetaCyc:
RXN66-548
|
|
|
|
ubiquinone + reduced_flavodoxin <=> ubiquinol + oxidized_electron_transfer_flavoprotein + H+
|
1.5.5.1
electron-transferring-flavoprotein dehydrogenase
|
–
|
|
|
MetaCyc:
RXN66-550
|
|
|
|
sarcosine + oxidized_electron_transfer_flavoprotein + tetrahydrofolate + H+ <=> glycine + 5,10-methenyltetrahydrofolate + reduced_flavodoxin
|
1.5.8
|
–
|
M
|
|
MetaCyc:
RXN66-577
|
|
|
|
sarcosine + H2O + oxidized_electron_transfer_flavoprotein + H+ <=> glycine + formaldehyde + reduced_flavodoxin
|
1.5.8.3
sarcosine dehydrogenase
|
–
|
M
|
|
MetaCyc:
SARCOSINE-DEHYDROGENASE-RXN
|
|
|
|
S-adenosyl-L-methionine + formate_acetyltransferase-glycine + reduced_flavodoxin <=> formate_acetyltransferase-glycine + 5''-deoxyadenosine + L-methionine + reduced_flavodoxin + H+
|
1.97.1.4
[formate-C-acetyltransferase]-activating enzyme
|
–
|
|
|
MetaCyc:
TDCEACT-RXN
|
|
|
|
ethylbenzene + reduced_flavodoxin + O2 <=> 2-phenylethanol + 2-phenylethanol + reduced_flavodoxin + O2
|
1.14.14.1
unspecific monooxygenase
|
–
|
|
|
BRENDA:
BS388662
|
|
|
|
24,25-dihydrolanosterol + reduced_flavodoxin + O2 <=> (3beta,5alpha)-4,4-dimethylcholesta-8,14-dien-3-ol + formate + flavin + H2O
|
1.14.14.154
sterol 14alpha-demethylase
|
–
|
|
|
BRENDA:
BS394645
|
|
|
|
24,25-dihydrolanosterol + reduced_flavodoxin + O2 <=> 4,4-dimethyl-5alpha-cholesta-8,14-dien-3beta-ol + formate + flavin + H2O
|
1.14.14.154
sterol 14alpha-demethylase
|
–
|
|
|
BRENDA:
BS186736
|
|
|
|
lanosterol + reduced_flavodoxin + O2 <=> 4,4-dimethyl-5alpha-cholesta-8,24-dien-3beta-ol + formate + flavin + H2O
|
1.14.14.154
sterol 14alpha-demethylase
|
–
|
|
|
BRENDA:
BS386554
|
|
|
|
16alpha-hydroxytestosterone + 3 O2 + 3 reduced_flavodoxin <=> estriol + formate + 4 H2O + 3 flavin
|
1.14.14.14
aromatase
|
–
|
|
|
BRENDA:
BS425309
|
|
|
|
24-methylene-24,25-dihydrolanosterol + reduced_flavodoxin + O2 <=> 4,4-dimethyl-ergosta-8,14,24(28)-trien-3beta-ol + formate + flavin + H2O
|
1.14.14.154
sterol 14alpha-demethylase
|
–
|
|
|
BRENDA:
BS186737
|
|
|
|
24(28)-methylene-24,25-dihydrolanosterol + reduced_flavodoxin + O2 <=> 4,4-dimethyl-ergosta-8,14,24(28)-trien-3beta-ol + formate + flavin + H2O
|
1.14.14.154
sterol 14alpha-demethylase
|
–
|
|
|
BRENDA:
BS407917
|
|
|
|
7-lanostene-3beta,32-diol + reduced_flavodoxin + O2 <=> 4,4-dimethylcholesta-7,14-dien-3beta-ol + formate + flavin + H2O
|
1.14.14.154
sterol 14alpha-demethylase
|
–
|
|
|
BRENDA:
BS186740
|
|
|
|
8-lanostene-3beta,32-diol + reduced_flavodoxin + O2 <=> 4,4-dimethylcholesta-7,14-dien-3beta-ol + formate + flavin + H2O
|
1.14.14.154
sterol 14alpha-demethylase
|
–
|
|
|
BRENDA:
BS186739
|
|
|
|
7-lanosten-3beta-ol + reduced_flavodoxin + O2 <=> 4,4-dimethylcholesta-7,14-dien-3beta-ol + formate + flavin + H2O
|
1.14.14.154
sterol 14alpha-demethylase
|
–
|
|
|
BRENDA:
BS186741
|
|
|
|
lanosterol + reduced_flavodoxin + O2 <=> 4,4-dimethylcholesta-8,14,24-trienol + formate + flavin + H2O
|
1.14.14.154
sterol 14alpha-demethylase
|
–
|
|
|
BRENDA:
BS386553
|
|
|
|
24,28-dihydroobtusifoliol + reduced_flavodoxin + O2 <=> 4alpha-methyl-5alpha-ergosta-8,14-dien-3beta-ol + formate + flavin + H2O
|
1.14.14.154
sterol 14alpha-demethylase
|
–
|
|
|
BRENDA:
BS186734
|
|
|
|
eburicol + O2 + reduced_flavodoxin + O2 <=> 2-(3-hydroxy-4,4,10,13-tetramethyl-2,3,4,5,6,7,10,11,12,13,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl)-6-methyl-5-methylene-heptanoic_acid + formate + flavin + H2O
|
1.14.14.154
sterol 14alpha-demethylase
|
–
|
|
|
BRENDA:
BS186738
|
|
|
|
24-methylene-24,25-dihydrolanosterol + reduced_flavodoxin + O2 <=> 14alpha-demethyl-24-methylene-4alpha-methyl-5alpha-ergosta-8,14,24-trien-3beta-ol + formate + flavin + H2O
|
1.14.14.154
sterol 14alpha-demethylase
|
–
|
|
|
BRENDA:
BS375729
|
|
|
|
24,25-dihydrolanosterol + reduced_flavodoxin + O2 <=> 24,25-dihydro-4,4-dimethyl-5alpha-cholesta-8,14,24-trien-3beta-ol + formate + flavin + H2O
|
1.14.14.154
sterol 14alpha-demethylase
|
–
|
|
|
BRENDA:
BS427292
|
|
|
|
palmitoyl-CoA + flavin <=> trans-2-hexadecenoyl-CoA + reduced_flavodoxin
|
1.3.8.8
long-chain acyl-CoA dehydrogenase
1.3.8.9
very-long-chain acyl-CoA dehydrogenase
|
–
–
|
|
|
BRENDA:
BR50095
|
|
|
|
sertraline + reduced_flavodoxin + O2 <=> demethylsertraline + formaldehyde + flavin + H2O
|
1.14.14.1
unspecific monooxygenase
|
–
|
|
|
BRENDA:
BS418074
|
|
|
|
(R)-nicotine + O2 + reduced_flavodoxin + O2 <=> (R)-nornicotine + formaldehyde + flavin + H2O
|
1.14.14.B11
|
–
|
|
|
BRENDA:
BS427254
|
|
|
|
Nicotine + reduced_flavodoxin + O2 <=> (S)-nornicotine + formaldehyde + flavin + H2O
|
1.14.14.B11
|
–
|
|
|
BRENDA:
BS427259
|
|
|
|
Nicotine + reduced_flavodoxin + O2 <=> Nornicotine + formaldehyde + flavin + H2O
|
1.14.14.B11
|
–
|
|
|
BRENDA:
BR48984
|
|
|
|
2-pentenoyl-CoA + reduced_flavodoxin <=> pentanoyl-CoA + electron_transfer_protein
|
1.3.8.1
short-chain acyl-CoA dehydrogenase
|
–
|
|
|
BRENDA:
BS370163
|
|
|
|
CO + H2O + flavin <=> CO2 + reduced_flavodoxin
|
1.2.7.4
anaerobic carbon monoxide dehydrogenase
|
–
|
|
|
BRENDA:
BS359371
|
|
|
|
CO + H2O + flavodoxin <=> CO2 + reduced_flavodoxin
|
1.2.7.4
anaerobic carbon monoxide dehydrogenase
|
–
|
|
|
BRENDA:
BS258305
|
|
|
|
L-trihomomethionine + 2 O2 + 2 reduced_flavodoxin <=> L-trihomomethionine + CO2 + 3 H2O + 2 flavin
|
1.14.14.42
homomethionine N-monooxygenase
|
–
|
|
|
BRENDA:
BS438388
|
|
|
|
L-trihomomethionine + 2 O2 + 2 reduced_flavodoxin <=> 4-methylthiohexanaldoxime + CO2 + 3 H2O + 2 flavin
|
1.14.14.42
homomethionine N-monooxygenase
|
–
|
|
|
BRENDA:
BS438387
|
|
|
|
L-dihomomethionine + 2 O2 + 2 reduced_flavodoxin <=> 4-methylthiopentanaldoxime + CO2 + 3 H2O + 2 flavin
|
1.14.14.42
homomethionine N-monooxygenase
|
–
|
|
|
BRENDA:
BS438371
|
|
|
|
benzyl_methyl_sulfide + reduced_flavodoxin + O2 <=> [(methylsulfinyl)methyl]benzene + benzyl_methyl_sulfone + flavin + H2O
|
1.14.14.1
unspecific monooxygenase
|
–
|
|
|
BRENDA:
BS428434
|
|
|
|
alpha-tocopherol + reduced_flavodoxin + O2 <=> alpha-13''-hydroxy-tocopherol + flavin + H2O
|
1.14.14.94
leukotriene-B4 20-monooxygenase
|
–
|
|
|
BRENDA:
BS414275
|
|
|
|
1beta-hydroxy-5-epiaristolochene + reduced_flavodoxin + O2 <=> capsidiol + flavin + H2O
|
1.14.14.149
5-epiaristolochene 1,3-dihydroxylase
|
–
|
|
|
BRENDA:
BS413199
|
|
|
|
1-deoxycapsidiol + reduced_flavodoxin + O2 <=> capsidiol + flavin + H2O
|
1.14.14.149
5-epiaristolochene 1,3-dihydroxylase
|
–
|
|
|
BRENDA:
BS413162
|
|
|
|
syn-stemoden-19-al + reduced_flavodoxin + O2 <=> syn-stemoden-19-oate + flavin + H2O
|
1.14.14.111
9beta-pimara-7,15-diene oxidase
|
–
|
|
|
BRENDA:
BS419125
|
|
|
|
a_C21_steroid + reduced_flavodoxin + O2 <=> a_17alpha-hydroxy-C21-steroid + flavin + H2O
|
1.14.14.19
steroid 17alpha-monooxygenase
|
–
|
|
|
BRENDA:
BR36769
|
|
|
|
a_C21_steroid + reduced_flavodoxin + O2 <=> a_21-hydroxy-C21-steroid + flavin + H2O
|
1.14.14.16
steroid 21-monooxygenase
|
–
|
|
|
BRENDA:
BR29155
|
|
|
|
(25R)-cholest-5-ene-3beta,26-diol + reduced_flavodoxin + O2 <=> (25R)-cholest-5-ene-3beta,7alpha,26-triol + flavin + H2O
|
1.14.14.29
25/26-hydroxycholesterol 7alpha-hydroxylase
|
–
|
|
|
BRENDA:
BR48562
|
|
|
|
nerol + reduced_flavodoxin + O2 <=> (6E)-8-hydroxynerol + flavin + H2O
|
1.14.14.83
geraniol 8-hydroxylase
|
–
|
|
|
BRENDA:
BS415696
|
|
|
|
ethylmethylsulfide + reduced_flavodoxin + O2 <=> ethylmethylsulfoxide + flavin + H2O
|
1.14.14.1
unspecific monooxygenase
|
–
|
|
|
BRENDA:
BS414607
|
|
|
|
2-Chlorobenzoate + reduced_flavodoxin + O2 <=> 2-Chloro-4-hydroxybenzoate + flavin + H2O
|
1.14.14.92
benzoate 4-monooxygenase
|
–
|
|
|
BRENDA:
BS289258
|
|
|
|
oleic_acid + reduced_flavodoxin + O2 <=> omega-hydroxy_oleic_acid + dodecanedioic_acid + flavin + H2O
|
1.14.14.1
unspecific monooxygenase
|
–
|
|
|
BRENDA:
BS377415
|
|
|
|
7beta-hydroxy-ent-sandaracopimaradiene + reduced_flavodoxin + O2 <=> oryzalexin_D + flavin + H2O
|
1.14.14.70
ent-sandaracopimaradiene 3-hydroxylase
|
–
|
|
|
BRENDA:
BS429838
|
|
|
|
leucopelargonidin + reduced_flavodoxin + O2 <=> Leucocyanidin + flavin + H2O
|
1.14.14.82
flavonoid 3'-monooxygenase
|
–
|
|
|
BRENDA:
BS443712
|
|
|
|
5-epiaristolochene + 3 reduced_flavodoxin + 3 O2 <=> 2beta-hydroxy-epiaristolochene + 1beta-hydroxy-5-epiaristolochene + 1-deoxycapsidiol + 3 flavin + 3 H2O
|
1.14.14.151
premnaspirodiene oxygenase
|
–
|
|
|
BRENDA:
BS414152
|
|
|
|
5-epiaristolochene + reduced_flavodoxin + O2 <=> 1beta-hydroxy-5-epiaristolochene + flavin + H2O
|
1.14.14.149
5-epiaristolochene 1,3-dihydroxylase
|
–
|
|
|
BRENDA:
BS413230
|
|
|
|
eicosapentaenoic_acid + reduced_flavodoxin + O2 <=> 20-hydroxyeicosapentaenoic_acid + 19-hydroxyeicosapentaenoic_acid + flavin + H2O
|
1.14.14.1
unspecific monooxygenase
|
–
|
|
|
BRENDA:
BS414586
|
|
|
|
eicosapentaenoic_acid + reduced_flavodoxin + O2 <=> 20-hydroxyeicosapentaenoic_acid + flavin + H2O
|
1.14.14.1
unspecific monooxygenase
|
–
|
|
|
BRENDA:
BS414588
|
|
|
|
4-epi-eremophilene + reduced_flavodoxin + O2 <=> 2beta-hydroxy-epieremophilene + flavin + H2O
|
1.14.14.151
premnaspirodiene oxygenase
|
–
|
|
|
BRENDA:
BS414591
|
|
|
|
5-epiaristolochene + reduced_flavodoxin + O2 <=> 1-deoxycapsidiol + flavin + H2O
|
1.14.14.149
5-epiaristolochene 1,3-dihydroxylase
|
–
|
|
|
BRENDA:
BS413232
|
|
|
|
1-fluoro-4-methylsulfanylbenzene + reduced_flavodoxin + O2 <=> 4-fluorothioanisole_sulfoxide + flavin + H2O
|
1.14.14.1
unspecific monooxygenase
|
–
|
|
|
BRENDA:
BS414105
|
|
|
|
valencene + 2 reduced_flavodoxin + 2 O2 <=> alpha-nootkatol + beta-nootkatol + 2 flavin + 2 H2O
|
1.14.14.151
premnaspirodiene oxygenase
|
–
|
|
|
BRENDA:
BS415429
|
|
|
|
cedr-8-ene + reduced_flavodoxin + O2 <=> cedr-8-en-15-ol + flavin + H2O
|
1.14.14.151
premnaspirodiene oxygenase
|
–
|
|
|
BRENDA:
BS414415
|
|
|
|
delta-tocopherol + reduced_flavodoxin + O2 <=> delta-13''-hydroxy-tocopherol + flavin + H2O
|
1.14.14.94
leukotriene-B4 20-monooxygenase
|
–
|
|
|
BRENDA:
BS414532
|
|
|
|
indole + reduced_flavodoxin + O2 <=> (2Z)-2-(3-oxo-1,3-dihydro-2H-indol-2-ylidene)-1,2-dihydro-3H-indol-3-one + indirubin + flavin + H2O
|
1.14.14.1
unspecific monooxygenase
|
–
|
|
|
BRENDA:
BS428708
|
|
|
|
N-acetylindole + reduced_flavodoxin + O2 <=> 1-acetyl-1,2-dihydro-3H-indol-3-one + 1-acetyl-1,3-dihydro-2H-indol-2-one + flavin + H2O
|
1.14.14.1
unspecific monooxygenase
|
–
|
|
|
BRENDA:
BS428805
|
|
|
|
taxadien-5alpha-yl_acetate + reduced_flavodoxin + O2 <=> 10beta-hydroxytaxa-4(20),11-dien-5alpha-yl_acetate + flavin + H2O
|
1.14.14.105
taxane 10beta-hydroxylase
|
–
|
|
|
BRENDA:
BS386708
|
|
|
|
alpha-carotene + reduced_flavodoxin + O2 <=> lutein + flavin + H2O
|
1.14.14.158
carotenoid epsilon hydroxylase
|
–
|
|
|
BRENDA:
BS427347
|
|
|
|
linoleic_acid + reduced_flavodoxin + O2 <=> (9Z,12Z)-18-hydroxyoctadeca-9,12-dienoic_acid + flavin + H2O
|
1.14.14.1
unspecific monooxygenase
1.14.14.80
long-chain fatty acid omega-monooxygenase
|
–
–
|
|
|
BRENDA:
BS414804
|
|
|
|
1alpha-hydroxyvitamin_D2 + O2 + reduced_flavodoxin + H+ <=> 1alpha,25-dihydroxyvitamin_D2 + flavin + H2O
|
1.14.14.24
vitamin D 25-hydroxylase
|
–
|
|
|
BRENDA:
BS418210
|
|
|
|
7-dehydro-pregnenolone + reduced_flavodoxin + O2 <=> 7-dehydro-17alpha-hydroxypregnenolone + flavin + H2O
|
1.14.14.19
steroid 17alpha-monooxygenase
|
–
|
|
|
BRENDA:
BS427331
|
|
|
|
30-hydroxy-beta-amyrin + reduced_flavodoxin + O2 <=> 11-deoxoglycyrrhetinic_acid + flavin + H2O
|
1.14.14.152
beta-amyrin 11-oxidase
|
–
|
|
|
BRENDA:
BS416254
|
|
|
|
germacrene_A + reduced_flavodoxin + O2 <=> 12-hydroxygermacrene_A + flavin + H2O
|
1.14.14.95
germacrene A hydroxylase
|
–
|
|
|
BRENDA:
BS417033
|
|
|
|
beta-elemene + reduced_flavodoxin + O2 <=> elema-1,3,11(13)-trien-12-ol + flavin + H2O
|
1.14.14.95
germacrene A hydroxylase
|
–
|
|
|
BRENDA:
BS416722
|
|
|
|
citronellol + reduced_flavodoxin + O2 <=> (6E)-8-hydroxycitronellol + flavin + H2O
|
1.14.14.83
geraniol 8-hydroxylase
|
–
|
|
|
BRENDA:
BS417828
|
|
|
|
1alpha,25-dihydroxyvitamin_D2 + O2 + reduced_flavodoxin + H+ <=> 1alpha,25,26-trihydroxyvitamin_D2 + flavin + H2O
|
1.14.14.24
vitamin D 25-hydroxylase
|
–
|
|
|
BRENDA:
BS418208
|
|
|
|
1alpha,25-dihydroxyvitamin_D3 + O2 + reduced_flavodoxin + H+ <=> 1alpha,25,26-trihydroxyvitamin_D3 + flavin + H2O
|
1.14.14.24
vitamin D 25-hydroxylase
|
–
|
|
|
BRENDA:
BS418209
|
|
|
|
1,4-cineole + reduced_flavodoxin + H+ + O2 <=> 2-exo-hydroxy-1,4-cineole + flavin + H2O
|
1.14.14.56
1,8-cineole 2-exo-monooxygenase
|
–
|
|
|
BRENDA:
BS418190
|
|
|
|
1,8-cineole + reduced_flavodoxin + H+ + O2 <=> 2alpha-hydroxy-1,8-cineole + flavin + H2O
|
1.14.14.56
1,8-cineole 2-exo-monooxygenase
|
–
|
|
|
BRENDA:
BS418193
|
|
|
|
1,8-cineole + reduced_flavodoxin + H+ + O2 <=> 3alpha-hydroxy-1,8-cineole + flavin + H2O
|
1.14.14.56
1,8-cineole 2-exo-monooxygenase
|
–
|
|
|
BRENDA:
BS418194
|
|
|
|
dihydroartemisinic_aldehyde + reduced_flavodoxin + O2 <=> dihydroartemisinate + flavin + H2O
|
1.14.14.114
amorpha-4,11-diene 12-monooxygenase
|
–
|
|
|
BRENDA:
BS418582
|
|
|
|
docosahexaenoic_acid + reduced_flavodoxin + O2 <=> (4Z,7Z,10Z,13Z,16Z)-19,20-epoxydocosa-4,7,10,13,16-pentaenoate + flavin + H2O
|
1.14.14.B9
|
–
|
|
|
BRENDA:
BR51211
|
|
|
|
docosahexaenoic_acid + reduced_flavodoxin + O2 <=> (4Z,7Z,10Z,16Z,19Z)-13,14-epoxydocosa-4,7,10,16,19-pentaenoate + flavin + H2O
|
1.14.14.B9
|
–
|
|
|
BRENDA:
BR51212
|
|
|
|
docosahexaenoic_acid + reduced_flavodoxin + O2 <=> (4Z,7Z,13Z,16Z,19Z)-10,11-epoxydocosa-4,7,13,16,19-pentaenoate + flavin + H2O
|
1.14.14.B9
|
–
|
|
|
BRENDA:
BR51213
|
|
|
|
gamma-tocopherol + reduced_flavodoxin + O2 <=> 13''-hydroxy-gamma-tocopherol + flavin + H2O
|
1.14.14.78
phylloquinone omega-hydroxylase
1.14.14.94
leukotriene-B4 20-monooxygenase
|
–
–
|
|
|
BRENDA:
BS414635
|
|
|
|
docosapentaenoic_acid + reduced_flavodoxin + O2 <=> 22-hydroxydocosapentaenoic_acid + flavin + H2O
|
1.14.14.79
docosahexaenoic acid omega-hydroxylase
|
–
|
|
|
BRENDA:
BS430137
|
|
|
|
2 3,5,4''-trimethoxy-trans-stilbene + 2 reduced_flavodoxin + 2 O2 <=> 3-hydroxy-5,4''-dimethoxy-trans-stilbene + 3,5-dihydroxy-4''-methoxy-trans-stilbene + 2 flavin + 2 H2O
|
1.14.14.1
unspecific monooxygenase
|
–
|
|
|
BRENDA:
BS427960
|
|
|
|
tryprostatin_B + reduced_flavodoxin + O2 <=> demethoxyfumitremorgin_C + flavin + H2O
|
1.14.19.71
fumitremorgin C synthase
|
–
|
|
|
BRENDA:
BS424134
|
|
|
|
dehydroabietadienol + reduced_flavodoxin + O2 <=> dehydroabietadienal + flavin + H2O
|
1.14.14.145
abieta-7,13-dien-18-ol hydroxylase
|
–
|
|
|
BRENDA:
BS388506
|
|
|
|
myristic_acid + reduced_flavodoxin + O2 <=> 12-hydroxymyristic_acid + flavin + H2O
|
1.14.14.80
long-chain fatty acid omega-monooxygenase
|
–
|
|
|
BRENDA:
BS409904
|
|
|
|
11,14,17-Eicosatrienoic_acid + reduced_flavodoxin + O2 <=> 20-hydroxyeicosatrienoic_acid + flavin + H2O
|
1.14.14.79
docosahexaenoic acid omega-hydroxylase
|
–
|
|
|
BRENDA:
BS430151
|
|
|
|
3-hydroxypalmitate + reduced_flavodoxin + O2 <=> 3,16-dihydroxypalmitate + flavin + H2O
|
1.14.14.78
phylloquinone omega-hydroxylase
|
–
|
|
|
BRENDA:
BS429720
|
|
|
|
3-hydroxystearate + reduced_flavodoxin + O2 <=> 3,18-dihydroxystearate + flavin + H2O
|
1.14.14.78
phylloquinone omega-hydroxylase
|
–
|
|
|
BRENDA:
BS429722
|
|
|
|
ent-cassa-12,15-diene + reduced_flavodoxin + O2 <=> 3alpha-hydroxy-ent-cassadiene + flavin + H2O
|
1.14.14.70
ent-sandaracopimaradiene 3-hydroxylase
|
–
|
|
|
BRENDA:
BS429251
|
|
|
|
Allocryptopine + reduced_flavodoxin + O2 <=> 6-hydroxyallocryptopine + flavin + H2O
|
1.14.14.98
protopine 6-monooxygenase
|
–
|
|
|
BRENDA:
BS428150
|
|
|
|
17,17-dimethyl-18-norandrosta-1,4,13-trien-3-one + reduced_flavodoxin + O2 <=> 16beta-hydroxy-17,17-dimethyl-18-norandrosta-1,4,13-trien-3-one + 16alpha-hydroxy-17,17-dimethyl-18-norandrosta-1,4,13-trien-3-one + flavin + H2O
|
1.14.14.16
steroid 21-monooxygenase
|
–
|
|
|
BRENDA:
BS427845
|
|
|
|
17,17-dimethyl-18-norandrosta-1,4,13-trien-3-one + reduced_flavodoxin + O2 <=> 20beta-hydroxy-17,17-dimethyl-18-norandrosta-1,4,13-trien-3-one + flavin + H2O
|
1.14.14.16
steroid 21-monooxygenase
|
–
|
|
|
BRENDA:
BS427846
|
|
|
|
corycavine + reduced_flavodoxin + O2 <=> corynoloxine + flavin + H2O
|
1.14.14.98
protopine 6-monooxygenase
|
–
|
|
|
BRENDA:
BS428495
|
|
|
|
abscisic_acid + reduced_flavodoxin + O2 <=> phaseic_acid + flavin + H2O
|
1.14.14.137
(+)-abscisic acid 8'-hydroxylase
|
–
|
|
|
BRENDA:
BS427229
|
|
|
|
(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate + reduced_flavodoxin + O2 <=> (4Z,7Z,10Z,13Z,16Z)-20-hydroxydocosa-4,7,10,13,16-pentaenoate + flavin + H2O
|
1.14.14.B9
|
–
|
|
|
BRENDA:
BS429513
|
|
|
|
docosapentaenoic_acid + reduced_flavodoxin + O2 <=> (7Z,10Z,13Z,16Z)-19,20-epoxydocosa-7,10,13,16-tetraenoate + flavin + H2O
|
1.14.14.B9
|
–
|
|
|
BRENDA:
BS429521
|
|
|
|
docosapentaenoic_acid + reduced_flavodoxin + O2 <=> (7Z,10Z,13Z,19Z)-16,17-epoxydocosa-7,10,13,19-tetraenoate + flavin + H2O
|
1.14.14.B9
|
–
|
|
|
BRENDA:
BS429522
|
|
|
|
docosapentaenoic_acid + reduced_flavodoxin + O2 <=> (7Z,13Z,16Z,19Z)-10,11-epoxydocosa-7,13,16,19-tetraenoate + flavin + H2O
|
1.14.14.B9
|
–
|
|
|
BRENDA:
BS429523
|
|
|
|
arachidonic_acid + reduced_flavodoxin + O2 <=> 18-hydroxyarachidonic_acid + flavin + H2O
|
1.14.14.B9
|
–
|
|
|
BRENDA:
BS429897
|
|
|
|
dihydroartemisinic_alcohol + reduced_flavodoxin + O2 <=> dihydroartemisinic_aldehyde + flavin + H2O
|
1.14.14.114
amorpha-4,11-diene 12-monooxygenase
|
–
|
|
|
BRENDA:
BS418581
|
|
|
|
(E,Z)-indolyl-3-acetaldoxime + reduced_flavodoxin + O2 <=> 1-aci-nitro-2-indolyl-ethane + flavin + H2O
|
1.14.14.45
aromatic aldoxime N-monooxygenase
|
–
|
|
|
BRENDA:
BR52037
|
|
|
|
(E,Z)-indolyl-3-acetaldoxime + O2 + glutathione + reduced_flavodoxin <=> 1-aci-nitro-2-indolyl-ethane + H2O + flavin
|
1.14.14.43
(methylsulfanyl)alkanaldoxime N-monooxygenase
1.14.14.45
aromatic aldoxime N-monooxygenase
|
–
–
|
|
|
BRENDA:
BS439618
|
|
|
|
p-hydroxyphenylacetaldoxime + O2 + reduced_flavodoxin <=> 1-aci-nitro-2-(4-hydroxyphenyl)-ethane + H2O + flavin
|
1.14.14.40
phenylalanine N-monooxygenase
1.14.14.43
(methylsulfanyl)alkanaldoxime N-monooxygenase
1.14.14.45
aromatic aldoxime N-monooxygenase
|
–
–
–
|
|
|
BRENDA:
BS438021
|
|
|
|
(R,S)-cheilanthifoline + reduced_flavodoxin + O2 <=> (R,S)-stylopine + flavin + H2O
|
1.14.19.64
(S)-stylopine synthase
1.14.19.73
(S)-nandinine synthase
|
–
–
|
|
|
BRENDA:
BS386005
|
|
|
|
p-hydroxyphenylacetaldoxime + reduced_flavodoxin + N-acetyl-L-cysteine + O2 <=> S-(benzohydroximoyl)-N-acetyl-L-cysteine + flavin + 2 H2O
|
1.14.14.45
aromatic aldoxime N-monooxygenase
|
–
|
|
|
BRENDA:
BS439807
|
|
|
|
p-hydroxyphenylacetaldoxime + reduced_flavodoxin + L-cysteine + O2 <=> S-(benzohydroximoyl)-L-cysteine + flavin + 2 H2O
|
1.14.14.45
aromatic aldoxime N-monooxygenase
|
–
|
|
|
BRENDA:
BS439806
|
|
|
|
indole-3-acetonitrile + reduced_flavodoxin + O2 <=> hydroxy(1H-indol-3-yl)acetonitrile + flavin + 2 H2O
|
1.14.14.44
phenylacetaldehyde oxime monooxygenase
|
–
|
|
|
BRENDA:
BS439621
|
|
|
|
(E,Z)-indolyl-3-acetaldoxime + reduced_flavodoxin + O2 <=> hydroxy(1H-indol-3-yl)acetonitrile + flavin + 2 H2O
|
1.14.14.44
phenylacetaldehyde oxime monooxygenase
|
–
|
|
|
BRENDA:
BS439619
|
|
|
|
eicosapentaenoic_acid + reduced_flavodoxin + O2 <=> (5Z,8Z,11Z,14Z,17Z)-20-hydroxyicosa-5,8,11,14,17-pentaenoic_acid + flavin + H2O
|
1.14.14.79
docosahexaenoic acid omega-hydroxylase
|
–
|
|
|
BRENDA:
BS428701
|
|
|
|
(R,S)-norreticuline + reduced_flavodoxin + O2 <=> 2,10-dimethoxy-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-1,11-diol + flavin + 2 H2O
|
1.14.19.51
(S)-corytuberine synthase
|
–
|
|
|
BRENDA:
BS438567
|
|
|
|
(S)-orientaline + reduced_flavodoxin + O2 <=> 2,11-dimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-1,10-diol + flavin + 2 H2O
|
1.14.19.51
(S)-corytuberine synthase
|
–
|
|
|
BRENDA:
BS438601
|
|
|
|
(R,S)-codamine + reduced_flavodoxin + O2 <=> 2,11-dimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-1,10-diol + flavin + 2 H2O
|
1.14.19.51
(S)-corytuberine synthase
|
–
|
|
|
BRENDA:
BS438566
|
|
|
|
(S)-N-methylcoclaurine + reduced_flavodoxin + O2 <=> 2,11-dimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-1,10-diol + flavin + 2 H2O
|
1.14.19.51
(S)-corytuberine synthase
|
–
|
|
|
BRENDA:
BS438599
|
|
|
|
9,10-epoxystearic_acid + reduced_flavodoxin + O2 <=> 18-hydroxy-9(10)-epoxystearic_acid + flavin + H2O
|
1.14.14.79
docosahexaenoic acid omega-hydroxylase
1.14.14.80
long-chain fatty acid omega-monooxygenase
|
–
–
|
|
|
BRENDA:
BS430780
|
|
|
|
isolauric_acid + reduced_flavodoxin + O2 <=> 11-hydroxyisolauric_acid + flavin + H2O
|
1.14.14.80
long-chain fatty acid omega-monooxygenase
|
–
|
|
|
BRENDA:
BS433850
|
|
|
|
isomyristic_acid + reduced_flavodoxin + O2 <=> 13-hydroxyisomyristic_acid + flavin + H2O
|
1.14.14.80
long-chain fatty acid omega-monooxygenase
|
–
|
|
|
BRENDA:
BS433851
|
|
|
|
tridecanoate + reduced_flavodoxin + O2 <=> 13-hydroxytridecanoic_acid + flavin + H2O
|
1.14.14.80
long-chain fatty acid omega-monooxygenase
|
–
|
|
|
BRENDA:
BS434443
|
|
|
|
linolenic_acid + reduced_flavodoxin + O2 <=> 18-hydroxlinolenic_acid + flavin + H2O
|
1.14.14.80
long-chain fatty acid omega-monooxygenase
|
–
|
|
|
BRENDA:
BS433405
|
|
|
|
palmitoleic_acid + reduced_flavodoxin + O2 <=> 18-hydroxypalmitoleic_acid + flavin + H2O
|
1.14.14.80
long-chain fatty acid omega-monooxygenase
|
–
|
|
|
BRENDA:
BS434113
|
|
|
|
stearoyl-CoA + reduced_flavodoxin + O2 <=> 18-hydroxystearoyl-CoA + flavin + H2O
|
1.14.14.129
long-chain acyl-CoA omega-monooxygenase
|
–
|
|
|
BRENDA:
BS434404
|
|
|
|
xylene + reduced_flavodoxin + O2 <=> 3-methylbenzyl_alcohol + flavin + H2O
|
1.14.14.1
unspecific monooxygenase
|
–
|
|
|
BRENDA:
BS389125
|
|
|
|
(E,Z)-indolyl-3-acetaldoxime + reduced_flavodoxin + glutathione + O2 <=> S-[(E)-N-hydroxy(indol-3-yl)acetimidoyl]-L-glutathione + flavin + 2 H2O
|
1.14.14.45
aromatic aldoxime N-monooxygenase
|
–
|
|
|
BRENDA:
BR52036
|
|
|
|
p-hydroxyphenylacetaldoxime + reduced_flavodoxin + glutathione + O2 <=> S-[(Z)-N-hydroxy(p-hydroxyphenyl)acetimidoyl]-L-glutathione + flavin + 2 H2O
|
1.14.14.45
aromatic aldoxime N-monooxygenase
|
–
|
|
|
BRENDA:
BS438023
|
|
|
|
tetracycline + reduced_flavodoxin + O2 <=> 11a-hydroxy-tetracycline + flavin + H2O
|
1.14.13.231
tetracycline 11a-monooxygenase
|
–
|
|
|
BRENDA:
BS377859
|
|
|
|
(-)-alpha-pinene + reduced_flavodoxin + O2 <=> alpha-Pinene_oxide + flavin + H2O
|
1.14.14.1
unspecific monooxygenase
|
–
|
|
|
BRENDA:
BS399122
|
|
|
|
Apiforol + reduced_flavodoxin + O2 <=> luteoforol + flavin + H2O
|
1.14.14.82
flavonoid 3'-monooxygenase
|
–
|
|
|
BRENDA:
BS425931
|
|
|
|
o-Tolylacetonitrile + reduced_flavodoxin + O2 <=> (2R)-hydroxy-(2-methylphenyl)acetonitrile + flavin + H2O
|
1.14.14.77
phenylacetonitrile alpha-monooxygenase
|
–
|
|
|
BRENDA:
BS442164
|
|
|
|
3-tolylacetonitrile + reduced_flavodoxin + O2 <=> (2R)-hydroxy-(3-methylphenyl)acetonitrile + flavin + H2O
|
1.14.14.77
phenylacetonitrile alpha-monooxygenase
|
–
|
|
|
BRENDA:
BS442193
|
|
|
|
dehydroabietadienal + reduced_flavodoxin + O2 <=> dehydroabietadienoate + flavin + H2O
|
1.14.14.145
abieta-7,13-dien-18-ol hydroxylase
|
–
|
|
|
BRENDA:
BS388505
|
|
|
|
isopimaradienal + reduced_flavodoxin + O2 <=> (13S)-pimara-7,15-dien-18-oate + flavin + H2O
|
1.14.14.145
abieta-7,13-dien-18-ol hydroxylase
|
–
|
|
|
BRENDA:
BS388947
|
|
|
|
9'',9''-difluoro-(+)-S-abscisate + reduced_flavodoxin + O2 <=> 9'',9''-difluoro-8''-hydroxy-(+)-S-abscisate + flavin + H2O
|
1.14.14.137
(+)-abscisic acid 8'-hydroxylase
|
–
|
|
|
BRENDA:
BS379091
|
|
|
|
2,3-dihydrotabersonine + reduced_flavodoxin + O2 <=> 2,3-dihydro-16-hydroxytabersonine + flavin + H2O
|
1.14.14.103
tabersonine 16-hydroxylase
|
–
|
|
|
BRENDA:
BS427281
|
|
|
|
2,3-dihydro-3-hydroxytabersonine + reduced_flavodoxin + O2 <=> 2,3-dihydro-3,16-dihydroxytabersonine + flavin + H2O
|
1.14.14.103
tabersonine 16-hydroxylase
|
–
|
|
|
BRENDA:
BS427280
|
|
|
|
ent-kaurene + reduced_flavodoxin + O2 <=> 3alpha-hydroxy-ent-kaurene + flavin + H2O
|
1.14.14.70
ent-sandaracopimaradiene 3-hydroxylase
|
–
|
|
|
BRENDA:
BS429252
|
|
|
|
albendazole + reduced_flavodoxin + O2 <=> 4''-hydroxyalbendazole + flavin + H2O
|
1.14.14.74
albendazole monooxygenase (hydroxylating)
|
–
|
|
|
BRENDA:
BS442259
|
|
|
|
jasmonoyl-L-isoleucine + reduced_flavodoxin + O2 <=> 12-hydroxyjasmonoyl-L-isoleucine + flavin + H2O
|
1.14.14.48
jasmonoyl-L-amino acid 12-hydroxylase
1.14.14.49
12-hydroxyjasmonoyl-L-amino acid 12-hydroxylase
|
–
–
|
|
|
BRENDA:
BS440279
|
|
|
|
miltiradiene + reduced_flavodoxin + O2 <=> 11-oxomiltiradiene + flavin + H2O
|
1.14.14.175
ferruginol synthase
|
–
|
|
|
BRENDA:
BS443739
|
|
|
|
12-hydroxyjasmonoyl-L-isoleucine + reduced_flavodoxin + O2 <=> 12-hydroxy-12-oxojasmonoyl-L-isoleucine + flavin + H2O
|
1.14.14.49
12-hydroxyjasmonoyl-L-amino acid 12-hydroxylase
|
–
|
|
|
BRENDA:
BS440068
|
|
|
|
(S)-norreticuline + reduced_flavodoxin + O2 <=> 1,2-dehydronorreticuline + flavin + 2 H2O
|
1.14.19.54
1,2-dehydroreticuline synthase
|
–
|
|
|
BRENDA:
BS442676
|
|
|
|
vitamin_K2 + reduced_flavodoxin + O2 <=> omega-hydroxymenaquinone-4 + flavin + H2O
|
1.14.14.78
phylloquinone omega-hydroxylase
|
–
|
|
|
BRENDA:
BS429307
|
|
|
|
3-Methoxybenzoate + reduced_flavodoxin + O2 <=> vanillic_acid + flavin + H2O
|
1.14.14.92
benzoate 4-monooxygenase
|
–
|
|
|
BRENDA:
BS289264
|
|
|
|
6-trans-12-epi-Leukotriene_B4 + reduced_flavodoxin + O2 <=> 20-hydroxy-leukotriene_B4 + flavin + H2O
|
1.14.14.94
leukotriene-B4 20-monooxygenase
|
–
|
|
|
BRENDA:
BS257968
|
|
|
|
testosterone + reduced_flavodoxin + O2 <=> 6beta-hydroxytestosterone + flavin + H2O
|
1.14.14.1
unspecific monooxygenase
|
–
|
|
|
BRENDA:
BS410361
|
|
|
|
ebastin + reduced_flavodoxin + O2 <=> hydroxyebastine + flavin + H2O
|
1.14.14.74
albendazole monooxygenase (hydroxylating)
|
–
|
|
|
BRENDA:
BS443499
|
|
|
|
farnesol + reduced_flavodoxin + O2 <=> 12-hydroxyfarnesol + flavin + H2O
|
1.14.14.83
geraniol 8-hydroxylase
|
–
|
|
|
BRENDA:
BS443554
|
|
|
|
geranylgeraniol + reduced_flavodoxin + O2 <=> 16-hydroxygeranylgeraniol + flavin + H2O
|
1.14.14.83
geraniol 8-hydroxylase
|
–
|
|
|
BRENDA:
BS443585
|
|
|
|
ent-16-alpha-hydroxy-kaurene + reduced_flavodoxin + O2 <=> 16alpha-hydroxy-ent-kauranoate + flavin + H2O
|
1.14.14.86
ent-kaurene monooxygenase
|
–
|
|
|
BRENDA:
BS442138
|
|
|
|
cis-9,10-epoxystearic_acid + reduced_flavodoxin + O2 <=> 18-hydroxy-cis-9,10-epoxystearic_acid + flavin + H2O
|
1.14.14.80
long-chain fatty acid omega-monooxygenase
|
–
|
|
|
BRENDA:
BS443298
|
|
|
|
trans-9,10-epoxystearate + reduced_flavodoxin + O2 <=> 18-hydroxy-trans-9,10-epoxystearic_acid + flavin + H2O
|
1.14.14.80
long-chain fatty acid omega-monooxygenase
|
–
|
|
|
BRENDA:
BS443942
|
|
|
|
syn-aphidicolene + 3 reduced_flavodoxin + 3 O2 <=> 3beta-hydroxy-syn-aphidicolene + 2alpha-hydroxysandaracopimaradiene + 3 flavin + 4 H2O
|
1.14.14.86
ent-kaurene monooxygenase
|
–
|
|
|
BRENDA:
BS443915
|
|
|
|
isopimara-8(14),15-diene + 3 reduced_flavodoxin + 3 O2 <=> 3beta-hydroxyisopimara-8,15-diene + 2alpha-hydroxysandaracopimaradiene + 3 flavin + 4 H2O
|
1.14.14.86
ent-kaurene monooxygenase
|
–
|
|
|
BRENDA:
BS443659
|
|
|
|
astemizole + reduced_flavodoxin + O2 <=> hydroxyastemizole + flavin + H2O
|
1.14.14.74
albendazole monooxygenase (hydroxylating)
|
–
|
|
|
BRENDA:
BS443071
|
|
|
|
terfenadine + reduced_flavodoxin + O2 <=> terfenadine_alcohol + flavin + H2O
|
1.14.14.74
albendazole monooxygenase (hydroxylating)
|
–
|
|
|
BRENDA:
BS443928
|
|
|
|
uvaol + reduced_flavodoxin + O2 <=> ursolic_aldehyde + flavin + H2O
|
1.14.14.126
beta-amyrin 28-monooxygenase
|
–
|
|
|
BRENDA:
BS442591
|
|
|
|
salicylate + reduced_flavodoxin + O2 <=> 2,4-Dihydroxybenzoate + flavin + H2O
|
1.14.14.92
benzoate 4-monooxygenase
|
–
|
|
|
BRENDA:
BS289259
|
|
|
|
9beta-pimara-7,15-diene + 3 reduced_flavodoxin + 3 O2 <=> 3beta-hydroxy-syn-pimaradiene + 2alpha-hydroxy-syn-pimaradiene + 3 flavin + 4 H2O
|
1.14.14.86
ent-kaurene monooxygenase
|
–
|
|
|
BRENDA:
BS443918
|
|
|
|
genistein + reduced_flavodoxin + O2 <=> 3'',8-dihydroxygenistein + flavin + H2O
|
1.14.14.1
unspecific monooxygenase
|
–
|
|
|
BRENDA:
BS443579
|
|
|
|
Leucocyanidin + reduced_flavodoxin + O2 <=> 3,4-cis-leucodelphinidin + flavin + H2O
|
1.14.14.81
flavanoid 3',5'-hydroxylase
|
–
|
|
|
BRENDA:
BS442458
|
|
|
|
9beta-pimara-7,15-diene + reduced_flavodoxin + O2 <=> 3beta-hydroxy-syn-pimaradiene + flavin + H2O
|
1.14.14.86
ent-kaurene monooxygenase
|
–
|
|
|
BRENDA:
BS443921
|
|
|
|
5-deoxyleucopelargonidin + reduced_flavodoxin + O2 <=> 5-deoxyleucocyanidin + flavin + H2O
|
1.14.14.82
flavonoid 3'-monooxygenase
|
–
|
|
|
BRENDA:
BS442960
|
|
|
|
eriodictyol + reduced_flavodoxin + O2 <=> 6-hydroxyeriodictyol + 8-hydroxyeriodictyol + flavin + H2O
|
1.14.14.1
unspecific monooxygenase
|
–
|
|
|
BRENDA:
BS443522
|
|
|
|
betulin + reduced_flavodoxin + O2 <=> betulinic_aldehyde + flavin + H2O
|
1.14.14.126
beta-amyrin 28-monooxygenase
|
–
|
|
|
BRENDA:
BS442339
|
|
|
|
maniladiol + reduced_flavodoxin + O2 <=> cochalic_acid + flavin + H2O
|
1.14.14.115
11-oxo-beta-amyrin 30-oxidase
1.14.14.126
beta-amyrin 28-monooxygenase
|
–
–
|
|
|
BRENDA:
BS442471
|
|
|
|
oleanolic_acid + reduced_flavodoxin + O2 <=> cochalic_acid + flavin + H2O
|
1.14.14.115
11-oxo-beta-amyrin 30-oxidase
1.14.14.126
beta-amyrin 28-monooxygenase
|
–
–
|
|
|
BRENDA:
BS442498
|
|
|
|
ent-cassa-12,15-diene + 3 reduced_flavodoxin + 3 O2 <=> ent-cassadien-19-oic_acid + 3 flavin + 4 H2O
|
1.14.14.86
ent-kaurene monooxygenase
|
–
|
|
|
BRENDA:
BS443509
|
|
|
|
ent-isokaurene + 3 reduced_flavodoxin + 3 O2 <=> ent-isokaur-16-en-19-oate + 3 flavin + 4 H2O
|
1.14.14.86
ent-kaurene monooxygenase
|
–
|
|
|
BRENDA:
BS443512
|
|
|
|
ent-isokaur-16-ene + reduced_flavodoxin + O2 <=> ent-isokaur-16-en-19-oate + flavin + H2O
|
1.14.14.86
ent-kaurene monooxygenase
|
–
|
|
|
BRENDA:
BS443511
|
|
|
|
ent-sandaracopimara-8(14),15-diene + 3 reduced_flavodoxin + 3 O2 <=> ent-sandaracopimaradien-19-oic_acid + 3 flavin + 4 H2O
|
1.14.14.86
ent-kaurene monooxygenase
|
–
|
|
|
BRENDA:
BS443514
|
|
|
|
ent-trachylobane + 3 reduced_flavodoxin + 3 O2 <=> ent-trachyloban-19-oic_acid + 3 flavin + 4 H2O
|
1.14.14.86
ent-kaurene monooxygenase
|
–
|
|
|
BRENDA:
BS443517
|
|
|
|
(S)-scoulerine + reduced_flavodoxin + O2 <=> nandinine + flavin + 2 H2O
|
1.14.19.64
(S)-stylopine synthase
|
–
|
|
|
BRENDA:
BS442680
|
|
|
|
8-methoxypsoralen + reduced_flavodoxin + O2 <=> 5-hydroxy-8-methoxypsoralen + flavin + H2O
|
1.14.14.164
fraxetin 5-hydroxylase
1.14.14.165
indole-3-carbonyl nitrile 4-hydroxylase
|
–
–
|
|
|
BRENDA:
BS444846
|
|
|
|
H2O + O2 + reduced_flavodoxin + H+ <=> 1alpha,25-dihydroxyvitamin_D3 + flavin + H2O
|
1.14.14.24
vitamin D 25-hydroxylase
|
–
|
|
|
BRENDA:
BS418211
|
|
|
|
jasmonoyl-L-leucine + reduced_flavodoxin + O2 <=> 12-hydroxyjasmonoyl-L-leucine + flavin + H2O
|
1.14.14.48
jasmonoyl-L-amino acid 12-hydroxylase
|
–
|
|
|
BRENDA:
BS441488
|
|
|
|
jasmonoyl-L-phenylalanine + reduced_flavodoxin + O2 <=> 12-hydroxyjasmonoyl-L-phenylalanine + flavin + H2O
|
1.14.14.48
jasmonoyl-L-amino acid 12-hydroxylase
|
–
|
|
|
BRENDA:
BS441489
|
|
|
|
jasmonoyl-L-valine + reduced_flavodoxin + O2 <=> 12-hydroxyjasmonoyl-L-valine + flavin + H2O
|
1.14.14.48
jasmonoyl-L-amino acid 12-hydroxylase
|
–
|
|
|
BRENDA:
BS441491
|
|
|
|
daidzein + reduced_flavodoxin + O2 <=> 3''-hydroxydaidzein + flavin + H2O
|
1.14.14.1
unspecific monooxygenase
|
–
|
|
|
BRENDA:
BS443442
|
|
|
|
(Z)-phenylacetaldoxime + reduced_flavodoxin + O2 <=> phenylacetonitrile + flavin + 2 H2O
|
1.14.14.41
(E)-2-methylbutanal oxime monooxygenase
|
–
|
|
|
BRENDA:
BS439762
|
|
|
|
isopimara-7,15-dienol + reduced_flavodoxin + O2 <=> isopimaradienal + flavin + H2O
|
1.14.14.145
abieta-7,13-dien-18-ol hydroxylase
|
–
|
|
|
BRENDA:
BS388948
|
|
|
|
9beta-pimara-7,15-diene + reduced_flavodoxin + O2 <=> 3beta-hydroxy-9beta-pimara-7,15-diene-19,6beta-olide + flavin + H2O
|
1.14.14.111
9beta-pimara-7,15-diene oxidase
|
–
|
|
|
BRENDA:
BS418344
|
|
|
|
ursolic_aldehyde + reduced_flavodoxin + O2 <=> ursolic_acid + flavin + H2O
|
1.14.14.126
beta-amyrin 28-monooxygenase
|
–
|
|
|
BRENDA:
BS442589
|
|
|
|
alpha-amyrin + reduced_flavodoxin + O2 <=> ursolic_acid + flavin + H2O
|
1.14.14.126
beta-amyrin 28-monooxygenase
|
–
|
|
|
BRENDA:
BS430873
|
|
|
|
(E)-phenylacetaldoxime + reduced_flavodoxin + O2 <=> (S)-mandelonitrile + flavin + 2 H2O
|
1.14.14.37
4-hydroxyphenylacetaldehyde oxime monooxygenase
|
–
|
|
|
BRENDA:
BS436644
|
|
|
|
11-deoxycorticosterone + reduced_flavodoxin + O2 <=> 15beta-hydroxy-11-deoxycorticosterone + flavin + H2O
|
1.14.15.8
steroid 15beta-monooxygenase
|
–
|
|
|
BRENDA:
BS404982
|
|
|
|
naringenin + reduced_flavodoxin + O2 <=> eriodictyol + 6-hydroxyeriodictyol + 8-hydroxyeriodictyol + flavin + H2O
|
1.14.14.1
unspecific monooxygenase
|
–
|
|
|
BRENDA:
BS443792
|
|
|
|
reduced_flavodoxin + nitroblue_tetrazolium <=> flavin + nitroblue_tetrazolium
|
1.5.5.1
electron-transferring-flavoprotein dehydrogenase
|
–
|
|
|
BRENDA:
BS259367
|
|
|
|
a_(7R,8R)-7,8-dihydroxy-long-chain-acyl-[acyl-carrier_protein] + reduced_flavodoxin + O2 <=> a_7-oxoheptanoyl-[acyl-carrier_protein] + an_n-alkanal + flavin + 2 H2O
|
1.14.14.46
pimeloyl-[acyl-carrier protein] synthase
|
–
|
|
|
BRENDA:
BR50376
|
|
|
|
acenaphthene + reduced_flavodoxin + O2 <=> 1-Acenaphthenol + flavin + H2O
|
1.14.14.1
unspecific monooxygenase
|
–
|
|
|
BRENDA:
BS387709
|
|
|
|
(+)-limonene + reduced_flavodoxin + O2 <=> (+)-trans-Isopiperitenol + flavin + H2O
|
1.14.14.99
(S)-limonene 3-monooxygenase
|
–
|
|
|
BRENDA:
BS257976
|
|
|
|
(-)-limonene + reduced_flavodoxin + O2 <=> (+)-trans-Isopiperitenol + flavin + H2O
|
1.14.14.99
(S)-limonene 3-monooxygenase
|
–
|
|
|
BRENDA:
BS374951
|
|
|
|
reduced_flavodoxin + 6-heptylubiquinone <=> flavin + 2,3-Dimethoxy-5-methyl-6-decyl-1,4-benzoquinol
|
1.5.5.1
electron-transferring-flavoprotein dehydrogenase
|
–
|
|
|
BRENDA:
BS259372
|
|
|
|
2-methylpentanoyl-CoA + flavin <=> 2-methyl-2-pentenoyl-CoA + reduced_flavodoxin + H+
|
1.3.8.5
2-methyl-branched-chain-enoyl-CoA reductase
|
–
|
|
|
BRENDA:
BS5942
|
|
|
|
apigenin + reduced_flavodoxin + O2 <=> 5,7,3'',4'',5''-pentahydroxyflavone + flavin + H2O
|
1.14.14.81
flavanoid 3',5'-hydroxylase
|
–
|
|
|
BRENDA:
BS387875
|
|
|
|
cis-N-methylcanadine + reduced_flavodoxin + O2 <=> Allocryptopine + flavin + H2O
|
1.14.14.97
methyltetrahydroprotoberberine 14-monooxygenase
|
–
|
|
|
BRENDA:
BS186709
|
|
|
|
arachidoyl-CoA + flavin <=> (2E)-eicosenoyl-CoA + reduced_flavodoxin
|
1.3.8.8
long-chain acyl-CoA dehydrogenase
|
–
|
|
|
BRENDA:
BS260357
|
|
|
|
benzoate + reduced_flavodoxin + O2 <=> 2-hydro-1,2-dihydroxybenzoate + flavin + H2O
|
1.14.14.92
benzoate 4-monooxygenase
|
–
|
|
|
BRENDA:
BS402500
|
|
|
|
(3S)-(E,E)-geranyllinalool + reduced_flavodoxin + O2 <=> (E,E)-4,8,12-trimethyltrideca-1,3,7,11-tetraene + 3-buten-2-one + flavin + 2 H2O
|
1.14.14.58
trimethyltridecatetraene synthase
|
–
|
|
|
BRENDA:
BS413147
|
|
|
|
erythrodiol + reduced_flavodoxin + O2 <=> oleanolic_acid + flavin + H2O
|
1.14.14.126
beta-amyrin 28-monooxygenase
|
–
|
|
|
BRENDA:
BS442404
|
|
|
|
laurate + reduced_flavodoxin + O2 <=> 12-hydroxydodecanoate + flavin + H2O
|
1.14.14.130
laurate 7-monooxygenase
1.14.14.80
long-chain fatty acid omega-monooxygenase
1.14.15.3
alkane 1-monooxygenase
|
–
–
–
|
|
|
BRENDA:
BS389083
|
|
|
|
thioanisole + reduced_flavodoxin + O2 <=> (R)-methyl_phenyl_sulfoxide + flavin + H2O
|
1.14.14.1
unspecific monooxygenase
|
–
|
|
|
BRENDA:
BS415126
|
|
|
|
5beta-cholestan-3alpha,7alpha-diol + reduced_flavodoxin + O2 <=> 5beta-cholestane-3alpha,7alpha,12alpha-triol + flavin + H2O
|
1.14.14.139
5beta-cholestane-3alpha,7alpha-diol 12alpha-hydroxylase
|
–
|
|
|
BRENDA:
BS394668
|
|
|
|
reduced_flavodoxin + 2,6-dichlorophenolindophenol <=> flavin + reduced_2,6-dichlorophenolindophenol
|
1.5.5.1
electron-transferring-flavoprotein dehydrogenase
|
–
|
|
|
BRENDA:
BS441948
|
|
|
|
naringenin + reduced_flavodoxin + O2 <=> 2-hydroxynaringenin + flavin + H2O
|
1.14.14.162
flavanone 2-hydroxylase
|
–
|
|
|
BRENDA:
BS371271
|
|
|
|
allopregnanolone + reduced_flavodoxin + O2 <=> 5alpha-pregnan-3alpha,17alpha-diol-20-one + flavin + H2O
|
1.14.14.32
17alpha-hydroxyprogesterone deacetylase
|
–
|
|
|
BRENDA:
BS432636
|
|
|
|
ferulic_acid + reduced_flavodoxin + O2 <=> 5-hydroxyferulic_acid + flavin + H2O
|
1.14.14.B13
|
–
|
|
|
BRENDA:
BS441391
|
|
|
|
coniferyl_aldehyde + reduced_flavodoxin + O2 <=> 5-hydroxyconiferaldehyde + flavin + H2O
|
1.14.14.B13
|
–
|
B
|
|
BRENDA:
BR52337
|
|
|
|
macrolide_YC-17 + reduced_flavodoxin + O2 <=> methymycin + flavin + H2O
|
1.14.14.1
unspecific monooxygenase
|
–
|
|
|
BRENDA:
BS386563
|
|
|
|
macrolide_YC-17 + reduced_flavodoxin + O2 <=> neomethymycin + flavin + H2O
|
1.14.14.1
unspecific monooxygenase
|
–
|
|
|
BRENDA:
BS386564
|
|
|
|
macrolide_YC-17 + reduced_flavodoxin + O2 <=> novamethymycin + flavin + H2O
|
1.14.14.1
unspecific monooxygenase
|
–
|
|
|
BRENDA:
BS386565
|
|
|
|
narbomycin + reduced_flavodoxin + O2 <=> pikromycin + flavin + H2O
|
1.14.14.1
unspecific monooxygenase
|
–
|
|
|
BRENDA:
BS386605
|
|
|
|
beta-ionone + reduced_flavodoxin + O2 <=> 4-hydroxy-beta-ionone + flavin + H2O
|
1.14.14.1
unspecific monooxygenase
|
–
|
|
|
BRENDA:
BS388219
|
|
|
|
oleoyl-CoA + flavin <=> 2,9-octadecadienoyl-CoA + reduced_flavodoxin
|
1.3.8.8
long-chain acyl-CoA dehydrogenase
|
–
|
|
|
BRENDA:
BS398013
|
|
|
|
9beta-pimara-7,15-diene + reduced_flavodoxin + O2 <=> momilactone_A + flavin + H2O
|
1.14.14.123
oryzalexin D synthase
|
–
|
|
|
BRENDA:
BS430725
|
|
|
|
progesterone + reduced_flavodoxin + O2 <=> 16alpha-hydroxyprogesterone + flavin + H2O
|
1.14.14.16
steroid 21-monooxygenase
1.14.14.19
steroid 17alpha-monooxygenase
1.14.14.32
17alpha-hydroxyprogesterone deacetylase
|
–
–
–
|
|
|
BRENDA:
BS428887
|
|
|
|
chenodeoxycholic_acid + reduced_flavodoxin + O2 <=> hyodeoxycholic_acid + flavin + H2O
|
1.14.14.57
taurochenodeoxycholate 6alpha-hydroxylase
|
–
|
|
|
BRENDA:
BS443284
|
|
|
|
betulinic_aldehyde + reduced_flavodoxin + O2 <=> betulinic_acid + flavin + H2O
|
1.14.14.126
beta-amyrin 28-monooxygenase
|
–
|
|
|
BRENDA:
BS442341
|
|
|
|
lupeol + reduced_flavodoxin + O2 <=> betulinic_acid + flavin + H2O
|
1.14.14.126
beta-amyrin 28-monooxygenase
|
–
|
|
|
BRENDA:
BS431057
|
|
|
|
4-Hydroxyphenylacetonitrile + reduced_flavodoxin + O2 <=> (R)-4-hydroxymandelonitrile + flavin + H2O
|
1.14.14.77
phenylacetonitrile alpha-monooxygenase
|
–
|
|
|
BRENDA:
BS442208
|
|
|
|
1-nitro-2-(4-hydroxyphenyl)ethane + O2 + reduced_flavodoxin <=> N,N-dihydroxy-L-tyrosine + flavin + H2O
|
1.14.14.36
tyrosine N-monooxygenase
|
–
|
|
|
BRENDA:
BS436700
|
|
|
|
5-hydroxymarmesin + reduced_flavodoxin + O2 <=> bergaptol + acetone + flavin + H2O
|
1.14.14.141
psoralen synthase
|
–
|
|
|
BRENDA:
BS387583
|
|
|
|
Undecanoate + reduced_flavodoxin + O2 <=> 11-Hydroxyundecanoate + flavin + H2O
|
1.14.14.80
long-chain fatty acid omega-monooxygenase
|
–
|
|
|
BRENDA:
BS434453
|
|
|
|
reduced_flavodoxin + 6-(10-bromodecyl)ubiquinone <=> flavin + 2,3-Dimethoxy-5-methyl-6-(10-bromodecyl)-1,4-benzoquinol
|
1.5.5.1
electron-transferring-flavoprotein dehydrogenase
|
–
|
|
|
BRENDA:
BS259374
|
|
|
|
propylbenzene + reduced_flavodoxin + O2 <=> (R)-1-phenylpropanol + (R)-1-phenylpropanol + propiophenone + flavin + H2O
|
1.14.14.1
unspecific monooxygenase
|
–
|
|
|
BRENDA:
BS428892
|
|
|
|
1,8-cineole + reduced_flavodoxin + O2 <=> 6-endo-hydroxycineole + flavin + H2O
|
1.14.14.133
1,8-cineole 2-endo-monooxygenase
|
–
|
|
|
BRENDA:
BR50102
|
|
|
|
(S)-N-methylcoclaurine + (R)-N-methylcoclaurine + (S)-Coclaurine + reduced_flavodoxin + O2 <=> Berbamunine + (R,R)-guattegaumerine + (R,S)-2''-norberbamunine + flavin + H2O
|
1.14.19.66
berbamunine synthase
|
–
|
|
|
BRENDA:
BS259655
|
|
|
|
2 (S)-N-methylcoclaurine + 2 (R)-N-methylcoclaurine + reduced_flavodoxin + O2 <=> Berbamunine + (R,R)-guattegaumerine + flavin + H2O
|
1.14.19.66
berbamunine synthase
|
–
|
|
|
BRENDA:
BS259654
|
|
|
|
ethylbenzene + reduced_flavodoxin + O2 <=> cis-1,2-dihydro-3-ethylcatechol + flavin + H2O
|
1.14.12.3
benzene 1,2-dioxygenase
|
–
|
|
|
BRENDA:
BS391939
|
|
|
|
p-hydroxyphenylacetaldoxime + reduced_flavodoxin + O2 <=> 4-hydroxymandelonitrile + flavin + 2 H2O
|
1.14.14.44
phenylacetaldehyde oxime monooxygenase
|
–
|
|
|
BRENDA:
BS438844
|
|
|
|
4-Hydroxyphenylacetonitrile + reduced_flavodoxin + O2 <=> 4-hydroxymandelonitrile + flavin + 2 H2O
|
1.14.14.44
phenylacetaldehyde oxime monooxygenase
|
–
|
|
|
BRENDA:
BS438845
|
|
|
|
(S)-cis-N-Methylcorydalmine + reduced_flavodoxin + O2 <=> muramine + flavin + H2O
|
1.14.14.97
methyltetrahydroprotoberberine 14-monooxygenase
|
–
|
|
|
BRENDA:
BS186713
|
|
|
|
(S)-cis-N-Methyltetrahydropalmitine + reduced_flavodoxin + O2 <=> muramine + flavin + H2O
|
1.14.14.97
methyltetrahydroprotoberberine 14-monooxygenase
|
–
|
|
|
BRENDA:
BS186712
|
|
|
|
prostaglandin_E1 + reduced_flavodoxin + O2 <=> 20-hydroxyprostaglandin_E1 + flavin + H2O
|
1.14.14.1
unspecific monooxygenase
|
–
|
|
|
BRENDA:
BS377557
|
|
|
|
naringenin + O2 + reduced_flavodoxin <=> genistein + 2 H2O + flavin
|
1.14.14.87
2-hydroxyisoflavanone synthase
|
–
|
|
|
BRENDA:
BS442645
|
|
|
|
reduced_flavodoxin + 2,3-dimethoxy-5-methyl-6-(3-methylbut-2-en)-1,4-benzoquinone <=> flavin + 2,3-dimethoxy-5-methyl-6-(3-methylbut-2-en)-1,4-benzoquinol
|
1.5.5.1
electron-transferring-flavoprotein dehydrogenase
|
–
|
|
|
BRENDA:
BS259366
|
|
|
|
reduced_flavodoxin + 2,3-dimethoxy-5-methyl-6-pentyl-1,4-benzoquinone <=> flavin + 2,3-dimethoxy-5-methyl-6-pentyl-1,4-benzoquinol
|
1.5.5.1
electron-transferring-flavoprotein dehydrogenase
|
–
|
|
|
BRENDA:
BS259368
|
|
|
|
reduced_flavodoxin + nonylubiquinone <=> flavin + nonylubiquinol
|
1.5.5.1
electron-transferring-flavoprotein dehydrogenase
|
–
|
|
|
BRENDA:
BS259370
|
|
|
|
octanoyl-CoA + flavin <=> 2-octenoyl-CoA + reduced_flavodoxin
|
1.3.8.7
medium-chain acyl-CoA dehydrogenase
1.3.8.8
long-chain acyl-CoA dehydrogenase
|
–
–
|
|
|
BRENDA:
BS260351
|
|
|
|
taxa-4(20),11-dien-5alpha-ol + reduced_flavodoxin + O2 <=> taxa-4(20),11-dien-5alpha,13alpha-diol + flavin + H2O
|
1.14.14.106
taxane 13alpha-hydroxylase
|
–
|
B
|
|
BRENDA:
BR40518
|
|
|
|
reduced_flavodoxin + ubiquinone-4 <=> flavin + ubiquinol-4
|
1.5.5.1
electron-transferring-flavoprotein dehydrogenase
|
–
|
|
|
BRENDA:
BS259377
|
|
|
|
7,4''-dihydroxyflavanone + 2 reduced_flavodoxin + 2 O2 <=> 2,7,4''-trihydroxyisoflavanone + 3,7,4''-trihydroxyflavanone + 2 flavin + 2 H2O
|
1.14.14.87
2-hydroxyisoflavanone synthase
|
–
|
|
|
BRENDA:
BS416462
|
|
|
|
hexanoyl-CoA + flavin <=> trans-2-hexenoyl-CoA + reduced_flavodoxin
|
1.3.8.4
isovaleryl-CoA dehydrogenase
1.3.8.7
medium-chain acyl-CoA dehydrogenase
1.3.8.8
long-chain acyl-CoA dehydrogenase
|
–
–
–
|
|
|
BRENDA:
BR36852
|
|
|
|
typhasterol + reduced_flavodoxin + O2 <=> 24-epicastasterone + flavin + H2O
|
1.14.14.147
3-epi-6-deoxocathasterone 23-monooxygenase
|
–
|
|
|
BRENDA:
BS427554
|
|
|
|
(S)-2-methylbutanoyl-CoA + flavin <=> tigloyl-CoA + reduced_flavodoxin
|
1.3.8.4
isovaleryl-CoA dehydrogenase
|
–
|
|
|
BRENDA:
BS425198
|
|
|
|
(S)-2-methylpentadecanoyl-CoA + flavin <=> 2-methyl-2-pentadecenoyl-CoA + reduced_flavodoxin
|
1.3.8.8
long-chain acyl-CoA dehydrogenase
|
–
|
|
|
BRENDA:
BS260359
|
|
|
|
3-hydroxycinnamic_acid + reduced_flavodoxin + O2 <=> caffeic_acid + flavin + H2O
|
1.14.14.91
trans-cinnamate 4-monooxygenase
|
–
|
|
|
BRENDA:
BS386814
|
|
|
|
5alpha-dihydroprogesterone + reduced_flavodoxin + O2 <=> 5alpha-pregnan-17alpha-ol-3,20-dione + flavin + H2O
|
1.14.14.32
17alpha-hydroxyprogesterone deacetylase
|
–
|
|
|
BRENDA:
BS432635
|
|
|
|
(24S)-24-hydroxycholesterol + reduced_flavodoxin + O2 <=> 24,25-dihydroxycholesterol + 24,27-dihydroxycholesterol + flavin + H2O
|
1.14.14.25
cholesterol 24-hydroxylase
|
–
|
|
|
BRENDA:
BS386802
|
|
|
|
(24S)-24-hydroxycholesterol + reduced_flavodoxin + O2 <=> 24,25-dihydroxycholesterol + flavin + H2O
|
1.14.14.25
cholesterol 24-hydroxylase
|
–
|
|
|
BRENDA:
BS375420
|
|
|
|
(24S)-24-hydroxycholesterol + reduced_flavodoxin + O2 <=> 24,27-dihydroxycholesterol + flavin + H2O
|
1.14.14.25
cholesterol 24-hydroxylase
|
–
|
|
|
BRENDA:
BS375421
|
|
|
|
m-methoxycinnamate + reduced_flavodoxin + O2 <=> ferulic_acid + flavin + H2O
|
1.14.14.91
trans-cinnamate 4-monooxygenase
|
–
|
|
|
BRENDA:
BS386815
|
|
|
|
myristoyl-CoA + flavin <=> tetradecenoyl-CoA + reduced_flavodoxin
|
1.3.8.7
medium-chain acyl-CoA dehydrogenase
|
–
|
|
|
BRENDA:
BS442021
|
|
|
|
myristoyl-CoA + flavin <=> 2-tetradecenoyl-CoA + reduced_flavodoxin
|
1.3.8.8
long-chain acyl-CoA dehydrogenase
|
–
|
|
|
BRENDA:
BS260354
|
|
|
|
7-ethoxy-4-trifluoromethylcoumarin + reduced_flavodoxin + O2 <=> 7-hydroxy-4-trifluoromethylcoumarin + flavin + H2O
|
1.14.14.1
unspecific monooxygenase
|
–
|
|
|
BRENDA:
BS414179
|
|
|
|
5alpha-pregnan-3alpha,17alpha-diol-20-one + reduced_flavodoxin + O2 <=> androsterone + flavin + H2O
|
1.14.14.32
17alpha-hydroxyprogesterone deacetylase
|
–
|
|
|
BRENDA:
BS432571
|
|
|
|
3-Fluorobenzoate + reduced_flavodoxin + O2 <=> 3-Fluoro-4-hydroxybenzoate + flavin + H2O
|
1.14.14.92
benzoate 4-monooxygenase
|
–
|
|
|
BRENDA:
BS289261
|
|
|
|
kaempferol + reduced_flavodoxin + O2 <=> myricetin + flavin + H2O
|
1.14.14.81
flavanoid 3',5'-hydroxylase
|
–
|
|
|
BRENDA:
BS443664
|
|
|
|
taxa-4(20),11(12)-diene + reduced_flavodoxin + O2 <=> taxa-4(20),11-dien-5alpha-ol + flavin + H2O
|
1.14.14.176
taxadiene 5alpha-hydroxylase
|
–
|
|
|
BRENDA:
BS377847
|
|
|
|
2,6-dimethylheptanoyl-CoA + flavin <=> 2,3-dehydro-2,6-dimethylheptanoyl-CoA + reduced_flavodoxin
|
1.3.8.8
long-chain acyl-CoA dehydrogenase
|
–
|
|
|
BRENDA:
BS413186
|
|
|
|
benzylamine + reduced_flavodoxin + O2 <=> benzylamine_N-oxide + flavin + H2O
|
1.14.13.8
flavin-containing monooxygenase
|
–
|
|
|
BRENDA:
BS386384
|
|
|
|
lanosterol + reduced_flavodoxin + O2 <=> 4,4-dimethylcholesta-8,14,24-trienol + flavin + H2O
|
1.14.14.154
sterol 14alpha-demethylase
|
–
|
|
|
BRENDA:
BS427474
|
|
|
|
methyl_p-tolyl_sulfide + reduced_flavodoxin + O2 <=> methyl_4-tolyl_sulfoxide + (R)-methyl_4-tolyl_sulfoxide + flavin + H2O
|
1.14.14.1
unspecific monooxygenase
|
–
|
|
|
BRENDA:
BS428787
|
|
|
|
methyl_p-tolyl_sulfide + reduced_flavodoxin + O2 <=> methyl_4-tolyl_sulfoxide + flavin + H2O
|
1.14.14.1
unspecific monooxygenase
|
–
|
|
|
BRENDA:
BS414138
|
|
|
|
taxa-4(20),11-dien-5alpha-yl_acetate + reduced_flavodoxin + O2 <=> taxa-4(20),11(12)-dien-5alpha-yl-acetyl-13alpha-ol + flavin + H2O
|
1.14.14.106
taxane 13alpha-hydroxylase
|
–
|
|
|
BRENDA:
BS386706
|
|
|
|
taxadien-5alpha-yl_acetate + reduced_flavodoxin + O2 <=> taxa-4(20),11(12)-dien-5alpha-yl-acetyl-13alpha-ol + flavin + H2O
|
1.14.14.106
taxane 13alpha-hydroxylase
|
–
|
|
|
BRENDA:
BS386707
|
|
|
|
scoulerine + reduced_flavodoxin + O2 <=> (S)-nandinine + flavin + H2O
|
1.14.19.64
(S)-stylopine synthase
|
–
|
|
|
BRENDA:
BS451379
|
|
|
|
averantin + reduced_flavodoxin + O2 <=> 5''-hydroxyaverantin + flavin + H2O
|
1.14.14.116
averantin hydroxylase
|
–
|
|
|
BRENDA:
BS421914
|
|
|
|
3-chlorobenzoate + reduced_flavodoxin + O2 <=> 3-Chloro-4-hydroxybenzoate + flavin + H2O
|
1.14.14.92
benzoate 4-monooxygenase
|
–
|
|
|
BRENDA:
BS289262
|
|
|
|
stearoyl-CoA + flavin <=> 2-octadecenoyl-CoA + reduced_flavodoxin
|
1.3.8.8
long-chain acyl-CoA dehydrogenase
|
–
|
|
|
BRENDA:
BS260356
|
|
|
|
decanoyl-CoA + flavin <=> trans-2-decenoyl-CoA + reduced_flavodoxin
|
1.3.8.7
medium-chain acyl-CoA dehydrogenase
1.3.8.8
long-chain acyl-CoA dehydrogenase
|
–
–
|
|
|
BRENDA:
BS260352
|
|
|
|
decanoyl-CoA + flavin <=> decenoyl-CoA + reduced_flavodoxin
|
1.3.8.7
medium-chain acyl-CoA dehydrogenase
|
–
|
|
|
BRENDA:
BS441271
|
|
|
|
coniferyl_alcohol + reduced_flavodoxin + O2 <=> 5-hydroxyconiferyl_alcohol + flavin + H2O
|
1.14.14.B13
|
–
|
|
|
BRENDA:
BS441212
|
|
|
|
luteolin + reduced_flavodoxin + O2 <=> 3'',8-dihydroxyapigenin + flavin + H2O
|
1.14.14.1
unspecific monooxygenase
|
–
|
|
|
BRENDA:
BS443719
|
|
|
|
apigenin + reduced_flavodoxin + O2 <=> 3'',8-dihydroxyapigenin + flavin + H2O
|
1.14.14.1
unspecific monooxygenase
|
–
|
|
|
BRENDA:
BS443058
|
|
|
|
naringenin + reduced_flavodoxin + O2 <=> eriodyctiol + flavin + H2O
|
1.14.14.82
flavonoid 3'-monooxygenase
|
–
|
|
|
BRENDA:
BS394928
|
|
|
|
alpha-amyrin + reduced_flavodoxin + O2 <=> uvaol + flavin + H2O
|
1.14.14.126
beta-amyrin 28-monooxygenase
|
–
|
|
|
BRENDA:
BS442266
|
|
|
|
reduced_cytochrome_c6 + flavin + hv <=> oxidized_cytochrome_c6 + reduced_flavodoxin
|
1.97.1.12
photosystem I
|
–
|
|
|
BRENDA:
BS442531
|
|
|
|
(1S)-cis-permethrin + O2 + reduced_flavodoxin <=> (3-phenoxyphenyl)methanol + 3-(4''-hydroxyphenoxy)-benzyl_alcohol + flavin
|
1.14.14.1
unspecific monooxygenase
|
–
|
|
|
BRENDA:
BS442639
|
|
|
|
(1S)-trans-permethrin + O2 + reduced_flavodoxin <=> (3-phenoxyphenyl)methanol + 3-(4''-hydroxyphenoxy)-benzyl_alcohol + flavin
|
1.14.14.1
unspecific monooxygenase
|
–
|
|
|
BRENDA:
BS442640
|
|
|
|
trans-permethrin + O2 + reduced_flavodoxin <=> (3-phenoxyphenyl)methanol + 3-(4''-hydroxyphenoxy)-benzyl_alcohol + flavin
|
1.14.14.1
unspecific monooxygenase
|
–
|
|
|
BRENDA:
BS442637
|
|
|
|
(1RS)-cis-permethrin + O2 + reduced_flavodoxin <=> (3-phenoxyphenyl)methanol + 3-(4''-hydroxyphenoxy)-benzyl_alcohol + flavin
|
1.14.14.1
unspecific monooxygenase
|
–
|
|
|
BRENDA:
BS442636
|
|
|
|
(S)-coreximine + reduced_flavodoxin + O2 <=> (S)-cheilanthifoline + flavin + H2O
|
1.14.19.64
(S)-stylopine synthase
1.14.19.65
(S)-cheilanthifoline synthase
|
–
–
|
|
|
BRENDA:
BS413766
|
|
|
|
(R,S)-cheilanthifoline + reduced_flavodoxin + O2 <=> (S)-Stylopine + flavin + H2O
|
1.14.19.64
(S)-stylopine synthase
|
–
|
|
|
BRENDA:
BS395151
|
|
|
|
2-fluorocinnamic_acid + reduced_flavodoxin + O2 <=> (E)-2-fluoro-4-hydroxycinnamate + flavin + H2O
|
1.14.14.91
trans-cinnamate 4-monooxygenase
|
–
|
|
|
BRENDA:
BS386807
|
|
|
|
3-hydroxyindolin-2-one + reduced_flavodoxin + O2 <=> 2,4-dihydroxy-2H-1,4-benzoxazin-3(4H)-one + flavin + H2O
|
1.14.14.110
2-hydroxy-1,4-benzoxazin-3-one monooxygenase
|
–
|
|
|
BRENDA:
BR49972
|
|
|
|
lauroyl-CoA + flavin <=> trans-2-dodecenoyl-CoA + reduced_flavodoxin
|
1.3.8.7
medium-chain acyl-CoA dehydrogenase
1.3.8.8
long-chain acyl-CoA dehydrogenase
|
–
–
|
|
|
BRENDA:
BS260353
|
|
|
|
3-Methoxybenzoate + reduced_flavodoxin + O2 <=> 3,4-dihydroxybenzoate + flavin + H2O
|
1.14.14.1
unspecific monooxygenase
|
–
|
|
|
BRENDA:
BS427979
|
|
|
|
benzoate + reduced_flavodoxin + O2 <=> 3,4-dihydroxybenzoate + flavin + H2O
|
1.14.14.1
unspecific monooxygenase
|
–
|
|
|
BRENDA:
BS428430
|
|
|
|
3-hydroxybenzoate + reduced_flavodoxin + O2 <=> 3,4-dihydroxybenzoate + flavin + H2O
|
1.14.13.23
3-hydroxybenzoate 4-monooxygenase
1.14.14.92
benzoate 4-monooxygenase
|
–
–
|
|
|
BRENDA:
BS288472
|
|
|
|
2-Fluorobenzoate + reduced_flavodoxin + O2 <=> 2-Fluoro-4-hydroxybenzoate + flavin + H2O
|
1.14.14.92
benzoate 4-monooxygenase
|
–
|
|
|
BRENDA:
BS289257
|
|
|
|
syn-stemoden-19-ol + reduced_flavodoxin + O2 <=> syn-stemoden-19-al + flavin + H2O
|
1.14.14.111
9beta-pimara-7,15-diene oxidase
|
–
|
|
|
BRENDA:
BS419126
|
|
|
|
syn-stemod-13(17)-ene + reduced_flavodoxin + O2 <=> syn-stemoden-19-ol + flavin + H2O
|
1.14.14.111
9beta-pimara-7,15-diene oxidase
|
–
|
|
|
BRENDA:
BS419124
|
|
|
|
a_(7S)-7-hydroxy-long-chain-acyl-[acyl-carrier_protein] + reduced_flavodoxin + O2 <=> a_(7R,8R)-7,8-dihydroxy-long-chain-acyl-[acyl-carrier_protein] + flavin + H2O
|
1.14.14.46
pimeloyl-[acyl-carrier protein] synthase
|
–
|
|
|
BRENDA:
BR50375
|
|
|
|
stearoyl-[acyl-carrier_protein] + reduced_flavodoxin + O2 <=> a_(7S)-7-hydroxy-long-chain-acyl-[acyl-carrier_protein] + flavin + H2O
|
1.14.14.46
pimeloyl-[acyl-carrier protein] synthase
|
–
|
|
|
BRENDA:
BR50374
|
|
|
|
cyclo(L-tyrosyl-L-tyrosyl) + reduced_flavodoxin + O2 <=> mycocyclosin + flavin + 2 H2O
|
1.14.19.70
mycocyclosin synthase
|
–
|
|
|
BRENDA:
BS442368
|
|
|
|
(-)-p-Menth-1-ene + reduced_flavodoxin + O2 <=> (-)-trans-Piperitol + flavin + H2O
|
1.14.14.99
(S)-limonene 3-monooxygenase
|
–
|
|
|
BRENDA:
BS257977
|
|
|
|
(+)-p-Menth-1-ene + reduced_flavodoxin + O2 <=> (+)-trans-Piperitol + flavin + H2O
|
1.14.14.99
(S)-limonene 3-monooxygenase
|
–
|
|
|
BRENDA:
BS257978
|
|
|
|
(-)-alpha-pinene + reduced_flavodoxin + O2 <=> 6,6-Dimethylbicyclo[3.1.1]hept-2-ene-2-methanol + flavin + H2O
|
1.14.14.1
unspecific monooxygenase
|
–
|
|
|
BRENDA:
BS399121
|
|
|
|
lupeol + 3 reduced_flavodoxin + 3 O2 <=> betulin + 3 flavin + 4 H2O
|
1.14.14.126
beta-amyrin 28-monooxygenase
|
–
|
|
|
BRENDA:
BS442467
|
|
|
|
(-)-kaurene + 3 reduced_flavodoxin + 3 O2 <=> ent-kaur-16-en-19-oate + 3 flavin + 4 H2O
|
1.14.14.86
ent-kaurene monooxygenase
|
–
|
|
|
BRENDA:
BS385998
|
|
|
|
Naphthalene + reduced_flavodoxin + O2 <=> 1-naphthol + H2O + flavin + H2O
|
1.14.14.1
unspecific monooxygenase
|
–
|
|
|
BRENDA:
BS389369
|
|
|
|
benzoxazin-3-one + reduced_flavodoxin + O2 <=> 2-hydroxy-2H-1,4-benzoxazin-3(4H)-one + flavin + H2O
|
1.14.14.157
indolin-2-one monooxygenase
|
–
|
|
|
BRENDA:
BS423057
|
|
|
|
tetradecanoyl-[acyl-carrier_protein] + reduced_flavodoxin + O2 <=> 11-hydroxytetradecanoyl-[acyl-carrier_protein] + 12-hydroxytetradecanoyl-[acyl-carrier_protein] + 14-hydroxytetradecanoyl-[acyl-carrier_protein] + flavin + H2O
|
1.14.14.46
pimeloyl-[acyl-carrier protein] synthase
|
–
|
|
|
BRENDA:
BS424110
|
|
|
|
palmitoyl-[acyl-carrier_protein] + reduced_flavodoxin + O2 <=> 11-hydroxyhexadecanoyl-[acyl-carrier_protein] + 12-hydroxyhexadecanoyl-[acyl-carrier_protein] + 13-hydroxytetradecanoyl-[acyl-carrier_protein] + 14-hydroxytetradecanoyl-[acyl-carrier_protein] + 15-hydroxytetradecanoyl-[acyl-carrier_protein] + flavin + H2O
|
1.14.14.46
pimeloyl-[acyl-carrier protein] synthase
|
–
|
|
|
BRENDA:
BS423669
|
|
|
|
liquiritigenin + O2 + reduced_flavodoxin <=> daidzein + 2 H2O + flavin
|
1.14.14.87
2-hydroxyisoflavanone synthase
|
–
|
|
|
BRENDA:
BS443714
|
|
|
|
(S)-cis-N-Methyltetrahydrothalifendine + reduced_flavodoxin + O2 <=> thalictrisine + flavin + H2O
|
1.14.14.97
methyltetrahydroprotoberberine 14-monooxygenase
|
–
|
|
|
BRENDA:
BS186711
|
|
|
|
coumaric_acid + reduced_flavodoxin + O2 <=> 2,4-dihydroxycinnamic_acid + flavin + H2O
|
1.14.14.91
trans-cinnamate 4-monooxygenase
|
–
|
|
|
BRENDA:
BS386808
|
|
|
|
prostaglandin_A1 + reduced_flavodoxin + O2 <=> 20-hydroxy-prostaglandin_A1 + flavin + H2O
|
1.14.14.1
unspecific monooxygenase
1.14.14.94
leukotriene-B4 20-monooxygenase
|
–
–
|
|
|
BRENDA:
BS257971
|
|
|
|
5-Deoxy-leukotriene_B4 + reduced_flavodoxin + O2 <=> 5-deoxy-20-hydroxy-leukotriene_B4 + flavin + H2O
|
1.14.14.94
leukotriene-B4 20-monooxygenase
|
–
|
|
|
BRENDA:
BS257969
|
|
|
|
5-epi-Leukotriene_B4 + reduced_flavodoxin + O2 <=> 5-epi-20-hydroxy-leukotriene_B4 + flavin + H2O
|
1.14.14.94
leukotriene-B4 20-monooxygenase
|
–
|
|
|
BRENDA:
BS257970
|
|
|
|
6-methyl-hex-5-en-2-ol + reduced_flavodoxin + O2 <=> 6-methyl-hex-5-en-2-one + flavin + H2O
|
1.14.14.84
linalool 8-monooxygenase
|
–
|
|
|
BRENDA:
BS258001
|
|
|
|
arachidonic_acid + reduced_flavodoxin + O2 <=> 18-hydroxyarachidonic_acid + 14,15-epoxyeicosa-5,8,11-trienoic_acid + flavin + H2O
|
1.14.14.1
unspecific monooxygenase
|
–
|
|
|
BRENDA:
BS414293
|
|
|
|
arachidonic_acid + reduced_flavodoxin + O2 <=> 18-hydroxyarachidonic_acid + 14,15-epoxyeicosa-5,8,11-trienoic_acid + 11,12-epoxyeicosatrienoic_acid + flavin + H2O
|
1.14.14.1
unspecific monooxygenase
|
–
|
|
|
BRENDA:
BS414292
|
|
|
|
(+)-Camphor + reduced_flavodoxin + O2 <=> (+)-exo-5-hydroxycamphor + flavin + H2O
|
1.14.14.1
unspecific monooxygenase
|
–
|
|
|
BRENDA:
BS407460
|
|
|
|
ethyl_phenyl_sulfide + reduced_flavodoxin + O2 <=> (R)-ethyl_phenyl_sulfoxide + ethyl_phenyl_sulfone + flavin + H2O
|
1.14.14.1
unspecific monooxygenase
|
–
|
|
|
BRENDA:
BS428609
|
|
|
|
2-Methylbenzoate + reduced_flavodoxin + O2 <=> 2-methyl-4-hydroxybenzoate + flavin + H2O
|
1.14.14.92
benzoate 4-monooxygenase
|
–
|
|
|
BRENDA:
BS289260
|
|
|
|
camphane + reduced_flavodoxin + O2 <=> camphor + flavin + H2O
|
1.14.14.133
1,8-cineole 2-endo-monooxygenase
|
–
|
|
|
BRENDA:
BS418532
|
|
|
|
3-methylbenzoate + reduced_flavodoxin + O2 <=> 4-hydroxy-3-methylbenzoate + flavin + H2O
|
1.14.14.92
benzoate 4-monooxygenase
|
–
|
|
|
BRENDA:
BS289263
|
|
|
|
reduced_flavodoxin + 6-(10-hydroxydecyl)ubiquinone <=> flavin + 6-(10-hydroxydecyl)ubiquinol
|
1.5.5.1
electron-transferring-flavoprotein dehydrogenase
|
–
|
|
|
BRENDA:
BS259371
|
|
|
|
protopine + reduced_flavodoxin + O2 <=> Dihydrosanguinarine + flavin + H2O
|
1.14.14.98
protopine 6-monooxygenase
|
–
|
|
|
BRENDA:
BS3067
|
|
|
|
1-methoxy-4-(methylsulfanyl)benzene + reduced_flavodoxin + O2 <=> p-methoxyphenyl_methyl_sulfoxide + flavin + H2O
|
1.14.14.1
unspecific monooxygenase
|
–
|
|
|
BRENDA:
BS414115
|
|
|
|
taxa-4(20),11-dien-5alpha-yl_acetate + reduced_flavodoxin + O2 <=> taxa-4(20),11-dien-5alpha,13alpha-diol-5-acetate + flavin + H2O
|
1.14.14.106
taxane 13alpha-hydroxylase
|
–
|
|
|
BRENDA:
BS289250
|
|
|
|
S-(L-prolyl)-[peptidyl-carrier_protein_PigG] + flavin <=> S-(1H-pyrrole-2-carbonyl)-[peptidyl-carrier_protein_PigG] + reduced_flavodoxin
|
1.3.8.14
L-prolyl-[peptidyl-carrier protein] dehydrogenase
|
–
|
|
|
BRENDA:
BS442541
|
|
|
|
S-(L-prolyl)-[peptidyl-carrier_protein] + flavin <=> S-(1H-pyrrole-2-carbonyl)-[peptidyl-carrier_protein] + reduced_flavodoxin
|
1.3.8.14
L-prolyl-[peptidyl-carrier protein] dehydrogenase
|
–
|
|
|
BRENDA:
BS442542
|
|
|
|
behenoyl-CoA + flavin <=> 2-docosenoyl-CoA + reduced_flavodoxin
|
1.3.8.8
long-chain acyl-CoA dehydrogenase
|
–
|
|
|
BRENDA:
BS260358
|
|
|
|
behenoyl-CoA + flavin <=> a_very-long-chain_trans-2,3-dehydroacyl-CoA + reduced_flavodoxin
|
1.3.8.9
very-long-chain acyl-CoA dehydrogenase
|
–
|
|
|
BRENDA:
BR50096
|
|
|
|
fluorene + reduced_flavodoxin + O2 <=> 9-fluorenol + flavin + H2O
|
1.14.14.1
unspecific monooxygenase
|
–
|
|
|
BRENDA:
BS388695
|
|
|
|
catechin + reduced_flavodoxin + O2 <=> gallocatechin + flavin + H2O
|
1.14.14.81
flavanoid 3',5'-hydroxylase
|
–
|
|
|
BRENDA:
BS442156
|
|
|
|
ethylbenzene + reduced_flavodoxin + O2 <=> (R)-1-phenylethanol + acetophenone + flavin + H2O
|
1.14.14.1
unspecific monooxygenase
|
–
|
|
|
BRENDA:
BS428611
|
|
|
|
Arachidonoyl-CoA + flavin <=> (2E,5Z,8Z,11Z,14Z)-2,5,8,11,14-eicosapentaenoyl-CoA + reduced_flavodoxin
|
1.3.8.8
long-chain acyl-CoA dehydrogenase
|
–
|
|
|
BRENDA:
BS396430
|
|
|
|
(R/S)-2-methylpalmitoyl-CoA + flavin <=> 2,3-dehydro-2-methylpalmitoyl-CoA + reduced_flavodoxin
|
1.3.8.8
long-chain acyl-CoA dehydrogenase
|
–
|
|
|
BRENDA:
BS260360
|
|
|
|
3-Methoxybenzoate + reduced_flavodoxin + O2 <=> 3-hydroxybenzoate + flavin + H2O
|
1.14.14.1
unspecific monooxygenase
|
–
|
|
|
BRENDA:
BS427980
|
|
|
|
reduced_flavodoxin + 2,5-dibromo-3-methyl-6-isopropylbenzoquinone <=> flavin + 2,5-dibromo-3-methyl-6-isopropyl-4-benzoquinol
|
1.5.5.1
electron-transferring-flavoprotein dehydrogenase
|
–
|
|
|
BRENDA:
BS374542
|
|
|
|
reduced_flavodoxin + 6-bis(isoprenyl)ubiquinone <=> flavin + 6-bis(isoprenyl)ubiquinol
|
1.5.5.1
electron-transferring-flavoprotein dehydrogenase
|
–
|
|
|
BRENDA:
BS374543
|
|
|
|
reduced_flavodoxin + 6-(10-bromodecyl)ubiquinone <=> flavin + bromodecylubiquinol
|
1.5.5.1
electron-transferring-flavoprotein dehydrogenase
|
–
|
|
|
BRENDA:
BS374545
|
|
|
|
reduced_flavodoxin + heptylubiquinone <=> flavin + heptylubiquinol
|
1.5.5.1
electron-transferring-flavoprotein dehydrogenase
|
–
|
|
|
BRENDA:
BS374548
|
|
|
|
reduced_flavodoxin + 6-(10-hydroxydecyl)ubiquinone <=> flavin + hydroxydecylubiquinol
|
1.5.5.1
electron-transferring-flavoprotein dehydrogenase
|
–
|
|
|
BRENDA:
BS374549
|
|
|
|
reduced_flavodoxin + pentadecylubiquinone <=> flavin + pentadecylubiquinol
|
1.5.5.1
electron-transferring-flavoprotein dehydrogenase
|
–
|
|
|
BRENDA:
BS374552
|
|
|
|
reduced_flavodoxin + tridecylubiquinone <=> flavin + tridecylubiquinol
|
1.5.5.1
electron-transferring-flavoprotein dehydrogenase
|
–
|
|
|
BRENDA:
BS374553
|
|
|
|
arachidonic_acid + reduced_flavodoxin + O2 <=> (18(R),5Z,8Z,11Z,14Z)-18-hydroxyeicosa-5,8,11,14-tetraenoic_acid + flavin + H2O
|
1.14.14.94
leukotriene-B4 20-monooxygenase
|
–
|
|
|
BRENDA:
BS376300
|
|
|
|
p-xylene + O2 + reduced_flavodoxin <=> 2,5-xylenol + H2O + flavin
|
1.14.14.1
unspecific monooxygenase
|
–
|
|
|
BRENDA:
BS443832
|
|
|
|
Prostaglandin + reduced_flavodoxin + O2 <=> 20-hydroxy-prostaglandin + flavin + H2O
|
1.14.14.1
unspecific monooxygenase
|
–
|
|
|
BRENDA:
BS375254
|
|
|
|
2''-hydroxyformononetin + reduced_flavodoxin + O2 <=> 2'',3''-dihydroxyformononetin + flavin + H2O
|
1.14.14.88
isoflavone 3'-hydroxylase
|
–
|
|
|
BRENDA:
BS375598
|
|
|
|
3''-hydroxyformononetin + reduced_flavodoxin + O2 <=> 2'',3''-dihydroxyformononetin + flavin + H2O
|
1.14.14.90
isoflavone 2'-hydroxylase
|
–
|
|
|
BRENDA:
BS375740
|
|
|
|
chlortetracycline + reduced_flavodoxin + O2 <=> 11a-hydroxy-chlortetracycline + flavin + H2O
|
1.14.13.231
tetracycline 11a-monooxygenase
|
–
|
|
|
BRENDA:
BS376474
|
|
|
|
demeclocycline + reduced_flavodoxin + O2 <=> 11a-hydroxy-demeclocycline + flavin + H2O
|
1.14.13.231
tetracycline 11a-monooxygenase
|
–
|
|
|
BRENDA:
BS376667
|
|
|
|
doxycycline + reduced_flavodoxin + O2 <=> 11a-hydroxy-doxycycline + flavin + H2O
|
1.14.13.231
tetracycline 11a-monooxygenase
|
–
|
|
|
BRENDA:
BS376752
|
|
|
|
minocycline + reduced_flavodoxin + O2 <=> 11a-hydroxy-minocycline + flavin + H2O
|
1.14.13.231
tetracycline 11a-monooxygenase
|
–
|
|
|
BRENDA:
BS377170
|
|
|
|
Prostaglandin_A2 + reduced_flavodoxin + O2 <=> 20-hydroxy-prostaglandin_A2 + flavin + H2O
|
1.14.14.1
unspecific monooxygenase
|
–
|
|
|
BRENDA:
BS377555
|
|
|
|
Prostaglandin_D2 + reduced_flavodoxin + O2 <=> 20-hydroxy-prostaglandin_D2 + flavin + H2O
|
1.14.14.1
unspecific monooxygenase
|
–
|
|
|
BRENDA:
BS377556
|
|
|
|
prostaglandin_E2 + reduced_flavodoxin + O2 <=> 20-hydroxy-prostaglandin_E2 + flavin + H2O
|
1.14.14.1
unspecific monooxygenase
|
–
|
|
|
BRENDA:
BS377558
|
|
|
|
prostaglandin_F2alpha + reduced_flavodoxin + O2 <=> 20-hydroxy-prostaglandin_F2alpha + flavin + H2O
|
1.14.14.1
unspecific monooxygenase
|
–
|
|
|
BRENDA:
BS377559
|
|
|
|
Prostaglandin_H1 + reduced_flavodoxin + O2 <=> 19-hydroxy-prostaglandin_H1 + flavin + H2O
|
1.14.14.94
leukotriene-B4 20-monooxygenase
|
–
|
|
|
BRENDA:
BS377560
|
|
|
|
prostaglandin_H2 + reduced_flavodoxin + O2 <=> 19-hydroxy-prostaglandin_H1 + flavin + H2O
|
1.14.14.94
leukotriene-B4 20-monooxygenase
|
–
|
|
|
BRENDA:
BS377561
|
|
|
|
simvastatin + reduced_flavodoxin + O2 <=> 6-beta-hydroxy-methyl-simvastatin + flavin + H2O
|
1.14.14.1
unspecific monooxygenase
|
–
|
|
|
BRENDA:
BS377769
|
|
|
|
vitamin_D2 + O2 + reduced_flavodoxin <=> 25-hydroxyvitamin_D2 + flavin + H2O
|
1.14.14.24
vitamin D 25-hydroxylase
|
–
|
|
|
BRENDA:
BS434624
|
|
|
|
linoleoyl-CoA + flavin <=> 2,9,12-octadecatrienoyl-CoA + reduced_flavodoxin
|
1.3.8.8
long-chain acyl-CoA dehydrogenase
|
–
|
|
|
BRENDA:
BS397703
|
|
|
|
(Z)-4-hydroxyphenylacetaldehyde_oxime + reduced_flavodoxin + O2 <=> 4-Hydroxyphenylacetonitrile + flavin + 2 H2O
|
1.14.14.41
(E)-2-methylbutanal oxime monooxygenase
|
–
|
|
|
BRENDA:
BS439761
|
|
|
|
palmitoyl-CoA + reduced_flavodoxin + O2 <=> 16-hydroxypalmitoyl-CoA + flavin + H2O
|
1.14.14.129
long-chain acyl-CoA omega-monooxygenase
|
–
|
|
|
BRENDA:
BS434115
|
|
|
|
5,7,3'',4''-tetrahydroxyflavanone + reduced_flavodoxin + O2 <=> 5,7,3'',4'',5''-pentahydroxyflavanone + flavin + H2O
|
1.14.14.81
flavanoid 3',5'-hydroxylase
|
–
|
|
|
BRENDA:
BS372121
|
|
|
|
(Z)-3-methylbutanaloxime + reduced_flavodoxin + O2 <=> 2-Hydroxy-3-methylbutyronitrile + flavin + 2 H2O
|
1.14.14.37
4-hydroxyphenylacetaldehyde oxime monooxygenase
|
–
|
|
|
BRENDA:
BS374964
|
|
|
|
(2E)-3-(3-chlorophenyl)prop-2-enoic_acid + reduced_flavodoxin + O2 <=> (2E)-3-(3-chloro-4-hydroxyphenyl)prop-2-enoic_acid + flavin + H2O
|
1.14.14.91
trans-cinnamate 4-monooxygenase
|
–
|
|
|
BRENDA:
BS386812
|
|
|
|
(2E)-3-(3-nitrophenyl)prop-2-enoic_acid + reduced_flavodoxin + O2 <=> (2E)-3-(4-hydroxy-3-nitrophenyl)prop-2-enoic_acid + flavin + H2O
|
1.14.14.91
trans-cinnamate 4-monooxygenase
|
–
|
|
|
BRENDA:
BS386817
|
|
|
|
(2E)-3-(2,3-dimethoxyphenyl)prop-2-enoic_acid + reduced_flavodoxin + O2 <=> (2E)-3-(4-hydroxy-2,3-dimethoxyphenyl)prop-2-enoic_acid + flavin + H2O
|
1.14.14.91
trans-cinnamate 4-monooxygenase
|
–
|
|
|
BRENDA:
BS386804
|
|
|
|
3-fluoro-trans-cinnamate + reduced_flavodoxin + O2 <=> (2E)-3-(3-fluoro-4-hydroxyphenyl)prop-2-enoic_acid + flavin + H2O
|
1.14.14.91
trans-cinnamate 4-monooxygenase
|
–
|
|
|
BRENDA:
BS386813
|
|
|
|
(2E)-3-(3-methylphenyl)prop-2-enoic_acid + reduced_flavodoxin + O2 <=> (2E)-3-(4-hydroxy-3-methylphenyl)prop-2-enoic_acid + flavin + H2O
|
1.14.14.91
trans-cinnamate 4-monooxygenase
|
–
|
|
|
BRENDA:
BS386816
|
|
|
|
2-chlorocinnamic_acid + reduced_flavodoxin + O2 <=> (2E)-3-(2-chloro-4-hydroxyphenyl)prop-2-enoic_acid + flavin + H2O
|
1.14.14.91
trans-cinnamate 4-monooxygenase
|
–
|
|
|
BRENDA:
BS386805
|
|
|
|
(2E)-3-(2-nitrophenyl)prop-2-enoic_acid + reduced_flavodoxin + O2 <=> (2E)-3-(4-hydroxy-2-nitrophenyl)prop-2-enoic_acid + flavin + H2O
|
1.14.14.91
trans-cinnamate 4-monooxygenase
|
–
|
|
|
BRENDA:
BS386811
|
|
|
|
2-methylcinnamic_acid + reduced_flavodoxin + O2 <=> (2E)-3-(4-hydroxy-2-methylphenyl)prop-2-enoic_acid + flavin + H2O
|
1.14.14.91
trans-cinnamate 4-monooxygenase
|
–
|
|
|
BRENDA:
BS386810
|
|
|
|
2-methoxycinnamate + reduced_flavodoxin + O2 <=> (2E)-3-(4-hydroxy-2-methoxyphenyl)prop-2-enoic_acid + flavin + H2O
|
1.14.14.91
trans-cinnamate 4-monooxygenase
|
–
|
|
|
BRENDA:
BS386809
|
|
|
|
(2E)-3-(2-ethoxyphenyl)prop-2-enoic_acid + reduced_flavodoxin + O2 <=> (2E)-3-(2-ethoxy-4-hydroxyphenyl)prop-2-enoic_acid + flavin + H2O
|
1.14.14.91
trans-cinnamate 4-monooxygenase
|
–
|
|
|
BRENDA:
BS386806
|
|
|
|
arachidonic_acid + reduced_flavodoxin + O2 <=> 20-hydroxyeicosatetraenoic_acid + 19-hydroxyeicosatetraenoic_acid + flavin + H2O
|
1.14.14.1
unspecific monooxygenase
|
–
|
|
|
BRENDA:
BS414291
|
|
|
|
avermectin + reduced_flavodoxin + O2 <=> 4''''-oxo-avermectin + flavin + H2O
|
1.14.14.1
unspecific monooxygenase
|
–
|
|
|
BRENDA:
BS386377
|
|
|
|
cholesterol + reduced_flavodoxin + O2 <=> 12-hydroxycholesterol + flavin + H2O
|
1.14.14.139
5beta-cholestane-3alpha,7alpha-diol 12alpha-hydroxylase
|
–
|
|
|
BRENDA:
BS386395
|
|
|
|
dihydroquercetin + reduced_flavodoxin + O2 <=> 5''-hydroxydihydroquercetin + flavin + H2O
|
1.14.14.81
flavanoid 3',5'-hydroxylase
|
–
|
|
|
BRENDA:
BS373100
|
|
|
|
dihydrokaempferol + 2 reduced_flavodoxin + 2 O2 <=> 3'',5''-dihydroxy-dihydrokaempferol + 2 flavin + 2 H2O
|
1.14.14.81
flavanoid 3',5'-hydroxylase
|
–
|
|
|
BRENDA:
BS386444
|
|
|
|
elymoclavine + reduced_flavodoxin + O2 <=> paspalic_acid + flavin + H2O
|
1.14.14.1
unspecific monooxygenase
|
–
|
|
|
BRENDA:
BS386460
|
|
|
|
1-chloro-4-(methylsulfanyl)benzene + reduced_flavodoxin + O2 <=> 4-chlorophenyl_methyl_sulfoxide + flavin + H2O
|
1.14.14.1
unspecific monooxygenase
|
–
|
|
|
BRENDA:
BS414099
|
|
|
|
gibberellin_A12 + reduced_flavodoxin + O2 <=> 16alpha,17-epoxy_GA12 + flavin + H2O
|
1.14.14.1
unspecific monooxygenase
|
–
|
|
|
BRENDA:
BS388785
|
|
|
|
gibberellin_a4 + reduced_flavodoxin + O2 <=> 16alpha,17-epoxy_GA4 + flavin + H2O
|
1.14.14.1
unspecific monooxygenase
|
–
|
|
|
BRENDA:
BS386479
|
|
|
|
giberellic_acid_GA9 + reduced_flavodoxin + O2 <=> 16alpha,17-epoxy_GA9 + flavin + H2O
|
1.14.14.1
unspecific monooxygenase
|
–
|
|
|
BRENDA:
BS388787
|
|
|
|
Indene + reduced_flavodoxin + O2 <=> indenol + flavin + H2O
|
1.14.14.1
unspecific monooxygenase
|
–
|
|
|
BRENDA:
BS388923
|
|
|
|
oleandomycin + reduced_flavodoxin + O2 <=> 4-hydroxy-oleandomycin + flavin + H2O
|
1.14.14.1
unspecific monooxygenase
|
–
|
|
|
BRENDA:
BS389442
|
|
|
|
taxadien-5alpha-yl_acetate + reduced_flavodoxin + O2 <=> taxa-4(20),11-dien-5alpha-yl-acetyl-13alpha-ol + flavin + H2O
|
1.14.14.106
taxane 13alpha-hydroxylase
|
–
|
|
|
BRENDA:
BS389850
|
|
|
|
progesterone + reduced_flavodoxin + O2 <=> 17alpha-hydroxyprogesterone + 16alpha-hydroxyprogesterone + flavin + H2O
|
1.14.14.19
steroid 17alpha-monooxygenase
|
–
|
|
|
BRENDA:
BS427512
|
|
|
|
Cinnamic_acid + reduced_flavodoxin + O2 <=> p-coumaric_acid + flavin + H2O
|
1.14.14.92
benzoate 4-monooxygenase
|
–
|
|
|
BRENDA:
BS289256
|
|
|
|
cholesterol_3-sulfate + reduced_flavodoxin + H+ + O2 <=> (24S)-24-hydroxycholesterol_3-sulfate + flavin + H2O
|
1.14.14.25
cholesterol 24-hydroxylase
|
–
|
|
|
BRENDA:
BS396697
|
|
|
|
6-deoxocathasterone + reduced_flavodoxin + O2 <=> 6-deoxoteasterone + flavin + H2O
|
1.14.14.147
3-epi-6-deoxocathasterone 23-monooxygenase
|
–
|
|
|
BRENDA:
BS399752
|
|
|
|
myristic_acid + reduced_flavodoxin + O2 <=> omega-hydroxy-myristic_acid + flavin + H2O
|
1.14.14.1
unspecific monooxygenase
1.14.14.80
long-chain fatty acid omega-monooxygenase
|
–
–
|
|
|
BRENDA:
BS377187
|
|
|
|
taxa-4,11-diene + reduced_flavodoxin + O2 <=> 5(12)-oxa-3(11)-cyclotaxane + flavin + H2O
|
1.14.14.176
taxadiene 5alpha-hydroxylase
|
–
|
|
|
BRENDA:
BS399033
|
|
|
|
(-)-alpha-pinene + reduced_flavodoxin + O2 <=> verbenol + flavin + H2O
|
1.14.14.1
unspecific monooxygenase
|
–
|
|
|
BRENDA:
BS399123
|
|
|
|
(-)-beta-pinene + reduced_flavodoxin + O2 <=> myrtanal + flavin + H2O
|
1.14.14.1
unspecific monooxygenase
|
–
|
|
|
BRENDA:
BS399124
|
|
|
|
(-)-beta-pinene + reduced_flavodoxin + O2 <=> pino-carveol + flavin + H2O
|
1.14.14.1
unspecific monooxygenase
|
–
|
|
|
BRENDA:
BS399125
|
|
|
|
levopimaradienol + reduced_flavodoxin + O2 <=> levopimaradienal + flavin + H2O
|
1.14.14.145
abieta-7,13-dien-18-ol hydroxylase
|
–
|
|
|
BRENDA:
BS389086
|
|
|
|
N,N-dimethylglycine + flavin + H2O <=> sarcosine + formaldehyde + reduced_flavodoxin
|
1.5.8.4
dimethylglycine dehydrogenase
|
–
|
|
|
BRENDA:
BS440333
|
|
|
|
(R)-norreticuline + reduced_flavodoxin + O2 <=> norsalutaridine + flavin + H2O
|
1.14.19.67
salutaridine synthase
|
–
|
|
|
BRENDA:
BS403110
|
|
|
|
syn-[3''D]columbianetin + reduced_flavodoxin + O2 <=> syn-[3''D](anti-3''-hydroxy)-columbianetin + flavin + H2O
|
1.14.14.148
angelicin synthase
|
–
|
|
|
BRENDA:
BS406724
|
|
|
|
3,7-dimethyl-1-octanol + reduced_flavodoxin + O2 <=> 6-hydroxy-3,7-dimethyl-1-octanol + flavin + H2O
|
1.14.14.1
unspecific monooxygenase
|
–
|
|
|
BRENDA:
BS407967
|
|
|
|
(rac)_fenthion_sulfoxide + reduced_flavodoxin + O2 <=> fenthion-sulfone + flavin + H2O
|
1.14.14.1
unspecific monooxygenase
|
–
|
|
|
BRENDA:
BS409404
|
|
|
|
palmitoleoyl-CoA + flavin <=> (2E,9Z)-2,9-hexadecadienoyl-CoA + reduced_flavodoxin
|
1.3.8.8
long-chain acyl-CoA dehydrogenase
|
–
|
|
|
BRENDA:
BS398058
|
|
|
|
(6E)-8-hydroxylinalool + reduced_flavodoxin + O2 <=> (6E)-8-oxolinalool + oxidized_NADPH-hemoprotein_reductase] + H2O
|
1.14.14.84
linalool 8-monooxygenase
|
–
|
|
|
BRENDA:
BS418167
|
|
|
|
N,N-dimethylglycine + flavin + H2O <=> sarcosine + formaldehyde + reduced_flavodoxin + H2O2
|
1.5.8.4
dimethylglycine dehydrogenase
|
–
|
|
|
BRENDA:
BS440334
|
|
|
|
reduced_flavodoxin + menadione <=> flavin + menadiol
|
1.5.5.1
electron-transferring-flavoprotein dehydrogenase
|
–
|
|
|
BRENDA:
BS374550
|
|
|
|
heme + reduced_flavodoxin + O2 <=> biliverdin_IXbeta + biliverdin_IXdelta + Fe2+ + CO + flavin + H2O
|
1.14.14.18
heme oxygenase (biliverdin-producing)
|
–
|
|
|
BRENDA:
BS443867
|
|
|
|
nitrate + reduced_flavodoxin <=> nitrite + flavin + H2O
|
1.7.7.2
ferredoxin---nitrate reductase
|
–
|
|
|
BRENDA:
BS370283
|
|
|
|
Cu+ + flavin + hv <=> Cu2+ + reduced_flavodoxin
|
1.97.1.12
photosystem I
|
–
|
|
|
BRENDA:
BS442538
|
|
|
|
acryloyl-CoA + reduced_flavodoxin <=> propionyl-CoA + electron_transfer_protein
|
1.3.8.1
short-chain acyl-CoA dehydrogenase
|
–
|
|
|
BRENDA:
BS370161
|
|
|
|
trans-2-hexenoyl-CoA + reduced_flavodoxin <=> hexanoyl-CoA + electron_transfer_protein
|
1.3.8.1
short-chain acyl-CoA dehydrogenase
|
–
|
|
|
BRENDA:
BS370164
|
|
|
|
crotonyl-CoA + reduced_flavodoxin <=> butyryl-CoA + electron_transfer_protein
|
1.3.8.1
short-chain acyl-CoA dehydrogenase
|
–
|
B
|
|
BRENDA:
BS370162
|
|
|
|
reduced_flavodoxin + ubiquinone <=> flavin + 6-bis(isoprenyl)ubiquinol
|
1.5.5.1
electron-transferring-flavoprotein dehydrogenase
|
–
|
|
|
BRENDA:
BS374544
|
|
|
|
Fe-heme + reduced_flavodoxin + O2 <=> Biliverdin + Fe2+ + CO + NAD+ + H2O
|
1.14.14.18
heme oxygenase (biliverdin-producing)
|
–
|
|
|
BRENDA:
BS451308
|
|
|
|
5alpha-pregnan-17alpha-ol-3,20-dione + reduced_flavodoxin + O2 <=> 5alpha-androstane-3,17-dione + acetate + flavin + H2O
|
1.14.14.32
17alpha-hydroxyprogesterone deacetylase
|
–
|
|
|
BRENDA:
BS432573
|
|
|
|
17alpha-hydroxypregnenolone + reduced_flavodoxin + O2 <=> dehydroepiandrosterone + acetate + flavin + H2
|
1.14.14.32
17alpha-hydroxyprogesterone deacetylase
|
–
|
|
|
BRENDA:
BS436714
|
|
|
|
7alpha-hydroxypregnenolone + reduced_flavodoxin + O2 <=> dehydroepiandrosterone + acetate + flavin + H2O
|
1.14.14.32
17alpha-hydroxyprogesterone deacetylase
|
–
|
|
|
BRENDA:
BS398630
|
|
|
|
pregnenolone + reduced_flavodoxin + O2 <=> dehydroepiandrosterone + acetate + flavin + H2O
|
1.14.14.32
17alpha-hydroxyprogesterone deacetylase
|
–
|
|
|
BRENDA:
BS443860
|
|
|
|
allopregnanolone + reduced_flavodoxin + O2 <=> 4-androstene-3,17-dione + acetate + flavin + H2O
|
1.14.14.32
17alpha-hydroxyprogesterone deacetylase
|
–
|
|
|
BRENDA:
BS437006
|
|
|
|
ent-kaur-16-ene + 3 NADPH + reduced_flavodoxin + O2 <=> ent-kaur-16-en-19-oate + flavin + H2O
|
1.14.14.86
ent-kaurene monooxygenase
|
–
|
|
|
BRENDA:
BS442395
|
|
|
|
reduced_flavodoxin + 2 [corrinoid_adenosyltransferase]-cob(II)alamin <=> flavin + 2 [corrinoid_adenosyltransferase]-cob(I)alamin
|
2.5.1.17
corrinoid adenosyltransferase
|
–
|
|
|
BRENDA:
BR52457
|
|
|
|
reduced_flavodoxin + 2 [corrinoid_adenosyltransferase]-cob(II)yrinic_acid_a,c-diamide <=> flavin + 2 [corrinoid_adenosyltransferase]-cob(I)yrinic_acid_a,c-diamide
|
2.5.1.17
corrinoid adenosyltransferase
|
–
|
|
|
BRENDA:
BR52460
|
|
|
|
trimethylamine + H2O + semiquinone_electron-transferring_flavoprotein <=> Dimethylamine + formaldehyde + reduced_flavodoxin
|
1.5.8.2
trimethylamine dehydrogenase
|
–
|
|
|
BRENDA:
BS374768
|
|
|
|
reduced_flavodoxin + NADP+ <=> oxidized_flavodoxin_I + NADPH + H+
|
1.18.1.2
ferredoxin---NADP+ reductase
|
–
|
|
|
BRENDA:
BS453861
|
|
|
|
8-O-methylsterigmatocystin + reduced_flavodoxin + O2 <=> aflatoxin_B1 + 2 NADP+ + methanol + flavin + H2O + CO2
|
1.14.14.117
aflatoxin B synthase
|
–
|
|
|
BRENDA:
BS421828
|
|
|
|
oxytetracycline + reduced_flavodoxin + NADPH + O2 <=> 11a-hydroxy-oxytetracycline + flavin + H2O + NADP+
|
1.14.13.231
tetracycline 11a-monooxygenase
|
–
|
|
|
BRENDA:
BS377438
|
|
|
|
7-ethoxyresorufin + reduced_flavodoxin + O2 <=> resorufin + ethanol + flavin + H2O
|
1.14.14.1
unspecific monooxygenase
|
–
|
|
|
BRENDA:
BS414180
|
|
|
|
reduced_flavodoxin + decylubiquinone <=> flavin + decylubiquinol
|
1.5.5.1
electron-transferring-flavoprotein dehydrogenase
|
–
|
|
|
BRENDA:
BS259378
|
|
|
|
6 reduced_flavodoxin + N2 + 6 H2O + 6 ATP <=> 6 flavin + 2 NH3 + 6 H+ + 6 ADP + 6 phosphate
|
1.18.6.1
nitrogenase
1.19.6.1
nitrogenase (flavodoxin)
|
–
–
|
|
|
BRENDA:
BS289220
|
|
|
|
reduced_flavodoxin + H+ + Acetylene + ATP <=> flavin + ethylene + ADP + phosphate
|
1.19.6.1
nitrogenase (flavodoxin)
|
–
|
|
|
BRENDA:
BS406562
|
|
|
|
2 ATP + reduced_flavodoxin + inactive_2-hydroxyglutaryl-CoA_dehydratase + 2 H2O <=> 2 ADP + 2 phosphate + reduced_flavodoxin + active_2-hydroxyglutaryl-CoA_dehydratase
|
5.6.1.9
(R)-2-hydroxyacyl-CoA dehydratase activating ATPase
|
–
|
|
|
BRENDA:
BS448370
|
|
|
|
2 ATP + reduced_flavodoxin + inactive_2-hydroxyisocaproyl-CoA_dehydratase + 2 H2O <=> 2 ADP + 2 phosphate + reduced_flavodoxin + active_2-hydroxyisocaproyl-CoA_dehydratase
|
5.6.1.9
(R)-2-hydroxyacyl-CoA dehydratase activating ATPase
|
–
|
|
|
BRENDA:
BS449171
|
|
|
|
2 ATP + reduced_flavodoxin + inactive_phenyllactate_dehydratase + 2 H2O <=> 2 ADP + 2 phosphate + reduced_flavodoxin + active_phenyllactate_dehydratase
|
5.6.1.9
(R)-2-hydroxyacyl-CoA dehydratase activating ATPase
|
–
|
|
|
BRENDA:
BS449172
|
|
|
|
2-pentenoyl-CoA + oxidized_electron_transfer_flavoprotein <=> pentanoyl-CoA + reduced_flavodoxin
|
1.3.8.1
short-chain acyl-CoA dehydrogenase
|
–
|
|
|
BRENDA:
BS389527
|
|
|
|
S-adenosyl-L-methionine + reduced_flavodoxin + formate_acetyltransferase-glycine <=> 5''-deoxyadenosine + L-methionine + reduced_flavodoxin + formate_acetyltransferase-glycine + H+
|
1.97.1.4
[formate-C-acetyltransferase]-activating enzyme
|
–
|
|
|
BRENDA:
BR1412
|
|
|
|
S-adenosyl-L-methionine + reduced_flavodoxin + formate_acetyltransferase-glycine <=> 5''-deoxyadenosine + L-methionine + flavodoxin + formate_acetyltransferase-glycine-2-yl-radical
|
1.97.1.4
[formate-C-acetyltransferase]-activating enzyme
|
–
|
|
|
BRENDA:
BS6766
|
|
|
|
S-adenosyl-L-methionine + reduced_flavodoxin + [pyruvate_formate-lyase]-glycine <=> L-methionine + 5''-deoxyadenosine + [pyruvate_formate-lyase]-glycine_radical + flavodoxin
|
1.97.1.4
[formate-C-acetyltransferase]-activating enzyme
|
–
|
|
|
BRENDA:
BS451802
|
|
|
|
reduced_flavodoxin + duroquinone <=> flavin + duroquinol
|
1.5.5.1
electron-transferring-flavoprotein dehydrogenase
|
–
|
|
|
BRENDA:
BS374547
|
|